1,544 research outputs found
Active-template synthesis of small functionalised rotaxanes for sensing applications
No full textInterlocked molecules, the archetypal examples of which are catenanes, and rotaxanes, have progressed over the last half-century from a significant synthetic challenge to readily accessible chemical species. The interest for these supramolecular architectures, which started from a purely aesthetic point of view, has further developed due to the high degree of freedom between its individual components. Controlling this motion via chemical or physical stimuli has resulted in the development of many stimuli-responsive interlocked systems with applications in wide range of field such as switches, molecular machinery and sensing. The latter is of particular interest as the mechanical bond within a catenane or rotaxane molecule creates a well-defined three-dimensional environment that can be readily functionalised to accommodate a variety of guest molecules. This thesis presents an investigation into the design and synthesis of novel functional rotaxane receptors and their application in the sensing of metal ions, anions and small chiral molecules.The introductory chapter presents the active template approach to interlocked molecules. It highlights its key advantages and outline recent advances that have been made using this methodology. The following three chapters focus on the study of rotaxane receptors synthesised using this approach. Chapter two reports the synthesis of a sulfur-functionalised rotaxane and the investigation of its selective response for Zn2+ ion over other transition metal cations. Chapter three on the other hand focuses on a urea-based rotaxane that binds ion-pairs. This section will introduce preliminary results obtained with a simple model rotaxane before presenting its evolution into a stimuli-responsive receptor. The binding behaviour of both the rotaxane and related non-interlocked axle will be investigated to demonstrate the impact of the mechanical bond on the properties of the receptor. In the fourth chapter, the project was expanded toward chirality and more specifically enantioselective sensing. The development of a novel synthetic route to access functionalised mechanically planar chiral rotaxanes will be presented and it will conclude on preliminary binding studies of simple chiral anionic guest that shows enantioselectivity
Data set in support of AT-CuAAC synthesis of mechanically interlocked oligonucleotides
No full textDataset supports: Acevedo-Jake, A., Ball, A. T., Galli, M., Kukwikila, N. M., Denis, M. AS., Singleton, D., Tavassoli, A., & Goldup, S. (2020). AT-CuAAC synthesis of mechanically interlocked oligonucleotides. Journal of the American Chemical Society, 142(13), 5985-5990. https://doi.org/10.1021/jacs.0c01670</span
Campodea (Campodea) kervillei Denis 1932
No full textCampodea (Campodea) kervillei Denis, 1932 Campodea (Campodea) kervillei Denis, 1932a: 75, figs 1–10. Diagnosis (Denis 1932a; Condé & Mathieu 1957; Bareth 2006) Body length 4.0–5.0 mm; epicuticle with thin microdenticles; short clothing setae with a few small apical barbs; antennae 19–29 antennomeres; sensillum of third antennomere in dorsal position; middle sized, poorly barbed, robust notal macrosetae; long, robust and barbed notal marginal setae; 1–0 trochanteral sensillum; 1+1 la on V urotergite, 1+1 la, 1+1 lp on VI–VII urotergites, 1+1 mp, 3+3 lp on VIII urotergite and 1+1 mp, 5+5 lp on IX abdominal segment; male with two separated areas of glandular g 1 -setae; cerci with 7–9 articles covered in long macrosetae with distal barbs but swollen latero-interior macrosetae and a few clothing setae; spermatozoid fascicle 50–55 μm diameter and 15–20 μm thick, spiral filament 300–400 μm long in 2–3 whorls and 3–4 μm diameter with one sharp extreme. Habitat and distribution Soil-dwelling species sometimes found in the MSS (Bareth 1983) or in caves (Denis 1932a; Condé & Mathieu 1957) but without exhibiting cave-adaptated traits. It is abundant around the Pyrenees and neigbouring areas, except its eastern border (Denis 1932b; Condé 1947c; Condé & Mathieu 1957; Sendra & Moreno 2004).Published as part of Sendra, Alberto & Reboleira, Ana Sofia P. S., 2020, Euro-Mediterranean fauna of Campodeinae (Campodeidae, Diplura), pp. 1-130 in European Journal of Taxonomy 728 on page 40, DOI: 10.5852/ejt.2020.728.1181, http://zenodo.org/record/431688
Pseudosinella sollaudi Denis 1924
No full textPseudosinella sollaudi Denis, 1924 * Pseudosinella sollaudi Denis, 1924b: 198. DISTRIBUTION. — Doubs. Grottedes Faux-Monnayeurs, gouffregrottedela Beaumedu Montà Reugney (Denis 1924b, c). — Grotte de Chauveroche (Gisin 1960b). — Grottesde Gonsans à Gonsans près de Roulans, des Cavottes à Montrond près de Quingey, des Faux-Monnayeurs à Mouthier-Hautepierre, du Baume du Mont à Reugney près d’Amancey, des Orcières à Montivernace près de Baume-les-Dames, dela Source Bergeretà Arcierprèsde Besançonnord et de Grange Mathieu à Chenecey (Gisin & Gama 1970a; Gama 1976). Drôme. Grottesdes Déramats à Saint-Martin-en-Vercors, de Barmechenelleà Saint-Julien-en-Vercors etde Ferrières à La Chapelleen-Vercors (Ginet 1961). Isère. Grotte de Pré-l’Étang à Presles, glacière de Corrençon (Ginet 1961). TAXONOMIE. — Denis 1924c (redescription); Gisin & Gama 1970a (redescription); Gama 1976 (redescription).Published as part of Thibaud, Jean-Marc, 2017, Catalogue des collemboles de France, pp. 297-436 in Zoosystema 39 (3) on page 392, DOI: 10.5252/z2017n3a1, http://zenodo.org/record/549627
Chelating rotaxane ligands as fluorescent sensors for metal ion
No full textAlthough metal‐ion‐binding interlocked molecules have been under intense investigation for over three decades, their application as scaffolds for the development of sensors for metal ions remains underexplored. In this work, we demonstrate the potential of simple rotaxanes as metal‐ion‐responsive ligand scaffolds through the development of a proof‐of‐concept selective sensor for Zn2+
Campodea (Dicampa) catalana Denis 1930
No full textCampodea (Dicampa) catalana Denis, 1930 Figs 1–4, 19–22 Campodea (Dicampa) catalana Denis, 1930: 28, figs 7–13. Diagnosis (Denis 1930; Condé & Mathieu 1957; Sendra & Jiménez 1983; Sendra & Moreno 2006) Body length 2.5–4.0 mm; epicuticle with microdenticles; short, smooth clothing setae; antennae with 18–26 antennomeres, with up to 31 in populations inhabiting shallow subsurface habitats, such as the MSS (Sendra et al. 2017a); sensillum of third antennomere in dorsal position, smaller and in ventral position in several populations in the northeast of the Iberian Peninsula; cupuliform organ with four simple olfactory chemoreceptors but increasing in number in specimens from MSS habitats; short ma and la notal macrosetae with a few barbs and long lp notal macrosetae with barbs along distal half; marginal setae with long apical barbs; 3+3 lp macrosetae on VIII urotergite, 5+5 lp on IX abdominal segment; cerci shorter than body and covered in long macrosetae with barbs along distal half to twothirds and a few shorter, smooth setae, but in proximal articles with latero-interior macrosetae ending in sharp shape to slightly swollen. Taxonomic notes The studied material (Supplementary file 2) has allowed to photograph some structures under SEM (Figs 2–4, 19–22). Habitat and distribution Soil-dwelling species inhabiting all layers of the soil, and the MSS on scree slopes (Sendra et al. 2017a), from the sea level to the highest mountains of the Iberian Peninsula under Mediterranean climate (Denis 1930; Condé & Mathieu 1957; Sendra & Jiménez 1983; Sendra & Moreno 2006).Published as part of Sendra, Alberto & Reboleira, Ana Sofia P. S., 2020, Euro-Mediterranean fauna of Campodeinae (Campodeidae, Diplura), pp. 1-130 in European Journal of Taxonomy 728 on page 69, DOI: 10.5852/ejt.2020.728.1181, http://zenodo.org/record/431688
Utilisation des propriétés des anaphores dans la définition des relations lexicales
No full textSome lexical relations (such as hyperonymy, synonymy, meronymy, polysemy and predicate/argument relation) can be defined by using, among other criteria, discursive relations. Different types of anaphora are taken into account.Le Pesant Denis. Utilisation des propriétés des anaphores dans la définition des relations lexicales. In: Langages, 32ᵉ année, n°131, 1998. Les classes d'objets, sous la direction de Denis Le Pesant et Michel Mathieu-Colas. pp. 115-124
AT-CuAAC synthesis of mechanically interlocked oligonucleotides
No full textWe present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties
Pensar las escalas para pensar las luchas: Autor: Mathieu UHEL
No full textA través de un título sugerente, “pensar las escalas para pensar las luchas”, Mathieu Uhel entreteje la construcción teórico-crítica del concepto escala, generada por la geografía radical anglosajona de finales del siglo XX, con la necesidad/utilidad práctica de la escala para concienciar las luchas sociales. El artículo cumple un doble propósito: por un lado, delinear los elementos de lectura sobre el concepto escala; y, con ello, promover la atención de esta problemática en las luchas contemporáneas. En un primer apartado, Uhel ubica las discusiones académicas en torno a la escala, como herramienta metodológica útil para comprender la complejidad de las sociedades capitalistas; en el segundo apartado, el autor avanza la exposición en torno al contexto de la dimensión escalar del imperialismo capitalista; finalmente, el autor se centra en el rol de la actividad política a escala nacional en la tensa relación entre las imposiciones del capital y la lucha social.Por meio de um título sugestivo, “pensando escalas para pensar lutas”, Mathieu Uhel entrelaça a construção teórico-crítica do conceito de escala, gerado pela geografia radical anglo-saxônica do final do século XX, com a necessidade / utilidade prática escala para aumentar a consciência das lutas sociais. O artigo tem um duplo propósito: por um lado, delinear os elementos de leitura sobre o conceito de escala; e, com isso, promover atenção a esse problema nas lutas contemporâneas. Na primeira seção, Uhel localiza as discussões acadêmicas em torno da escala, como uma ferramenta metodológica útil para compreender a complexidade das sociedades capitalistas; na segunda seção, o autor avança a exposição em torno do contexto da dimensão escalar do imperialismo capitalista; por fim, o autor enfoca o papel da atividade política em escala nacional na tensa relação entre as imposições do capital e a luta social.Mathieu Uhel\u27s suggestive title, “Thinking about scales to think about struggles”, he interweaves the theoretical-critical construction of concept scale, generated by radical Anglo-Saxon geography in the late 20th century, with it´s practical utility to social struggles. The article serves two purposes: on the one hand, Uhel locates academic discussion around scale; and, with this, he promotes attention to this problem in contemporary struggles. In the first section, Uhel locates academic discussions around scale, as a useful methodological tool to understand the complexity of capitalist societies; in the second section, the author advances the argument around the context of the scalar dimension of capitalist imperialism; finally, the author focuses on the role of political activity on a national scale in the tense relationship between the impositions of capital and the social movement
Mathieu Ichou, Les Enfants d’immigrés à l’école
No full textIt is common to hear in the fields of educational and immigration sociology that on average, the children of immigrants do not perform as well in school as children of native-born parents. Mathieu Ichou offers an innovative sociological analysis on a topic that is heavily exploited by political and media discourse, and subject to much scientific controversy. The author takes distance from the homogenized vision of a “second generation” of students who have totally failed academically, and rep..
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