131 research outputs found
BUKTI SEBAGAI KORESPONDING AUTHOR PADA JURNAL 2 OK-Roni Pazla
No full textBUKTI SEBAGAI KORESPONDING AUTHOR PADA JURNAL 2 O
Integrating TRPV1 Receptor Function with Capsaicin Psychophysics
No full text© 2016 Gregory Smutzer and Roni K. Devassy. Capsaicin is a naturally occurring vanilloid that causes a hot, pungent sensation in the human oral cavity. This trigeminal stimulus activates TRPV1 receptors and stimulates an influx of cations into sensory cells. TRPV1 receptors function as homotetramers that also respond to heat, proinflammatory substances, lipoxygenase products, resiniferatoxin, endocannabinoids, protons, and peptide toxins. Kinase-mediated phosphorylation of TRPV1 leads to increased sensitivity to both chemical and thermal stimuli. In contrast, desensitization occurs via a calcium-dependent mechanism that results in receptor dephosphorylation. Human psychophysical studies have shown that capsaicin is detected at nanomole amounts and causes desensitization in the oral cavity. Psychophysical studies further indicate that desensitization can be temporarily reversed in the oral cavity if stimulation with capsaicin is resumed at short interstimulus intervals. Pretreatment of lingual epithelium with capsaicin modulates the perception of several primary taste qualities. Also, sweet taste stimuli may decrease the intensity of capsaicin perception in the oral cavity. In addition, capsaicin perception and hedonic responses may be modified by diet. Psychophysical studies with capsaicin are consistent with recent findings that have identified TRPV1 channel modulation by phosphorylation and interactions with membrane inositol phospholipids. Future studies will further clarify the importance of capsaicin and its receptor in human health and nutrition
Rewriting our comments and revisiting revision practices: new concepts for sustainable instruction in the writing classroom
No full textThe driving instructional tool in the majority of writing classrooms, comments, is failing students and instructors because comments are a tool, and not a technique. The utility of comments within the writing classroom is only as strong as its pairing with other instructional techniques. Using comments to teach comments is a flawed method of instruction, and if instructors want to properly use comments within their classes, they must first show their students how to use these techniques in improving their writing. Thus far, the focus of facilitating student revision and student growth within writing classrooms has been on the study of specific comments written by instructors on student papers. The study of such comments reveals the differences in styles, modes, and voices projected from those instructors, but it does reveal much about the intended goal of such comments, the advancement of student writing. Looking back on previous research and incorporating a multifaceted approach to revision helps to build sustainable writing instruction. A review of literature of comments suggests placing students in the center of the classroom by enabling students to take control over the revisions of their own work. This process cannot be done without teaching students how to do things with comments and how to use comments to their advantage. Starting from Joseph Harris’ Rewriting, the same steps toward revision which Harris suggests of students should be copied and applied to the way in which instructors facilitate such revision within the classroom. The improvement of student writing requires several steps which target particular issues with the status quo of commenting, and the use of Harris’ text will enable us to identify the steps. Incorporating revision into the classroom, inviting students into conversation about their text, and opening the lines of communication can help improve revision practices in writing classrooms. Through incorporating a new mastery model within the writing classroom, a technique that begins to show students how comments are made and what to do with them, students can begin to internalize the many processes which they can apply to any writing. The teacher’s goal is to help the student internalize the concepts and apply without the direct instruction of the teacher; however, many writing classrooms have lost this focus. If teachers refocus the classroom on the process of writing and even the process of editing and revising, students will become not just stronger students but writers. Adjustments in the writing classroom cannot occur overnight, but incorporating revision techniques into the course will eventually pay off as students learn to revise their work. These techniques, although not new, can prepare students for writing outside the composition classroom.M. A.Includes bibliographical referencesby Roni L. Bie
Dialettica della durata e vita intima. Attualità di Bergson tra accelerazione del tempo e alienazione sociale
No full textIn this paper the Author focuses on the legacy of dialectics through Bergson’s considerations about time and language, recalling two great interpreters of his philosophy: Giuseppe Prezzolini and Gaston Bachelard. If for the former the «philosophy of contingency» enhances the transformation of social reality, preserving, in consonance with Victor Egger’s
book La parole intérieure, the freedom of inner language, the latter proposes a break of the Bergsonian temporal continuity by opting for a plural and discontinuous duration. Thanks to these readings, it is possible to discover the temporal dialectic which regulates contemporary societies, that is, the acceleration of time and the contraction of memory, in order to develop a more humane way of living time and, consequently, to decline the problem of intersubjectivity in an intercultural perspective
Leon Garfield
No full textThrough his historical novels, adventure stories, ghost stories, satires, fairy tales, and retellings of myths and legends, Leon Garfield consistently portrays the mystery of human identity, which he describes as "the only mystery one can unravel endlessly." In this first book-length study of the author of Smith (1967), The Apprentices (1976), John Diamond (1981), and The December Rose (1986), Roni Natov engagingly chronicles the career of a natural storyteller, a man whose work is permeated with the theme of spiritual renewal
Young generations’ hopelessness perpetuates long-term conflicts
No full textFunding Information: The authors would like to thank Roni Porat for their valuable contribution in the conceptualization stage of the research, and Shir Harpaz, Natali Afrimov, and Dan Heskia for their assistance in the data analysis. This work was supported by an Israel Science Foundation Grant (3105/21) to the first author (BSH). Funding Information: The authors would like to thank Roni Porat for their valuable contribution in the conceptualization stage of the research, and Shir Harpaz, Natali Afrimov, and Dan Heskia for their assistance in the data analysis. This work was supported by an Israel Science Foundation Grant (3105/21) to the first author (BSH). Publisher Copyright: © 2023, The Author(s).Transforming long-term conflicts into peaceful intergroup relations is one of the most difficult challenges for humanity. Such meaningful social changes are often driven by young people. But do young people living in contexts of long-term conflicts believe that change is even possible? In a series of six studies (Ntotal = 119,671) over two decades and across two unrelated intractable conflicts in Israel/Palestine and Cyprus, we found that younger (compared to older) generations from both respective rival groups have less hope for peace, and consequently less conciliatory attitudes. We also show that this gradual improvement of peace-promoting emotions and attitudes with increasing age can be experimentally accelerated in young people through a virtual reality-based aging simulation. These findings provide a new perspective on the fundamental question of why long-term conflicts are so difficult to resolve and highlight the importance of instilling hope in young generations to advance peace processes.Peer reviewe
Integrating TRPV1 Receptor Function with Capsaicin Psychophysics
No full textCapsaicin is a naturally occurring vanilloid that causes a hot, pungent sensation in the human oral cavity. This trigeminal stimulus activates TRPV1 receptors and stimulates an influx of cations into sensory cells. TRPV1 receptors function as homotetramers that also respond to heat, proinflammatory substances, lipoxygenase products, resiniferatoxin, endocannabinoids, protons, and peptide toxins. Kinase-mediated phosphorylation of TRPV1 leads to increased sensitivity to both chemical and thermal stimuli. In contrast, desensitization occurs via a calcium-dependent mechanism that results in receptor dephosphorylation. Human psychophysical studies have shown that capsaicin is detected at nanomole amounts and causes desensitization in the oral cavity. Psychophysical studies further indicate that desensitization can be temporarily reversed in the oral cavity if stimulation with capsaicin is resumed at short interstimulus intervals. Pretreatment of lingual epithelium with capsaicin modulates the perception of several primary taste qualities. Also, sweet taste stimuli may decrease the intensity of capsaicin perception in the oral cavity. In addition, capsaicin perception and hedonic responses may be modified by diet. Psychophysical studies with capsaicin are consistent with recent findings that have identified TRPV1 channel modulation by phosphorylation and interactions with membrane inositol phospholipids. Future studies will further clarify the importance of capsaicin and its receptor in human health and nutrition
Island zombie Iceland writings
No full text"Roni Horn (b. 1955) is a prominent contemporary artist known for her sculptures, photography, and installations inspired by landscape and the natural world, and especially the isolated landscapes of Iceland, where she has travelled and lived for substantial periods of time since the early 1970s. Horn's work explores geology and climate; the interplay of nature, art, and place; and the relationships between words, appearance, androgyny, and the self. Horn is author of more than twenty books and artist's books, and is herself the subject of more than thirty books and exhibition catalogs, including a survey published by Phaidon and many by Steidl. Examples of her work include You Are the Weather (1994-96), a series of photographs of a young woman bathing in Icelandic hot springs; Pair Objects (1988), identical metal sculptures placed in two different locations; and the installation Library of Water (2007) in Iceland, with columns that enclose water from melting glaciers. Horn is arguably the most important visual chronicler of the landscape of Iceland. Upon graduating from her MFA program at Yale, she traveled to Iceland, journeying across its interior on a motorcycle. Over thirty years, she has continually returned to Iceland to explore and record the astonishing beauty of its geology, climate, and culture. This book will contain a range of texts, from evocative vignettes to illustrated essays written for Iceland's most widely-read newspaper. A combination of artists' writings and travelogue, the texts reveal Iceland as one of Horne's most important influences and inspirations, and record a unique and beautiful environment undergoing climate change"-
A circle of salt
No full textMy dissertation project is a novel. The year is 1986, and the setting alternates between the small, isolated town of Eudora, Alabama, and Birmingham, that sprawling industrial city founded after the Civil War. The main character, Roni, short for Veronica Silvering, is the only daughter of Sadie Silvering, a backwoods Alabama mystic and healer, of sorts. The supernatural powers that Sadie exhibits are passed down only through the maternal line of families, from mothers to daughters. The central conflict of the novel lies in the fact that Sadie wants Roni to continue her mother’s work as a healer after she dies, but Roni has already determined the path her own life will take. Roni is independent and, at the age of 22, is already busy at work creating a future for herself as an artist, far removed from the culture and landscape of her childhood. Tension results from the consistent tug that Roni feels toward the life created for her by her mother and the life she has envisioned for herself.Embargo status: Restricted until 06/2162. To request the author grant access, click on the PDF link to the left
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