45 research outputs found
eSEEd: emotional State Estimation based on Eye-tracking dataset
No full text<p>We present eSEEd- emotional State Estimation based on Eye-tracking database. Eye movements of 48 participants were recorded as they watched 10 emotion evoking videos each of them followed by a neutral video. Participants rated five emotions (tenderness, anger, disgust, sadness, neutral) on a scale from 0 to 10, later translated in terms of emotional arousal and valence levels. Furthermore, each participant filled 3 self-assessment questionnaires. An extensive analysis of the participants' answers to the questionnaires self-assessment scores as well as their ratings during the experiments is presented. Moreover, eye and gaze features were extracted from the low level eye recorded metrics and their correlations with the participants' ratings are investigated. Finally, analysis and results are presented for machine learning approaches, for the classification of various arousal and valence levels based solely on eye and gaze features. The dataset is made publicly available and we encourage other researchers to use it for testing new methods and analytic pipelines for the estimation of an individual's affective state.<br><br>TO USE THIS DATASET PLEASE CITE:<br>Skaramagkas, V.; Ktistakis, E.; Manousos, D.; Kazantzaki, E.; Tachos, N.S.; Tripoliti, E.; Fotiadis, D.I.; Tsiknakis, M. eSEE-d: Emotional State Estimation Based on Eye-Tracking Dataset. <em>Brain Sci.</em> 2023, <em>13</em>, 589. https://doi.org/10.3390/brainsci13040589</p><p>This project has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement No 826429 (Project: SeeFar). This paper reflects only the author's view and the Commission is not responsible for any use that may be made of the information it contains. Please cite: Skaramagkas, V.; Ktistakis, E.; Manousos, D.; Kazantzaki, E.; Tachos, N.S.; Tripoliti, E.; Fotiadis, D.I.; Tsiknakis, M. eSEE-d: Emotional State Estimation Based on Eye-Tracking Dataset. <em>Brain Sci.</em> <strong>2023</strong>, <em>13</em>, 589. https://doi.org/10.3390/brainsci13040589</p>
Treatment of Malignancy Arising in Pilonidal Disease
No full textBackground: Malignant degeneration is a rare complication of pilonidal disease and is associated with a high recurrence rate and poor prognosis compared with regular nonmelanoma skin cancer. Treatment in our departments and in the international literature was evaluated.Methods: We analyzed the data from three patients with malignant degeneration who were treated in our departments and an additional 56 patients who were found after an extensive literature search.Results: A total of 47 males and 12 females, with a mean age of 52 years, were most frequently primarily treated with surgery. After a mean follow-up time of 28 months, 20% of all patients died with evidence of disease and an additional 10% died of unrelated causes. The overall recurrence rate was 39%, with a median time to recurrence of only 9 months. The local recurrence rate was lower when radiotherapy was added to surgical treatment alone (30% vs. 44%). Re-excision of local recurrence resulted in some long-term survivals.Conclusions: Early diagnosis and treatment may lead to improvement of the relative poor prognosis. Surgical treatment should be tailored according to the locoregional extent. The high recurrence rate after surgical treatment can be reduced by the addition of radiotherapy. Although repeat surgery for recurrent disease may involve extensive resection and morbidity, this may result in prolonged survival
Łojasiewicz–Simon gradient inequalities for coupled Yang–Mills energy functions
No full textWe prove Lojasiewicz–Simon gradient inequalities for coupled Yang–Mills energy functions using Sobolev spaces which impose minimal regularity requirements on pairs of connections and sections. The Lojasiewicz–Simon gradient inequalities for coupled Yang–Mills energy functions generalize that of the pure Yang–Mills energy function due to the first author (Feehan, 2014) for base manifolds of arbitrary dimension and due to R˚ade (1992, Proposition 7.2) for dimensions two and three
Economic evaluation of intravenous iron treatments in the management of anemia patients in Greece
No full textVassilis Fragoulakis1, Georgia Kourlaba1, Dimitris Goumenos2, Manousos Konstantoulakis3, Nikolaos Maniadakis11Department of Health Services Management, National School of Public Health, Athens, 2Department of Medicine University Hospital of Patras, Patras, 3Department of Medicine, Athens Medical School, Athens, GreecePurpose: To conduct an economic evaluation comparing Ferinject&reg; (ferric carboxymaltose [FCM]) with Venofer&reg; (iron sucrose [IS]) and CosmoFer&reg; (low-molecular-weight iron dextran [LMWID]) in the management of iron deficiency anemia in Greece.Patients and methods: A cost-minimization analysis was conducted since there are no clear data indicating that one of these regimens is superior to the others in terms of efficacy. Main data inputs were based on bibliography and validated by clinicians. The economic evaluation was conducted for inpatients (ie, surgical patients or patients hospitalized due to a disease related to chronic or acute blood loss) and outpatients (eg, nondialysis chronic kidney disease patients), separately. Analysis was carried out from a National Health Service (NHS) perspective and also from a patient perspective. Total cost treatment reflects the cost of drugs, the cost of all resources expended in patient management such as the cost of disposables for each infusion, the monitoring costs during infusion (salaries of personnel), other hospital expenses, the cost for management of adverse events, the productivity loss, and the traveling cost for patients.Results: In the case of outpatients, the mean total cost per patient in the FCM arm was &euro;198.6, in the IS arm &euro;627.7, and in the LMWID arm, &euro;510.5. For inpatients the mean total cost was estimated at &euro;189.2 for FCM while it was &euro;419.9 and &euro;228.8 for IS and LMWID, respectively. Budget impact analysis for a typical Greek hospital with 100 patients revealed that the total cost of FCM (inpatients analysis) was 113% and 15.4% lower against their comparators. In an outpatient situation, the total cost of FCM was 201.1% and 151.8% lower compared with IS and LMWID, respectively.Conclusion: Ferric carboxymaltose may represent a cost-saving option compared with the most likely alternative existing therapies used for the management of anemia in the National Health Service of Greece.Keywords: economic evaluation, cost minimization, ferric carboxymaltose, anemia, iron therap
