84 research outputs found
The clinical utility of 99(m)Tc-HMPAO SPECT in Fahr's disease
No full textFahr's disease is a rare neurodegenerative syndrome, characterized by massive symmetrical intracerebral calcifications of the basal ganglia, dentate nuclei of the cerebellum, and the adjacent parenchyma. Computerized tomography (CT) is considerably more sensitive to detect these intracranial calcifications than other imaging modalities. The clinical, CT scan, and 99(m)Tc-D,L-hexamethylpropylene amine oxime (99(m)Tc-HMPAO) brain perfusion single-photon emission computerized tomography (SPECT) findings in a 42-year-old woman with Fahr's disease are reported, and the clinical utility of 99(m)Tc-HMPAO SPECT findings in Fahr's disease is discussed in this article. In conclusion, 99(m)Tc-HMPAO brain perfusion SPECT seems to be useful in the clinical approach to Fahr's disease, and may provide more specific and clinically relevant information when compared with anatomical imaging
Intensive care costs of acute poisoning cases
No full textAim. To examine the costs of acute poisoning patients admitted to an intensive care unit. Methods. Retrospective review of intensive care unit records of patients admitted for treatment of acute poisoning from January 1, 2002 to September 30, 2006. Results. The study group consisted of 94 patients and 18.1 % of them died in the intensive care unit. The 62 suicidal cases were significantly younger than the accidental cases (p = 0.006). The average cost per intensive care unit stay was US 711 +/- 695 for suicidal and US $1,036 +/- 1,713 for accidental cases). Conclusions. Poisoned patients admitted to an intensive care unit represent a considerable cost for the health care system in Turkey
Intensive care cost and survival analyses of traumatic brain injury
No full textBACKGROUND Intensive care of Traumatic Brain Injury (TB!) is associated with substantial morbidity, mortality and cost; however, there is very little published work on this topic. The purpose of this study was to examine direct costs and survival outcomes of patients with TBI admitted to an intensive care unit (ICU). METHODS A retrospective review of the records of Trakya University Hospital's ICU from 2002-2006 was undertaken. Patients with TBI were determined and assessed regarding costs and survival. RESULTS The study group consisted of 126 patients, and 27.8% of them had been operated. Male gender (80.2%) was dominant, mean length of stay was 9.8 +/- 8.7 days, and motor vehicle injury (59.5%) was the major reason for ICU admission. Mortality rate was 50% and the Glasgow Coma Score (GCS) of the patients was 6.1 +/- 1.9. The average cost per ICU stay was US 313.60, respectively. Survival rates were significantly different among injury types (p=0.010). GCS appeared to be a prognostic parameter in patient survival (Hazard Ratio: 0.643; 95%CI: 0.529-0.781; p<0.001). CONCLUSION Intensive care of TBI cases is characterized by high mortality and high cost
Role of Bacteriological Agents in Idiopathic Granulomatous Mastitis: Real or Not?
No full textKartal, Abdulcabbar/0000-0001-7536-3146; Dikicier, Enis/0000-0002-5074-0299; ferhatoglu, m ferhat/0000-0003-1520-7517; Dilek, Fatma Hüsniye/0000-0003-0074-6593; Dikicier, Enis/0000-0002-5074-0299;Objective: Granulomatous mastitis is a rare, benign, chronic inflammatory disease of the breast of unknown etiology. This study evaluated bacteriologic agents that might play a role in the etiology of granulomatous mastitis using a molecular method with a universal primer after isolating deoxyribonucleic acid (DNA) from pathology specimens from patients diagnosed with granulomatous mastitis. Materials and Methods: Breast biopsy material in the pathology department obtained between July 2008 and June 2013 was analyzed. The history of the granulomatous mastitis patients was examined in detail and paraffin block sections of the biopsy material were used to determine the presence of bacteria with a universal DNA primer. Results: This study examined 45 granulomatous mastitis patients who had been diagnosed using excisional, incisional, or core biopsies. We evaluated multiple bacterial taxa, but obtained no positive result using a nucleic-acid-based assay with a universal primer. Conclusion: The etiology of idiopathic granulomatous mastitis remains unclear. Further studies with a large number of patients should aim to identify the causative agent
Erratum to: The influence of N-acetyl-L-cysteine infusion on cytokine levels and gastric intramucosal pH during severe sepsis
No full text[Abstract Not Available
Indomethacin-Induced Pancreatitis: A Case Report
No full textContext There are no previous reports of acute pancreatitis associated with the use of indomethacin in the general population. Drugs of all types are related to the etiology of pancreatitis in approximately 1.4-2.0% of cases. Case report We report the case of a 56-year-old man who presented with acute pancreatitis after a period of indomethacin therapy. Other causes of the disease were ruled out. Due to multiorgan failure, he was in the intensive care unit for 44 days. He made a full recovery. The indomethacin was discontinued. Conclusions We report indomethacin as the probable cause of acute pancreatitis in a patient without any known predisposing factors. To our knowledge, this is the rare description of a case of indomethacin-induced pancreatitis. However, the link is difficult to establish and further evidence is required to prove the association
The Preoperative use of gabapentin, dexamethasone, and their combination in varicocele surgery
No full textBACKGROUND: We investigated the effects of gabapentin and dexamethasone given together or separately 1 h before the start of surgery on laryngoscopy, tracheal intubation, intraoperative hemodynamics, opioid consumption, and postoperative pain in patients undergoing varicocele operations. METHODS: Patients were randomly divided into four double-blind groups: group C (control, n = 20) received placebo, group G (gabapentin, n = 20) received 800 mg gabapentin, group D (dexamethasone, n = 20) received 8 mg dexamethasone, group GD (gabapentin plus dexamethasone) received both 800 mg gabapentin and 8 mg dexamethasone IV 1 h before the start of surgery. Standard induction and maintenance of anesthesia were accomplished and continued by propofol and remifentanil infusion. Heart rate and arterial blood pressure were recorded before induction and after intubation. Intraoperative total remifentanil consumption was recorded. Hemodynamic variables and visual analog scale were recorded RESULTS: Hemodynamics at 1, 3, 5, and 10 min after tracheal intubation, total remifentanil consumption during surgery, postoperative visual analog scale scores at 30 min, 1, 2, 4, 6, and 12 h, and postoperative nausea and vomiting were found to be significantly lower in group GD than in group G and group D (P < 0.05 for both), and substantially lower when compared with group C (P < 0.001). All values in group C were also higher than in groups G and D (P < 0.05). CONCLUSION: Gabapentin and dexamethasone administered together an hour before varicocele surgery results in less laryngeal and tracheal intubation response, improves postoperative analgesia, and prevents postoperative nausea and vomiting better than individual administration of each drug
Primary lymphoma of the mandible. Report of a case
No full textHighlights of Quark Matter 95 are discussed
Evaluation of the prognostic value of plasma clearance rate of indocyanine green and Pitt bacteremia score in patients with sepsis
No full textObjective: Sepsis is frequently seen in intensive care unit patients, representing an important cause of mortality. Prediction of prognosis in patients with sepsis is of particular importance. We investigated the relationship of plasma clearance rate of indocyanine green (ICG-PDR) and Pitt bacteremia score with prognosis in sepsis. Materials and methods: We retrospectively evaluated 100 patients whose ICG-PDR values were measured noninvasively with the LiMON system and Pitt bacteremia scores were determined within the first 24 hours of admission to intensive care unit. All the patients were diagnosed with sepsis before receiving intensive care. ICG-PDR values and Pitt bacteremia scores were compared between patients who died (n=48; mean age 62.4 16.5 years) or survived (n=52; mean age 60.8 +/- 18.2 years) during intensive care stay. Results: Compared to survivors, the mean ICG-PDR was significantly lower (21.1 +/- 5.4%/min vs. 13.9 +/- 6.4 %min; p<0.001) and the mean Pitt bacteremia score was significantly higher (4.9 +/- 2.0 vs. 10.2 +/- 1.7; p=0.000) in patents who died during intensive care treatment. In ROC analysis, the area under the curve was 0.819 for ICG-PDR, and 0.955 for Pitt bacteremia score. The optimal cut-off points for ICG-PDR and Pitt bacteremia score were 14.8%/min and 7, respectively. ICG-PDR and Pitt bacteremia score predicted mortality with a sensitivity of 75% and 97.9%, and specificity of 92.3% and 92.3%, respectively. Conclusion: Our findings show that both ICG-PDR and Pitt bacteremia score are effective markers in predicting survival of patients with sepsis and can be used in the evaluation of disease severity
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