175,390 research outputs found
Protocol for live imaging of axonal transport in iPSC-derived iNeurons
No full textSummary: Studies of human induced pluripotent stem cell (iPSC)-derived neurons promise important insights into neurodegenerative diseases. Here, we present a protocol for live imaging of axonal transport in glutamatergic iPSC-derived neurons (iNeurons). We describe steps for the differentiation of iPSCs into iNeurons via PiggyBac-mediated neurogenin 2 (NGN2) delivery, iNeuron culture and transfection, and the acquisition and analysis of time-lapse images. Our protocol is optimized for the widely available catalog of KOLF2.1J iPSCs with mutations relevant to neurodegenerative diseases but is also applicable to other iPSC lines.For complete details on the use and execution of this protocol, please refer to Dou et al.1,2 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics
F. C. Ostrander,Li Romans dou Lis, 1915
No full textLångfors Arthur. F. C. Ostrander,Li Romans dou Lis, 1915. In: Romania, tome 45 n°177, 1918. pp. 137-139
A Note on the Quantificational Expression Dou in Mandarin Chinese
No full text1. はじめに 2. 説明対象となる現象 3. 分析 4. Cheng(1995) 5. 今後の課題According to the literature, dou in Chinese is an element which quantifies the NP preceding it. In this paper, I argue that dou also affects the interpretation of the Event appearing after it. I propose syntactic functions of dou, summarized as follows:i. Dou is located in the Spec position of the Event and is the head of the predicate taking α (an NP which c-commands dou) and the Event as arguments.ii. Dou divides α into n pieces.iii. Dou divides the Event into m pieces.iv. The operations (ii) and (iii) must universally apply to α and to the Event
Topic-Focus Structure and Quantification of Dou 'all'
No full textThis paper examines a type of dou quantification found in wh-questions such as ta dou mai le shenme? ‘What are all the things that he bought?’ This type is different from the well-known dou quantification in that the leftness condition cannot be applied to the former. I propose that the former type of quantification is subject to the topic-focus structure rather than to the syntactic structure, which means that the domain of the quantification is determined in relation to 'old' and 'new' information of a sentence. Sentences including dou can be divided into topic and focus, and each part is mapped onto the restrictor and the nuclear scope in a tripartite structure of dou quantification. This analysis accounts for the reason why a list answer is appropriate to questions with dou, why wh-words in the questions cannot be quantity expressions, and why wh-words should either have a plural interpretation or take the plural form. This analysis also explains the distribution of dou, i.e., dou should c-command a focused phrase. Finally, I point out that the analysis can extend to declaratives which are rare but still observable, and that the two types of dou quantification can arise simultaneously
hier by gevoeght het Tractat van de Landt-maten door J. P. Dou, ende C. Eversdijck, ende andere, &c
No full textDoor Mattheus van Nispe
中国語のdou量化の認可条件
No full textHsu (2010) proposes the following syntactic licensing condition with respect to the dou-quantification in Mandarin Chinese: dou-quantification is possible iff a chain is formed, in which α_i c-commands dou and dou c-commands e_i, which is an empty category coindexed with α_i and contained in the vP internal position. This paper argues against Hsu (2010) by showing that some of the observations put forth in Hsu (2010) are inadequate: (ⅰ) dou-quantification over the subject DP is sometimes possible in spite of the fact that dou does not c-command the trace position of the subject DP; (ⅱ) dou-quantification over a topicalized DP becomes impossible when the topicalized DP does not have a θ-position in vP; (ⅲ) dou-quantification over a topicalized DP is sometimes impossible in spite of the fact that it has a coindexed empty category within vP.1.はじめに 2.Hsu(2010)の観察 3.Hsuの分析 4.Hsu(2010)の分析の問題点 5.まと
Hunting equipment from Dengwe and Dou Pos.
No full text<p>A. Detail of Dengwe quiver with arrows. Note the <i>Sansevieria</i> leaf above the quiver; B. Dengwe hunting bag with bow and quiver (made from blue plastic pipe); C. Black <i>Ozoroa schinzii</i> adhesive and yellow <i>Terminalia sericea</i> gum on <i>Grewia flava</i> stick that is both an applicator and storage device (from Dou Pos).</p
The limitations of electric cargo bikes – a systematic literature review
No full textPurpose - The aim of this paper is to discern the knowledge from the literature by conducting a literature review to provide ECB users with insight into the limitation of ECBs that affect their penetration and the relationships among these limitations themselves and the advantages of ECCs; and secondly, to outline directions for further research.
Design/methodology/approach - During the systematic review process, a search protocol was developed after the initial snowball sampling process. Then keywords regarding cargo bikes are used to find the potential papers on Scopus. Afterwards, 42 scientific journals papers and 29 conference proceeding papers published in English were selected. Finally, 17 papers are excluded according to specific criteria by reviewing the contents of the selected papers.
Findings –Seven limitations of ECCs regarding payload capacity, battery range, riding speed, charging time, terrain adaptability, the possibility of defect/malfunction, and service monotony were identified from the literature. The interacting relationships among these limitations showed that the deterioration of one limitation can have negative impact on other limitations. More importantly, the improvement of one limitation may have negative impact on other limitation. In addition, the changes in both directions (improve/deteriorate) of the limitations can also overshadow some of the advantages of ECCs. Finally, research gaps and relevant further research directions were identified.
Originality/Value - The results of this paper provide insights with academic and practitioners. To our best knowledge, this study is the first paper to investigate the interacting mechanism among the limitation of ECBs themselves and the advantages of ECCs, which enriches the knowledge of ECCs in the existing relevant literature. From the practical perspective, the review paper provides stakeholders with a theoretical support for the understanding and decision-making on the adoption of ECCs, potentially reducing the concerns and reservations against the adoption of ECCs.
Practical implications - When deciding to introduce ECBs, logistics service providers (LSPs) are suggested to focus on the ECB's cargo capacity and battery mileage according to the specific service market. The above two parameters will not only affect the initial investment, and mid-term operation economy but also affect the later maintenance cost. At the same time, the LSP should adjust the above two parameters according to the terrain of the operating environment. In addition, optimising space-saving loading and packing operations are even more important than conventional transportation modes in urban logistics because the low use of vehicle capacity will reduce the effectiveness of last-mile logistics. It is also important to note that not all limitations of ECCs hold equal significance for ECC users. Hence, users must learn to differentiate which limitations to ignore and which limitations to address based on their specific circumstances
中国語の量化表現dou(都)に関する一考察
No full textAccording to the literature, dou in Chinese is an element which quantifies the NP preceding it. In this paper, I argue that dou also affects the interpretation of the Event appearing after it. I propose syntactic functions of dou, summarized as follows:i. Dou is located in the Spec position of the Event and is the head of the predicate taking α (an NP which c-commands dou) and the Event as arguments.ii. Dou divides α into n pieces.iii. Dou divides the Event into m pieces.iv. The operations (ii) and (iii) must universally apply to α and to the Event.1. はじめに 2. 説明対象となる現象 3. 分析 4. Cheng(1995) 5. 今後の課
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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