1,964,278 research outputs found
Jessy-Ding/Transcriptomic_oSPARC: v1.0.0
No full textFull Changelog: https://github.com/Jessy-Ding/Transcriptomic_oSPARC/commits/v1.0.
Replication Data for: Technology and the Rise of Great Powers
No full textThis Dataverse provides the data and code to replicate all analyses in Ding, Jeffrey (forthcoming): Technology and the Rise of Great Powers, published by Princeton University Press
Supplementary materials for ``Bayesian causal inference: a critical review''
No full textSome background materials and R code for the paper: Li, F., Ding, P. and Mealli, F. (2023). Bayesian causal inference: a critical review. Philosophical Transactions of the Royal Society A, 381, 20220153
Clues, flow channels, and cognitive states: an exploratory study of customer experiences with e-brokerage services
No full textPeer reviewe
The relationship of the ADP-ribosylating enzyme from S. solfataricus with DING proteins and its intracellular localization
No full textThe PARPSso thermoprotein from Sulfolobus solfataricus has been identified as a PARP-like enzyme that cleaves -NAD+ to synthesize oligomers of ADP-ribose and cross-reacts with polyclonal anti-PARP-1 catalytic site antibodies. Despite the biochemical properties that allow to correlate it to PARP enzymes, the N-terminal and partial amino acid sequence suggest the sulfolobal enzyme belongs to a different class of enzymes, the DING proteins. Considering the high sequence identity with the human DING protein HPBP and the lack of a nucleotide coding sequence in both human and sulfolobal genomes, we hypothesized that PARPSso might share other features with the human DING. Further analysis of PARPSso amino acid sequence addressed the research towards studying other possible similarities between human and sulfolobal protein and then to explain how PARPSso correlates with canonic PARPs. For the latter question, the peculiar behaviour of the thermozyme, that is biochemically, but not structurally related to the classic PARPs, stimulated to investigate by computational analysis and databank, whether the protein might be phylogenetically related to any already known PARP amino acid sequence.
Moreover, immunochemical and enzymatic crossed analyses were performed to establish whether purified HPBP and PARPSso have common immunoreactive and functional behaviour.
The second part of the research was focused on the localization of PARPSso within the sulfolobal cell. Our interest to this item arose from the property of some DING proteins to be membrane bound, suggested to work as membrane transporters. On the other hand, from previous studies, it is known that PARPSso is only partially solubilized from the starting cell homogenate provided by ICMIB (CNR), and the soluble enzyme is strictly associated with DNA. In this thesis work, whole cells collected by centrifugation from culture medium were subjected to a different extraction procedure. This procedure included also experimental conditions used to differentiate between soluble (i.e. cytoplasmic) and insoluble (i.e. membrane-bound) protein fractions. PARPSso and DNA distributions were determined by enzyme assay, immunoblotting and agarose gel electrophoresis. Reciprocal interactions of thermozyme, nucleic acid and membrane lipids were investigated with different techniques and methodologies (nucleoid preparation, fluorescence binding assays, fluorescence microscopy analysis)
Replication Data for: Model-assisted analyses of cluster-randomized experiments
No full textR code and datasets for
“Model-assisted analyses of cluster-randomized experiments” by Su and Ding, which will appear in the Journal of the Royal Statistical Society, Series B
Resume: DING Yi
No full textThis resume is scripted in both languages of Chinese and English. A business card of DING Yi is attached to this resume (see the attached file to this document entry). (Jerry Wu\u2723).https://digital.kenyon.edu/zhoudocs/1053/thumbnail.jp
Shu: Zhu zi ding ding Cai shi ji zhuan : [6 juan. v.1
No full text朱熹訂定 ; 蔡沈集傳 ; 董鼎輯錄]書名據卷一卷端.Shu ming ju juan yi juan duan.Zhu Xi ding ding ; Cai Shen ji zhuan ; Dong Dong ji lu
A design for Six Sigma case study: creating an IT change management system for a mid-size accounting firm
No full textPeer reviewe
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