178,620 research outputs found
Graphene q-switched Yb: phosphate glass channel waveguide laser
No full textQ-switched lasers can generate high-energy pulses that can have applications in medicine, material processing and defence. Waveguide lasers have several attractive features such as a low laser threshold and a high slope efficiency, provided that the propagation losses are kept low, compactness and mass-producibility. Ion-exchange is a simple and cheap technique to fabricate loss-loss waveguides in glass, with mode-locked operation being demonstrated in ion-exchanged Yb:phosphate glass lasers using a semiconductor saturable absorber mirror (SESAM). Using graphene as a saturable absorber has several key advantages over SESAMs such as a broad wavelength operating range, cost-effectiveness and ease of fabrication. Graphene has previously been used as a saturable absorber to demonstrate Q-switched mode-locking in a femtosecond-written glass waveguide laser and Q-switched operation in a carbon-irradiated Nd:YAG ceramic channel waveguide laser. In this paper we present an ion-exchanged Yb:phosphate glass waveguide laser, Q-switched using a graphene saturable absorber
Identification of novel biomarkers for thyroid cancer using multi omics data analysis
No full textThe biomarkers for thyroid cancer are still not known properly. For treating thyroid cancer these biomarkers can by be targeted specifically. Through this project, we identified and used bioinformatics tools to find biomarkers associated with thyroid cancer. Gene Expression Omnibus database (GEO) was used to find dataset related with thyroid cancer. Their expression profiles were downloaded. Four dataset GSE3467, GSE3678, GSE33630, and GSE53157 were identified from GEO database. The dataset GSE3467 contains nine thyroid tumor samples and nine normal thyroid tissue samples. The GSE3678 contains seven thyroid tumor samples and seven normal thyroid tissue samples. The GSE53157 contains twenty four thyroid tumor samples and three normal thyroid samples. The GSE33630 contains sixty thyroid tumor samples and forty five normal thyroid samples. These four datasets were analyzed individually and were integrated at the end to find the common genes among these four datasets. The microarray analysis of the datasets were performed using excel. T.Test analysis were performed for all the four datasets individually on a separate excel sheet. The data was normalized by converting normal value into log scale. Differential expression analysis of all the four datasets were done to identify differentially expresses genes (DEGs). Only upregulated genes were taken into account. Principal component analysis (PCA) of all the four dataset were performed using the raw data. The PCA analysis were performed using T-BioInfo server and the scatterplots were prepared using excel. RStudio was used to match the gene symbols with the corresponding probe ids using left join function. Inner join function in R was used to find integrated genes between the four datasets. Heatmaps of all the four datasets were performed using RStudio. To find number of intersection of Differentially expressed genes, an upset plot was prepared using RStudio. 74 genes with their corresponding probe ids were found to be common among all the four datasets. These genes are common to at least two datasets. These 74 common genes were analyzed using Database for Annotation, Visualization, and Integrated Discovery (DAVID), to study their Gene onotology (GO) functional annotations and pathways. According to the GO functional annotations result, most of the integrated upregulated genes were involved in protein binding, plasma membrane and integral component of membrane. Most common pathway include Extracellular matrix organization, Neutrophil degranulation, TGF-beta signaling pathway and Epithelial to mesenchymal transition in colorectal cancer. These 74 genes were introduced to STRING database to find protein-protein interactions between the genes. Interactions between the nodes were downloaded from STRING database and introduced to Sytoscape. Sytoscape analysis explained that only 19 genes showed protein-protein interactions between each other. Disease free survival analysis of the 13 genes that were common to three datasets were done using GEPIA. Boxplots of these 13 genes were also prepared using GEPIA. This showed that these differentially expressed genes showed different expression in normal thyroid tissue and thyroid tumor samples. Hence these 13 genes common to 3 datasets can be used as potential biomarkers for thyroid cancer. Among these 13 genes, four genes are implicated in cancer/cell proliferation can be probable target for treatment options
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Letter from R. R. Zellick, Assistant Trust Officer, Anglo California National Bank of San Francisco, to Joseph R. Goodman, October 2, 1942
No full textLetter from R. R. Zellick, Assistant Trust Officer at The Anglo California National Bank of San Francisco, to Joseph R. Goodman, regarding property owned by Dave Tatsuno. Zellick mentions a dispute between current tenants and Tatsuno, and that Tatsuno has asked Goodman to help locate trustworthy tenants.Personal correspondence, organizational records, government documents, publications, and other papers created or collected by Joseph R. Goodman documenting the forced removal and incarceration of Japanese Americans during World War II, as well as organized resistance to incarceration. Included in the collection are records of the Japanese Young Men's Christian Association and the Japanese American Citizens' League in San Francisco, including papers of the Japanese YMCA's executive secretary Lincoln Kanai; Sakai family papers; Goodman's correspondence to and from Japanese American incarcerees, organizations opposing forced removal and incarceration of Japanese Americans, the War Relocation Authority, and others; publications, photographs, and ephemera from the Topaz Relocation Center, where Goodman taught high school; War Relocation Authority records and publications; and newspaper clippings, pamphlets, and reports about forced removal and incarceration created by various government, religious, and civic organizations, in California and nationwide
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Figure 2 in Rhipicephalus (Boophilus) microplus (Arachnida: Ixodidae) larvae infestation of human eyelids. A rare case
No full textFigure 2 Larvae of R. (B.) microplus.Published as part of <i>Kaur, Navpreet, Prasher, Pawan, Kumar, Khushhal & Dhingra, Sakshi, 2019, Rhipicephalus (Boophilus) microplus (Arachnida: Ixodidae) larvae infestation of human eyelids. A rare case, pp. 21-25 in Acarologia 59 (1)</i> on page 23, DOI: 10.24349/acarologia/20194309, <a href="http://zenodo.org/record/4502839">http://zenodo.org/record/4502839</a>
Liftings for noncomplete probability spaces
No full textThe current state of knowledge concerning liftings for noncomplete probability spaces is discussed. This is a somewhat expanded version of the author's talk given at the 1991 Summer Conference on General Topology and Applications in Honor of Mary Ellen Rudin and Her Work.PT: S; CR: BURKE MR, IN PRESS P AM MATH S BURKE MR, 1991, ISRAEL J MATH, V73, P33 BURKE MR, 1992, ISRAEL J MATH, V79, P289 CARLSON T, THEOREM LIFTING CHRISTENSEN JPR, 1974, TOPOLOGY BOREL STRUC FREMLIN DH, 1989, HDB BOOLEAN ALGEBRAS, P877 INOESCUTULCEA A, 1966, 5TH P BERK S MATH ST, V2 IONESCUTULCEA A, 1967, CONTRIBUTIONS PROB 1, P63 IONESCUTULCEA A, 1969, TOPICS THEORY LIFTIN JECH TJ, 1978, SET THEORY JOHNSON RA, 1980, P AM MATH SOC, V80, P234 JUST W, IN PRESS T AM MATH S KUPKA J, 1983, INDIANA U MATH J, V32, P717 LOSERT V, 1983, LNM, V1080, P95 MAHARAM D, 1958, P AM MATH SOC, V9, P987 SHELAH S, 1983, ISRAEL J MATH, V45, P90 TALAGRAND M, 1982, P AM MATH SOC, V84, P379 VONNEUMANN J, 1931, CRELLES J MATH, V165, P109; NR: 18; TC: 0; J9: ANN N Y ACAD SCI; PG: 4; GA: BZ86BSource type: Electronic(1
Hansen, Lee (Lee R.). Union, non-union, and managerial pay plan state employees, 2008-2019
No full text1 online resource (2 pages)"July 1, 2021."Provides the number of union and non-union state employees in each of the last 14 years. Also provides the number of state employees paid under the state's managerial pay plan during each of those years. Updates OLR research report 2019-R-011
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