1,720,969 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Unveiling Anticancer Potential in the Interactions of Melittin Peptides with CD147 Receptor: A Structural and Functional Analysis of Ligand-Target Interactions
No full textIn this study, the anticancer potential of melittin (MLT) peptides interacting with the CD147 receptor was investigated through in silico structural and functional analyses. The interaction between the transmembrane glycoprotein CD147 and cyclophilin A (CypA) activates signaling pathways crucial in cancer pathology. This study focused on the potential of melittin peptides to inhibit this interaction. Structures of the CD147 receptor and melittin peptides were obtained from the Protein Data Bank (PDB), including the three-dimensional structure of the Ig1 domain of CD147 (PDB ID:5XF0) and melittin structures (PDB IDs:2MLT, 6O4M, 3QRX, 8AHT, and 8AHS). Validated ligand structures were acquired through X-ray crystallography. Receptorligand interactions and anticancer activity were evaluated using the ClusPro2.0 molecular docking server, AnciCP2.0 and ENNAACT anticancer analysis servers, ProtScale hydrophobicity analysis, PDBSum amino acid interaction analysis, and PRODIGY thermodynamic stability analysis tools. Molecular docking simulations analyzed receptor-ligand interactions, emphasizing the role of hydrophobic interactions. Structural analysis revealed variability in peptide quality, with 2MLT demonstrating favorable attributes while 3QRX exhibited weak integrity. Anticancer analysis servers indicated that 2MLT and 3QRX, exhibiting similar binding patterns with 5XF0 and CD147/CypA, may demonstrate potential anticancer activity. Specifically, non-bonded interactions involving Gly181 and Arg201 in the 5XF0-2MLT complex and non-bonded interactions involving Pro180, Gly181, and Arg201 in the 5XF0-3QRX complex were highlighted, resembling the interaction pattern of CD147/CypA. Therefore, the importance of understanding molecular interactions and guiding drug discovery through structural examinations and computational analyses was emphasized, providing insights into the anticancer effects and drug design implications of these complexes; moreover, further research into their structural determinants and therapeutic potentials is critically essential for biomedical applications
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
MELİTTİN'İN CD147 İLE ETKİLEŞİMİNE YAPISAL BAKIŞ VE ANTİKANSER POTANSİYELİ
Get PDFObjective: This study investigates the interaction between melittin (PDB ID: 2MLT), a bioactive peptide from honeybee venom, and CD147 (PDB ID: 5XF0), a glycosylated transmembrane protein implicated in tumor progression. Material and Method: Employing molecular docking and bioinformatics tools, our structural analysis reveals diverse binding features, including hydrogen bonds, salt bridges, and non-bonded contacts, between the CD147 complex and melittin. Result and Discussion: Non-bonded interactions between 2MLT and specific amino acids (Gly181 and Arg201) of CD147 are highlighted, resembling aspects of the CypA/CD147 binding mechanism (Pro180-Gly181 and Arg201). The elevated anticancer potential of 2MLT was substantiated by utilizing the AntiCP 2.0 server and the ENNAACT server, employing machine learning and artificial neural network algorithms. Additionally, hydrophobicity analysis aligns with characteristics associated with anticancer peptides. Notably, thermodynamic stability variations with temperature underscore the robust binding affinity of 2MLT to the 5XF0 receptor. While our study comprehensively explores molecular interactions and predictive analyses, further in vitro and in vivo investigations are crucial to validate these findings for potential therapeutic applications. © 2024 University of Ankara. All rights reserved
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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