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    Agostino Gemelli

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    Epistemological models in psychoacoustics: a historical overview

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    Since Fechner set the basis for psychophysics, psychology of sound and musical perception started its course as a scientific discipline. During less than two centuries of history, anyway, it passed through many different epistemological paradigms, influenced by the changes occurred into the historical and philosophical panorama. Starting from Fechner's 1860 volume Elemente der Psychophysik, we explore these paradigm shifts, tracking some of the principal steps made by psychology of sound and music in its attempts to offer a model for discovering and explaining the scientific phenomena and laws underlying acoustic sensations and perception, “in tune” with the different theoretical frames of the most influent psychological theories of the XIXth and XXth century

    Dalla riforma della psichiatria alla neuroetica tra scienza, medicina e società. Attualità di alcuni aspetti del pensiero di Giovanni Berlinguer

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    : Il pensiero di Giovanni Berlinguer è stato uno tra i più importanti contributi al movimento italiano sulla psichiatria degli anni Sessanta e Settanta del XX secolo, foriero di una critica profonda e di riflessioni cruciali per comprendere le istanze di cambiamento che in quegli anni attraversavano la medicina in generale e la psichiatria in particolare. Al fine di recuperarle e attualizzarle, sono discusse la teoria e la praxis di Berlinguer sui rapporti tra individuo, società e salute mentale, collegandole criticamente ad alcune aporie emerse nel dibattito neuroetico

    Using the Data Fusion tecnique for producing tematic maps.

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    The University of Salerno (Italy) has recently been equipped with a pair of aerials that are able to receive data transmitted from various satellite platforms such as the NOAA and the Terra-1 and Aqua-1 EOS. These satellites are fitted with sensors that pick up information regarding soil and cloud temperature, the humidity level of the atmosphere, the presence of extraneous water, the presence of certain substances such as chlorophyll, the surface colour of the ocean and the presence of plankton with a spatial resolution that at its greatest reaches 250 m. Great use is therefore made of a vast amount of data that concerns our geographical area which allows for a fairly approximate assessment of the state of health (desertification, deforestation, abundance of surface water) and the potential risks (landslides, fires, plant and crop infections or diseases) to which the territory is prone. Nevertheless, the data is supplied with differing precision to the ground and with different pixel dimensions, therefore it is not possible to generate, taking as a starting point the data alone, (thematic map) which, besides furnishing qualitative information, also supplies correct and precise metric information. By using the Data Fusion technique it is possible to project the data supplied by various sensors onto a higher resolution image in order to obtain a representation that allows for a synthesis of all available information

    Comparative analysis of three methods in anti-dsDNA antibodies detection: implications for Systemic Lupus Erythematosus diagnosis

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    The evaluation of anti-dsDNA antibodies represents one of the essential diagnostic and prognostic marker features in patients affected by Systemic Lupus Erythematosus (SLE). In this study, we have compared immunoblotting (IB) with Crithidia luciliae indirect immunofluorescence test (CLIFT) and chemiluminescent immunoassay (CLIA) in 91 patients referred to our hospital for anti-dsDNA antibodies detection. The concordance and correlation measured by Cohen's kappa and Spearman's coefficient respectively was significant between CLIFT and CLIA (0.70; 0,7404, P <.0001) and among CLIA and IB (0.79; 0,5377, P < 0,0001) and lower between CLIFT and IB (0.55; 0,4373, P <0,0001). Among the 46 IB-positive samples, 14 were positive for either CLIA or CLIFT. It is noteworthy that 11 out of these 14 samples had the final diagnosis of SLE. Thirteen out of fourteen samples were also positive for anti-nucleosome antibodies as measured concomitantly in immunoblotting. While our observations are based on a limited number of samples and will have to be confirmed in a bigger cohort, they underline the contribution of immunoblotting as an additional assay in defining the anti-dsDNA antibody profile in association with other well-established methods such as CLIA and CLIFT
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