363 research outputs found
The North is another country. by Nicolas Rothwell
No full texttag=1 data=The North is another country. by Nicolas Rothwell
tag=2 data=Rothwell, Nicolas
tag=3 data=Australian Magazine,
tag=6 data=16/17 November 1996
tag=7 data=20-33.
tag=8 data=NT%TOURISM
tag=10 data=Worse, better, stranger, wilder, but above all different from the rest of the country. Continuing his journey of discovery across Australia's Top half the author stops over in Darwin to hear all the truths and whispers about the North.
tag=11 data=1996/2/8
tag=12 data=96/0316
tag=13 data=CABWorse, better, stranger, wilder, but above all different from the rest of the country. Continuing his journey of discovery across Australia's Top half the author stops over in Darwin to hear all the truths and whispers about the North
Supplemental material for Age and sex-specific associations of carotid pulsatility with small vessel disease burden in transient ischemic attack and ischemic stroke
No full textSupplemental material for Age and sex-specific associations of carotid pulsatility with small vessel disease burden in transient ischemic attack and ischemic stroke by Kui Kai Lau, Petra Pego, Sara Mazzucco, Linxin Li, Dominic PJ Howard, Wilhelm Küker and Peter M Rothwell in International Journal of Stroke</p
Organization Development Experiences . A Case for Enriching HRD through OD
No full textThis article reviews a few definitions of OD and identifies eight characters that are necessary to call an activity or experience as an OD activity or experience. The article then goes on to examine ten case studies (of research, consulting and OD) of what appears like an OD activity in which the author was involved as one of the facilitators for whole system or subsystem and examines each on of them for their appropriateness to be called as OD interventions. The author then goes on to derive some lessons from these experiences. The article outlines also some advantages of using traditional OD approach in various HRD interventions and offers some suggestions for making specific HRD interventions like competency mapping, 360Degree Feedback based leadership Development and Assessment and Development Centers as OD activities. The paper concludes that using an OD approach enriches HRD and yields a good ROI on HRD interventions.
Age and sex-specific associations of carotid pulsatility with small vessel disease burden in transient ischemic attack and ischemic stroke
No full textBackground Although large artery stiffness has been implicated in the pathogenesis of cerebral small vessel disease, whether carotid pulsatility, a convenient surrogate marker of arterial stiffness, is similarly associated with global burden of small vessel disease is unknown.Aims To determine the age and sex-specific associations of carotid pulsatility with global burden of small vessel disease.Methods We studied consecutive patients with transient ischemic attack or non-disabling ischemic stroke from the Oxford Vascular Study who had a brain MRI and carotid duplex ultrasound during 2002-2014. We determined clinical correlates of common carotid artery (CCA) and internal carotid artery (ICA) pulsatility index (PI) and their associations with the total small vessel disease score on MRI, stratified by age (median=72).Results In 587 patients, correlates of CCA and ICA-PI were both independently associated with age, diabetes, and premorbid mean pulse pressure after adjustment for age, sex, and cardiovascular risk factors (all p0.05). No associations between CCA-PI with small vessel disease score were noted at any age. In 94 consecutive patients who also received transcranial Doppler ultrasound, strong associations between middle cerebral artery (MCA)-PI and an increasing small vessel disease score were noted (unadjusted OR-MCA: 4.26, 1.45-12.55, p=0.009; ICA: 2.37, 0.81-6.87, p=0.11; CCA: 1.33, 0.45-3.96, p=0.61).Conclusions ICA and MCA-PI are associated with global small vessel disease burden, especially in individuals aged<70 and may be causally related
Dispersion measurements across broad wavelength ranges by low-coherence interferometry
No full textJ. H. Rothwell, D. F. Murphy, M. AlHourani and D. A. Flavi
Regaining Motor Control in Musician's Dystonia by Restoring Sensorimotor Organization
No full textProfessional musicians are an excellent human model of long term effects of skilled motor training on the structure and function of the motor system. However, such effects are accompanied by an increased risk of developing motor abnormalities, in particular musician's dystonia. Previously we found that there was an expanded spatial integration of proprioceptive input into the hand area of motor cortex (sensorimotor organisation, SMO) in healthy musicians as tested with a transcranial magnetic stimulation (TMS) paradigm. In musician's dystonia, this expansion was even larger, resulting in a complete lack of somatotopic organisation. We hypothesised that the disordered motor control in musician's dystonia is a consequence of the disordered SMO.
In the present paper we test this idea by giving pianists with musician's dystonia 15 min experience of a modified proprioceptive training task. This restored SMO towards that seen in healthy pianists. Crucially, motor control of the affected task improved significantly and objectively as measured with a MIDI piano, and the amount of behavioural improvement was significantly correlated to the degree of sensorimotor re-organisation. In healthy pianists and non-musicians, the SMO and motor performance remained essentially unchanged. These findings suggest a link between the differentiation of SMO in the hand motor cortex and the degree of motor control of intensively practiced tasks in highly skilled individuals
Piloting a novel multidisciplinary telepharmacy medication review service in a rural community
No full textIn Australia, the percentages of hospital admissions due to adverse drug events range from 5.6% in the general population and 30.4% in the elderly population.1 It has been established that inappropriate medication management and medication related problems (MRPs) are a leading preventable cause of hospital admissions2,3 and is also the most likely major contributing factor to 30 day post-discharge readmission in high risk patients; research by the author identified that 25–27% of 30-day readmissions in rural and regional hospitals are due to medicatio
Technology, Structural Change and Manufacturing Employment
No full textThis paper presents a revised version of Roy Rothwell's contribution to the IIASA Task Force Meeting on "Innovation and Industrial Strategy" in June 1980. It shows the heavy impact of technical change on employment both from the side of processes and products. Discussing the economic mechanisms of long waves the author mentions "...The fact that Menschs' inventions are rather more spread over time than his bunches of innovations, certainly suggests that other factors play a part in forcing their commercialization." Those factors are the self-reinforcing pressures of capital accumulation, which result in higher capital intensity and lower profitability until capital investment peaks out and begins to decline. Roy Rothwell comes to some conclusions for the policy to be applied. In his opinion governments, via market economies, might help to accelerate the formation of new industries through the process of innovative procurement in the public sector
Cerebellar Theta-Burst Stimulation Impairs Memory Consolidation in Eyeblink Classical Conditioning
No full textAssociative learning of sensorimotor contingences, as it occurs in eyeblink classical conditioning (EBCC), is known to involve the cerebellum, but its mechanism remains controversial. EBCC involves a sequence of learning processes which are thought to occur in the cerebellar cortex and deep cerebellar nuclei. Recently, the extinction phase of EBCC has been shown to be modulated after one week by cerebellar continuous theta-burst stimulation (cTBS). Here, we asked whether cerebellar cTBS could affect retention and reacquisition of conditioned responses (CRs) tested immediately after conditioning. We also investigated a possible lateralized cerebellar control of EBCC by applying cTBS on both the right and left cerebellar hemispheres. Both right and left cerebellar cTBSs induced a statistically significant impairment in retention and new acquisition of conditioned responses (CRs), the disruption effect being marginally more effective when the left cerebellar hemisphere was stimulated. These data support a model in which cTBS impairs retention and reacquisition of CR in the cerebellum, possibly by interfering with the transfer of memory to the deep cerebellar nuclei
Oregon poverty measure project
No full textDavid W. Rothwell, OSU College of Public Health and Human Sciences, Leanne S. Giordono, OSU College of Public Health and Human Sciences, Bruce A. Weber, OSU Department of Applied Economics.Title from PDF cover (viewed on October 23, 2020).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (pages 33-36).This project is made possible with funding from The Ford Family Foundation and the Providence Health Foundation.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
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