102,051 research outputs found

    Development of innovative industrial cluster strategy using compound real options

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    The subject of the study is pilot clusters that are beneficial to a particular region, taking into account the traditions and production areas of the region. The work aims to develop an innovative strategy for state-supported pilot clusters that would allow for flexible management decision making. The proposed method involves the compound real options to be employed in the following order: 1) an option to reduce and abandon the cluster strategy; 2) an option to develop and replicate the experience accumulated in the cluster; 3) an option to switch from and temporarily stop the cluster strategy; and 4) an option to postpone the implementation of the new cluster strategy. As an example of the implementation of the method presented, the authors discuss the strategy for the development of a pilot electric power cluster in the Nizhny Novgorod region presented by the core company TNS energo NN PJSC. The use of the compound real option method enabled the cost increase of the strategy for this cluster – i.e., the effect of its implementation by the core company rose by 89.1%, from 2 710 022 to 5 124 706 thousand Rubles. Thus, using the compound real options precisely in the presented order avoids unreasonable management decisions to exit the current cluster strategy, which would include many tactical opportunities already implemented for cluster development. First, a put option, i.e., an option to reduce and exit the cluster strategy, supplements the evaluation of the current strategy. If the current strategy continues, the other three options are used

    Letter, [Author unclear] to Paulina T. Merritt

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    Handwritten letter to Paulina Merritt from an unknown author, October 1, 1876.

    Handwritten biographical information on Paulina T. McClung Merritt

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    A handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.

    Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.

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    IFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Pelevin’s Trinity in the novel “t”: author – protagonist – reader

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    The article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology

    Measuring industry-science links through inventor-author relations: A profiling method

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    In this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;

    Wave turbulence of a rotating array of quantized vortices in the T → 0 temperature limit

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    The dynamics of quantized vortices in the zero temperature limit T0T \rightarrow 0 is currently of great interest, particularly in the case of the Fermi superfluid 3^3He-B. Here we study wave turbulence, generated by the librating motion of a rotating cylindrical container filled with 3^3He-B, in the limit of vanishing viscous forces at temperatures T0.2TcT \leq 0.2 T_{c}. The polarization of the quantized vortices with respect to the axis of rotation is measured using non-invasive NMR techniques. We observe a decrease of the polarization when the librating motion is started, and a two-stage relaxation process when the modulation of the rotation velocity is stopped. The first relaxation process is associated with the dissipation of large-scale flow stored in inertial waves and the solid body rotation of the vortex array. From the decay of these energy reservoirs we determine the rate of energy dissipation of large-scale flow. The later second process is related to the relaxation of Kelvin waves on individual vortices. This process is monitored by the recovery of the polarization. The existence of a Kelvin wave cascade at the lowest temperatures is currently a central open question. We supply some evidence for the cascade

    Analysis of the magnetotransport channels in tunnel junctions with amorphous

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    This work concerns the temperature and bias dependence of the magnetotransport properties of \chem{Al} oxide-based tunnel junctions with an amorphous \chem{Co_{60}Fe_{20}B_{20}} soft ferromagnetic electrode and \chem{CoFe_{10}}-based polycrystalline hard electrode. The junctions present high tunnel magnetoresistance of 50\sim 50% at room temperature and 71\sim 71% at 5\un{K}. A model that takes magnon-assisted inelastic tunneling into account fits satisfactorily the parallel (P) and antiparallel (AP) conductance as a function of temperature. The extracted fitting parameters are then used to reproduce the low-bias anomaly of the P and AP conductance at low temperature

    Functional diversity changes over 100 yr of primary succession on a volcanic island: insights into assembly processes

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    Changes in species diversity following volcanic eruptions have been studied extensively, but our knowledge on functional diversity and community assembly under such conditions is very limited. Here, we study the processes following the destruction of vegetation after a volcanic eruption. Specifically, we investigate (1) the temporal patterns of taxonomic and functional diversity over time since a previous eruption (alpha diversity) and beta diversity, (2) the temporal patterns of 26 individual traits (vegetative characteristics, plant taxa ecological preferences, and regenerative characteristics) providing more detailed information on species strategies at the initial and later stages of succession, and (3) the processes driving species assembly and whether they changed over time since the eruption an eruption. We analyzed data recorded during five floristic censuses that took place between 1911 and 2011, calculated alpha and beta facets of taxonomic and functional diversity and examined how community structure changed over time, using 26 functional characteristics, based on their ability to discern primary from later colonists, including longevity, growth form, Ellenberg’s indicator values, seed production and weight, flower size and sex, pollination type, and dispersal mode. Null model analysis was used to test whether the observed functional diversity deviates from random expectations. Alpha diversity, both taxonomic and functional, increased over time after an eruption, while beta diversity did not display a clear trend. This finding indicates that mainly abiotic processes determine species assembly over time after an eruption (at least for the time span studied here), contrary to theoretical expectations. It is most interesting that, simultaneously, some aspects of diversity indicated the effect of biotic interactions (facilitation and competition) on the assembly of species a few years after an eruption. This finding implies a legacy effect, since a high percentage of perennial species was noticed in the assemblage right after the eruption, as well as the effect of the harsh environmental conditions on the assembly of the plant communities. In conclusion, our results indicate the role of legacy effects in succession (most probably through the survival of underground plant parts) and underline the importance of disturbance history in providing the context needed for understanding effects of past events on succession
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