170,062 research outputs found
J.-M. Apellaniz , F.-C. Gomez La forma del arte paleolitico y la estadistica
No full textDelporte Henri. J.-M. Apellaniz , F.-C. Gomez La forma del arte paleolitico y la estadistica. In: Bulletin de la Société préhistorique française, tome 96, n°4, 1999. pp. 626-627
Involvement of aquaglyceroporins in energy metabolism in health and disease
No full textAquaglyceroporins are a group of the aquaporin (AQP) family of transmembrane water channels. While AQPs facilitate the passage of water, small solutes, and gases across biological membranes, aquaglyceroporins allow passage of water, glycerol, urea and some other solutes. Thanks to their glycerol permeability, aquaglyceroporins are involved in energy homeostasis. This review provides an overview of what is currently known concerning the functional implication and control of aquaglyceroporins in tissues involved in energy metabolism, i.e. liver, adipose tissue and endocrine pancreas. The expression, role and (dys)regulation of aquaglyceroporins in disorders affecting energy metabolism, and the potential relevance of aquaglyceroporins as drug targets to treat the alterations of the energy balance is also addressed
J.-M. Chauvet., E. Brunel-des-Champs et C. Hillaire , avec une postface de J. Clottes La grotte Chauvet à Vallon-Pont-d'Arc
No full textDelporte Henri. J.-M. Chauvet., E. Brunel-des-Champs et C. Hillaire , avec une postface de J. Clottes La grotte Chauvet à Vallon-Pont-d'Arc. In: Bulletin de la Société préhistorique française, tome 92, n°3, 1995. p. 279
C. Delporte, Les journalistes en France, 1880-1950
No full textMarchetti Dominique. C. Delporte, Les journalistes en France, 1880-1950. In: Politix, vol. 12, n°47, Troisième trimestre 1999. Changer de régime, sous la direction de Annie Collovald et Brigitte Gaïti. pp. 167-171
Mlle Delporte. — Les altérations du caractère chez l'enfant . — L. Boyer, Paris
No full textRibéry C. Mlle Delporte. — Les altérations du caractère chez l'enfant . — L. Boyer, Paris. In: Revue internationale de l'enseignement, tome 44, Juillet-Décembre 1902. pp. 464-465
Hepatobiliary, salivary glands and pancreas aquaporins in health and disease
No full textAquaporins (AQPs) are channel proteins largely present in mammals where they facilitate the permeation of water and a variety of substrates across cellular membranes. AQPs exert pleiotropic roles in both health and disease. This chapter addresses the most recent acquisitions in terms of expression and regulation, as well as physiological and pathophysiological rolesof AQPs in the hepatobiliary tract, salivary glands and pancreas. A number of AQPs are found in liver, bile ducts and gallbladder where they are playing roles in bile formation, secretion and reabsorption. Liver AQPs are also implicated in energy homeostasis by acting in hepatic gluconeogenesis and fat metabolism, and in important processes such as ammonia detoxification and mitochondrial release of hydrogen peroxide. Hepatobiliary AQPs are involved in clinical disorders including cholestasis, gallstone formation, insulin resistance, fatty liver disease, hepatic cirrhosis and hepatocarcinoma. Salivary and exocrine pancreas AQPs exert main roles in fluid secretion and contribute to the pathogenesis of xerostomia and pancreatic insufficiencies. Endocrine pancreas AQPs are suggested to be key regulators of intra-islet glycerol content as well as insulin production and secretion, and to contribute to the pathogenesis of diabetes. This body of knowledge represents the mainstay of present and future research in a rapidly expanding field
Aquaglyceroporins: drug targets for metabolic diseases?
No full textAquaporins (AQPs) are a family of transmembrane channel proteins facilitating the transport of water, small solutes, and gasses across biological membranes. AQPs are expressed in all tissues and ensure multiple roles under normal and pathophysiological conditions. Aquaglyceroporins are a subfamily of AQPs permeable to glycerol in addition to water and participate thereby to energy metabolism. This review focalizes on the present knowledge of the expression, regulation and physiological roles of AQPs in adipose tissue, liver and endocrine pancreas, that are involved in energy metabolism. In addition, the review aims at summarizing the involvement of AQPs in metabolic disorders, such as obesity, diabetes and liver diseases. Finally, challenges and recent advances related to pharmacological modulation of AQPs expression and function to control and treat metabolic diseases are discussed.SCOPUS: re.jinfo:eu-repo/semantics/publishe
Médias et transformation des imaginaires politiques
No full textIl presente capitolo analizza, in chiave comparata (Stati Uniti, Regno Unito, Francia, Germania e Italia) la mediatizzazione del dibattito politico e dei processi elettorali tra gli anni Cinquanta e gli anni Novanta del XX secolo. In particolare l'analisi si sofferma sulle trasformazioni prodotte dal mezzo televisivo sul discorso pubblico, sulle strategie elettorali dei candidati e sulla progressiva personalizzazione della sfera politica
Pouvoirs et médias
No full textIl presente capitolo analizza il tema dell'indipendenza del sistema mediatico rispetto al potere politico ed economico, in chiave comparata (vengono analizzati i casi francese, statunitense, britannico, tedesco e italiano
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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