185 research outputs found

    First person – Akash Gupta

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    First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Akash Gupta is first author on ‘A novel and cost-effective ex vivo orthotopic model for the study of human breast cancer in mouse mammary gland organ culture’, published in BiO. Akash conducted the research described in this article while a PhD Scholar in Rajendra Mehta's lab at IIT Research Institute, Chicago, USA. He is now an assistant research scientist in the lab of Syreeta L. Tilghman at the University of Arizona, Department of Medicine, Tucson, USA, investigating drug efficacy modeling using human organoids culture for the treatment of cancers

    akashkoppa/global-water-energy-closure: global water and energy balance closure

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    Contains data and scripts for reproducing the results of the research article titled 'Closing the Combined Water and Energy Balance of Global Watersheds from Earth Observations' Authors: Akash Koppa1, Sarfaraz Alam1, Diego G. Miralles2, and Mekonnen Gebremichael1 1Department of Civil and Environmental Engineering, University of California, Los Angeles, CA, USA 2Hydro-Climate Extremes Lab (H-CEL), Ghent University, Coupure Links 653, 9000 Ghent, Belgium Corresponding author: Akash Koppa ([email protected]

    Multi-radio interference diagnosis in unlicensed bands using passive monitoring

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    The increasing density and data rate of unlicensed band wireless devices has led to significant inter- and intra-radio interference problems. Multiple competing standards such as the IEEE 802.11b/g, Bluetooth and ZigBee, all of which operate in the 2.4 GHz ISM band, can interfere with each other when used in typical indoor environments, potentially causing significant performance degradation. This thesis aims to characterize different types of heterogeneous interference in the 2.4 GHz unlicensed band and develop techniques to diagnose interference related problems using passive monitoring. The first part of the thesis presents detailed experimental results (using the ORBIT radio grid testbed) to quantify the effects of such interference in representative small office and home (SOHO) environment. In particular, different topologies, traffic loads and number of interfering devices are emulated to show the impact of multi-radio interference and to characterize each kind of interference. The second part of the thesis describes a cross-layer, multi-radio interference diagnosis framework (called “spectrum MRI”) which aims to classify and diagnose multi-radio interference problems using heuristic and model-based methods. Validation experiments show that broad auto-classification of multi-radio interference in terms of congestion, slow links, inter AP interference and Bluetooth interference is possible using heuristic algorithms and passive monitoring.M.S.Includes bibliographical referencesby Akash Bai

    Book review: Comparing devolved governance

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    "Comparing Devolved Governance." Derek Birrell. Palgrave Macmillan. May 2012. --- In Comparing Devolved Governance, Derek Birrell compares the separate governments and legislatures of Scotland, Wales and Northern Ireland. Akash Paun finds that the author comprehensively and successfully describes and compares the three political systems that are too often discussed separately. However, the book does not quite amount to more than the sum of its (many and good) parts, and was frustrating for what it did not do, such as make the case for why the question of asymmetry is so important. This is nonetheless a useful and thorough reference work for students and researchers of devolution

    akym/SX3-Calibration: Teensy program for SX3 calibration control box - Alpha

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    SX3-Calibration <p>SX3 Thrust Calibration and measurement Program for Teensy 3.6</p> Usage Instruction <p>Download this file and compile 'sx3_cal.ino' using Arduino IDE and upload to Teensy via Teensy loader. Make sure you have the support libraries from <a href="https://zenodo.org/badge/latestdoi/133398390"></a>.</p> Current Function Mapping Switch Function F1 Lock thrust balance F2 Decouple thrust balance F3 Calibrate F4 Preload Force Sensor F5 Deload Force Sensor F6 Stop Preload/Deload Author <p>Akash Mankar</p&gt

    Surface assembly of nano-metalorganic framework on amine functionalized indium tin oxide substrate for impedimetric sensing of parathion

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    The present paper reports the assembly and pesticide sensing application of a nanometal organic framework [Cd(atc)(H2O)2]n (‘atc’=2-aminoterephthalic acid). The assembly of the NMOF film has been achieved by sequential dipping of a 2-aminobenzylamine (2-ABA) modified indium tin oxide (ITO) slide in organic linker ‘atc’ and metal ion ‘Cd2+’ solutions. The different structural and morphological characteristics of the NMOF thin film have been characterized. The availability of pendent –COOH functional groups on the assembled NMOF film is exploited to synthesize a pesticide immunosensor by conjugating the NMOF film with anti-parathion antibody. This immunosensor has been explored for the electrochemical impedance spectroscopy (EIS) based analysis of parathion in the concentration range of 0.1–20 ng/mL. The proposed detection is specific with respect to other organophosphate compounds, e.g. malathion, paraoxon, fenitrothion, monochrotophos and dichlorovos. The proposed sensor shows the detection limit of 0.1 ng/mL and it is applicable for analysis of parathion in a rice sample. The sensor's performance is validated by comparting the obtained results with gas chromatographic data.Authors gratefully acknowledge the financial grant from CSIR India through project OMEGA/PSC0202/2.2.5. We are thankful to the Director, CSIR-CSIO, Chandigarh, India. The fourth author acknowledges partial financial support from the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (MEST) (No. 2009-0093848)

    LAB: Large-Scale Alignment for ChatBots

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    This work introduces LAB (Large-scale Alignment for chatBots), a novel methodology designed to overcome the scalability challenges in the instruction-tuning phase of large language model (LLM) training. Leveraging a taxonomy-guided synthetic data generation process and a multi-phase tuning framework, LAB significantly reduces reliance on expensive human annotations and proprietary models like GPT-4. We demonstrate that LAB-trained models can achieve competitive performance across several benchmarks compared to models trained with traditional human-annotated or GPT-4 generated synthetic data. Thus offering a scalable, cost-effective solution for enhancing LLM capabilities and instruction-following behaviors without the drawbacks of catastrophic forgetting, marking a step forward in the efficient training of LLMs for a wide range of applications.Comment: Corresponding Author: Akash Srivastava. Equal Contribution: Shivchander Sudalairaj, Abhishek Bhandwaldar, Aldo Pareja, Akash Srivastava, Code: https://github.com/instructla

    Polycyclic aromatic hydrocarbons and volatile organic compounds in biochar and biochar-amended soil:a review

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    Residual pollutants including polycyclic aromatic hydrocarbons (PAHs), volatile organic compounds (VOCs), and carbon (aceous) nanoparticles are inevitably generated during the pyrolysis of waste biomass and remain on the solid coproduct called biochar. Such pollutants could have adverse effects on the plant growth as well as microbial community in soil. Although biochar has been proposed as a ‘carbon negative strategy’ to mitigate the greenhouse gas emissions, the impacts of its application with respect to long-term persistence and bioavailability of hazardous components are not clear. Moreover, the co-occurrence of low molecular weight VOCs with PAHs in biochar may exert further phytotoxic effects. This review describes the basic need to unravel key mechanisms driving the storage vs. emission of these organics and the dynamics between the sorbent (biochar) and soil microbes. Moreover, there is an urgent need for standardized methods for quantitative analysis of PAHs and VOCs in biochar under environmentally relevant conditions. This review is also extended to cover current research gaps including the influence of biochar application on the short- and long-term fate of PAHs and VOCs and the proper control tactics for biochar quality and associated risk.This study was supported by a grant from the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (MEST) (No. 2009-0093848). This work was also carried out with the support of the 'Cooperative Research Program for Agriculture Science & Technology Development' (Project title: Study on model development to control odor from hogpens, Project No. PJ01052101) Rural Development Administration, Republic of Korea. The second author also acknowledges the support made by a National Research Foundation of Korea (NRF) Grant funded by the Korean Government (MSIP) (No. 2014RA1A004893)

    Modulation of African lightning and rainfall by the global five day wave

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    Thesis (S.M. and S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2001.Includes bibliographical references (leaves 169-176).This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Using a field station in Rhode Island, we record electromagnetic transients caused by global mesoscale lightning activity in the Schumann resonance band (3Hz-50Hz). For this thesis, mesoscale lightning flashes originating in Africa were analyzed and compared to the phase and amplitude of a five day global pressure wave and African easterly waves. Evidence was also presented for the mesoscale lightning to be correlated with African rainfall and kinetic energy. The five day global pressure wave was located in terms of phase and amplitude for every day of the years 1989, 1996, and 1998. This global pressure wave seems to have a certain phase relationship with African convection and could possibly be modulating rainfall and lightning by a factor of two. Evidence is also presented for the possible modulation of African easterly waves by the five day wave.by Akash C. Patel.S.M.and S.B

    Structural Health Monitoring Systems and Methods

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