1,720,984 research outputs found
Natural history of patients with subcentimeter pulmonary nodules undergoing hepatic resection for metastatic colorectal cancer.
No full textBACKGROUND: CT imaging frequently detects subcentimeter pulmonary nodules (SPN) in patients undergoing
resection of colorectal cancer liver metastases. Their clinical significance is unknown.
STUDY DESIGN: Patients were identified who underwent hepatic resection for colorectal cancer liver metastases
between October 2004 and March 2006. The presence and imaging features of preoperative
SPN were analyzed for their association with progression-free survival (PFS), disease-specific
survival (DSS), and SPN progression.
RESULTS: One hundred sixty patients underwent liver resection and 68 (43%) had SPN identified preoperatively.
Median number of nodules was 1 (75th percentile: 2 nodules) and median size of
the largest was 3mm(25th to 75th percentile: 2 to 5 mm). SPN were unilateral in 77%, calcified
in 19%, solid in 92%, and smooth in contour in 95% of patients. At median follow-up of 31
months for survivors, SPN were proven to be metastatic disease in 35% of patients (24 of 68),
either by radiographic increase in size or number (n 12) or histologic confirmation after
resection (n 12).Median PFS for the 160 patients was 16 months and 3-year DSS was 78%.
There was a trend toward shorter median PFS in patients with preoperative SPN compared with
patients with no SPN (12 versus 20 months; p0.242). There was no difference in 3-year DSS
(70% versus 83%; p 0.46). SPN progression after hepatic resection did not substantially
affect 3-year DSS. Calcified nodules were less likely to progress compared with noncalcified
nodules (8% versus 42%; p 0.03).
CONCLUSION: SPN are common among patients undergoing resection of colorectal cancer liver metastases and
approximately one-third of these will prove to be metastatic disease. Presence of limited preoperative
SPN might be associated with shorter PFS after hepatectomy, but does not substantially
impact 3-year DSS, and should not necessarily preclude resection of hepatic metastase
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Upper gastrointestinal bleeding and a unique computed tomography scan
No full text[No abstract available]DeMatteo RP, 2000, ANN SURG, V231, P51, DOI 10.1097-00000658-200001000-00008; Kindblom LG, 1998, AM J PATHOL, V152, P1259; Shojaku H, 1997, Radiat Med, V15, P189; Verweij J, 2004, LANCET, V364, P1127, DOI 10.1016-S0140-6736(04)17098-00
Vascular inflow control during hemi-hepatectomy: a comparison between intrahepatic pedicle ligation and extrahepatic vascular ligation.
No full textBackground
Intrahepatic pedicle ligation (IPL) is an alternative to extrahepatic portal dissection (EPD). Although IPL has been well described, concern has arisen over a possible association with increased complication rates.
Methods
Patients who underwent hemi-hepatectomy during January 1995 to December 2010 were reviewed and the inflow control technique (IPL versus EPD) documented. Patient, tumour, treatment and outcome variables were compared.
Results
A total of 798 patients underwent hemi-hepatectomy, 568 (71.2%) of the right and 230 (28.8%) of the left liver. In univariate analysis, factors associated with the choice of IPL included surgeon, right hepatectomy, preoperative portal vein embolization, diagnosis of colorectal cancer liver metastasis, and smaller tumour size (P < 0.011). In multivariate analysis, right hepatectomy [versus left: hazard ratio (HR) 3.878, 95% confidence interval (CI) 1.15–13.14; P = 0.029] and smaller tumour size (median of 4.5 cm versus 5.5 cm: HR 0.72, 95% CI 0.59–0.88; P = 0.002) were associated with IPL. Pringle manoeuvre time was longer in IPL procedures (40 min versus 29 min; P < 0.001). Complication rates (49.8% in IPL versus 48.4% in EPD; P = 0.706) were similar in both groups, as was the severity of complications; 17.6% of EPD and 22.3% of IPL patients experienced complications of grade ≥3 (P = 0.225).
Conclusions
Patients with small tumours undergoing right hepatectomy were more likely to undergo IPL. In selected patients, IPL was not associated with an increased complication rate and thus it should be considered a safe approach
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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