455 research outputs found
Food for nought
No full textThe short story, "Food for nought", is written by the listed author above, Shashi Bhat. Now in its 48th year, Best Canadian Stories has long championed the short story form and highlighted the work of many of the writers, throughout their respective careers, who have gone on to shape the Canadian literary canon. Caroline Adderson, Margaret Atwood, Clark Blaise, Lynn Coady, Mavis Gallant, Zsuzsi Gartner, Douglas Glover, Steven Heighton, Isabel Huggan, Mark Anthony Jarman, Norman Levine, Rohinton Mistry, Alice Munro, Leon Rooke, Diane Schoemperlen, Russell Smith, Linda Svendsen, Kathleen Winter, and many others have appeared in its pages over the years and decades, making Best Canadian Stories the go-to source for what’s new in Canadian fiction writing for close to five decades. A continuation of not only a series, but a legacy in Canadian letters. --From publisher description.Published
TWO NEW SPECIES OF POACEAE FROM INDIA
No full textTwo new species of Poaceae namely, Erayrostis santapaui K. G. Bhat & C. R. Nagendran and Chrysopogon pseitdozeylanicus K. G. Bhat & C. R. Nagendran have been described from materials collected by the senior author from Coorg- and South Kanara Districts of Karnataka State, India
Fish distribution dynamics in the Aghanashini estuary of Uttara Kannada, west coast of India
No full textFish diversity (77 species) in the Aghanashini River estuary of the Indian west coast is linked to variable salinity conditions and zones I, II and III for high, medium and low salinity respectively. Zone I, the junction between Arabian Sea and the estuary, had all species in yearly succession due to freshwater conditions in monsoon to high salinity in pre-monsoon. The medium (zone II) and low (zone III) salinity mid and upstream portions had maximum of 67 and 39 fish species respectively. Maintenance of natural salinity regimes in estuary, among other ecological factors, is critical for its fish diversity
Neuropeptide VGF Promotes Maturation of Hippocampal Dendrites That Is Reduced by Single Nucleotide Polymorphisms
No full textThe neuropeptide VGF (non-acronymic) is induced by brain-derived neurotrophic factor and promotes hippocampal neurogenesis, as well as synaptic activity. However, morphological changes induced by VGF have not been elucidated. Developing hippocampal neurons were exposed to VGF through bath application or virus-mediated expression in vitro. VGF-derived peptide, TLQP-62, enhanced dendritic branching, and outgrowth. Furthermore, VGF increased dendritic spine density and the proportion of immature spines. Spine formation was associated with increased synaptic protein expression and co-localization of pre- and postsynaptic markers. Three non-synonymous single nucleotide polymorphisms (SNPs) were selected in human VGF gene. Transfection of N2a cells with plasmids containing these SNPs revealed no relative change in protein expression levels and normal protein size, except for a truncated protein from the premature stop codon, E525X. All three SNPs resulted in a lower proportion of N2a cells bearing neurites relative to wild-type VGF. Furthermore, all three mutations reduced the total length of dendrites in developing hippocampal neurons. Taken together, our results suggest VGF enhances dendritic maturation and that these effects can be altered by common mutations in the VGF gene. The findings may have implications for people suffering from psychiatric disease or other conditions who may have altered VGF levels.Peer reviewe
Développement d'alliages à base de magnésium pour applications biomédicales
No full textÉtant donné leur capacité à se dégrader à l'intérieur du corps, les implants biodégradables ont fait l'objet de nombreuses recherches médicales. Parmi tous les matériaux, c'est le magnésium, un élément indispensable du corps humain, qui conduit aux résultats les plus favorables car son module d'Young est similaire à celui de l'os. De ce fait, les méthodes adoptées afin d'améliorer le comportement du magnésium pur vis-à-vis de la corrosion sont les suivantes: a)Ajout d'éléments d'alliage comme le zinc, le calcium et l'erbium (Mg-2Zn-2Er, Mg-2Zn-0.6Ca-1Er, etc.) pour contrôler le comportement de dégradation b) Procédés secondaires tels que l'extrusion pour modifier sa microstructure c)Revêtements de surface à base de fluorure pour mieux protéger la surface. La première partie de cette thèse porte sur la caractérisation microstructurale d'alliages. La caractérisation microstructurale révèle la présence de MgZn2, de phases W (Mg3Zn3Er2) et i (Mg3Zn6Er) dans différents alliages. L'évaluation des propriétés mécaniques a révélé une augmentation des propriétés de traction et de compression des alliages ternaires et quaternaires par rapport aux alliages de Mg et de Mg-2Zn. Ces propriétés mécaniques améliorées sont attribuées à une réduction de la taille des grains, à la présence d'atomes de soluté et à des phases secondaires. Mg-2Zn-2Er et Mg-3Zn-0.5Er présentaient une résistance à la corrosion améliorée en raison de la microstructure à granulométrie fine et d'une répartition uniforme des phases secondaires. La viabilité cellulaire a été améliorée avec l'épaisseur du temps de revêtement et ces alliages pourraient servir de candidats potentiels pour d'autres tests in vivo.With the ability to bio-degrade and thereby reducing the stress-shielding effect, biodegradable implants are of great importance in medical research. Among all the materials, magnesium is the one which shows promising results being bio-degradable and with the properties comparable with its young's modulus to that of bones. In the present study, the approaches adopted to improve the mechanical and corrosion behaviors of pure magnesium using carefully chosen: (a) Alloying elements like zinc, calcium and erbium (Mg-2Zn-2Er, Mg-2Zn-0.6Ca-1Er, etc.) to control the degradation behavior (b) Secondary processes like extrusion to alter and improve the microstructure (c) Surface treatments like fluoride coatings to further protect the surface to resist the rapid dissolution. The first part of this thesis focuses on the microstructural characterization of as-DMDed and as-extruded alloys. The microstructural characterization (XRD and TEM) reveals the presence of MgZn2, W-phase (Mg3Zn3Er2) and i-phases (Mg3Zn6Er) in different alloys. The mechanical property assessment revealed an increment in the tensile and compressive properties of ternary and quaternary alloys as compared to pure Mg and Mg-2Zn binary alloy. These values are attributed to a reduction in grain size, presence of solute atoms and secondary phases. Mg-2Zn-2Er and Mg-3Zn-0.5Er showed enhanced corrosion resistance due to the fine grain sized microstructure and a uniform distribution of secondary phases. The cell viability values were enhanced with increased coating time and it was found that these alloys could serve as potential candidates for further in-vivo tests to establish their applicability
Addressing critical adjacencies in Mumbai's urban farm
No full textThesis (S.M.)--Massachusetts Institute of Technology, Dept. of Architecture, 2008.Includes bibliographical references (p. 99-101).This thesis focuses on the city of Mumbai, and evolves the notion of how "critical adjacency" has been instrumental in guiding the city's urban transformations into modernity. Presently, Mumbai experiences some of the highest densities and land value Levels in the world, and the city still continues to grow. New development in the city often involves the displacement of slum dwellers to the periphery of the city, or further diffuses them into obscure interstices of the urban fabric. This thesis takes an ethical stance which calls for the reincorporation of these "slum publics" back into the fold of the central city by experimenting with manipuLations of adjacency and grain at the urban and architectural scale. The expectation of the thesis is that through tactical collisions of multiple socio-economic publics, new commercial development can serve both top down and bottom up modes of modernization.Arjun Bhat.S.M
Fabrication of nanoadjuvant with poly-ɛ-caprolactone (PCL) for developing a single-shot vaccine providing prolonged immunity [Corrigendum]
No full textPrashant CK, Bhat M, Srivastava SK, et al. Int J Nanomedicine. 2014;9:937–950.On page 937, the author affiliations have been listed incorrectly. The correct author list is as follows:Chandravilas Keshvan Prashant1Madhusudan Bhat2Sandeep Kumar Srivastava2Ankit Saxena3Manoj Kumar4Amar Singh3Mohammed Samim5Farhan Jalees Ahmad6Amit Kumar Dinda21Faculty of Engineering and Interdisciplinary Sciences, Jamia Hamdard, New Delhi, India; 2Department of Pathology, 3Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India; 4Centre for Biomedical Engineering, Indian Institute of Technology, New Delhi, India; 5Department of Chemistry, Faculty of Science, Jamia Hamdard, New Delhi, India; 6Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, New Delhi, IndiaRead the original articl
Corrosion Behavior, Microstructure and Mechanical Properties of Novel Mg-Zn-Ca-Er Alloy for Bio-Medical Applications
No full textIn this study, the effect of calcium (Ca) and erbium (Er) on the microstructure, mechanical properties, and corrosion behavior of magnesium-zinc alloys is reported. The alloys were prepared using disintegrated melt deposition (DMD) technique using the alloying additions as Zn, Ca, and Mg-Er master alloys and followed by hot extrusion. Results show that alloying addition of Er has significantly reduced the grain sizes of Mg-Zn alloys and also when compared to pure magnesium base material. It also has substantially enhanced both the tensile and the compressive properties by favoring the formation of MgZn2 type secondary phases that are uniformly distributed during hot-extrusion. The quaternary Mg-Zn-Ca-Er alloy exhibited the highest strength due to lower grain size and particle strengthening due to the influence of the rare earth addition Er. The observed elongation was a result of extensive twinning observed in the alloys. Also, the degradation rates have been substantially reduced as a result of alloying additions and it is attributed to the barrier effect caused by the secondary phases
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