612 research outputs found

    [Superseded] Built environment and transit use empirical research database

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    <div>This dataset has been replaced by the Built Environment and transit Use meta-database. Please visit </div><div>https://doi.org/https://doi.org/10.26180/5d921ac827289</div><div><br></div><div><br></div><div>Aston, L., Currie, G., Kamruzzaman, M., Delbosc, A., & Teller, D. (2019). BE-TU: Built Environment and Transit Use Meta-database (Version 1) [Meta-database]. <br></div><div><br></div><div>Notes</div><div>1 - Aston, Laura; Currie, Graham; Delbosc, Alexa; O'Hare, Tyler; Kamruzzaman, MD; Teller, David (2019): Empirical built environment and transit use literature since 2000: Comprehensive literature review protocol and results. figshare. Dataset. Available on figshare at <a href="https://doi.org/10.26180/5c3fd9990600c">https://doi.org/10.26180/5c3fd9990600c</a></div><div><br></div><div></div&gt

    [Superseded] Built environment and transit use meta-analysis database

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    This database is no longer maintained. For the up to date supporting data associated with publication listed below, please visit: <div>https://github.com/Laura-k-a/BE-TU-Meta-analysis.<div><br><div><div><div>Aston, L., Currie, G., Delbosc, A., Kamruzzaman, M., & Teller, D. (2020). Exploring built environment impacts on transit use - An updated meta-analysis. Transport Reviews. https://doi.org/10.1080/01441647.2020.1806941 <br></div><div><br></div><div><br></div><div><br></div><div>Superseded database description<br><div><br></div><div>This database contains a subset of another online database compiled by the authors (1). The purpose of this database is to provide traceability over the source data and methodology used to estimate elasticities for the relationship between indicators of the built environment and transit use.<div><br></div><div>The 505 elasticity estimates contained in this workbook are sourced directly or derived using information available in 76 prior studies.<div><div><div><br></div><div><b>Main content</b></div><div><b>Overview</b> - Complete index of database content, include calculation steps</div><div><b>Metadata - </b>Index of column headers describing attributes and corresponding levels in 'Database'</div><div><b>Database</b> - Database information for 505 data points from 76 studies. Study attributes and quantitative information relevant to screening and calculation steps is included. </div><div><b><br></b></div><div><b>Calculation steps</b></div><div><b>10_ Mean elasticities</b> - Calculation of mean elasticities based on average of the weighted elasticities for data points of each indicator</div><div><b>11_results_summary - </b>Summary of mean elasticity and significance level for each indicator</div><div><b>Sample_only</b> Static table containing data for the 226 data points in the final sample</div><div><br></div><div>Notes</div><div>1 - Aston, Laura; Currie, Graham; Delbosc, Alexa; Kamruzzaman, MD; O'Hare, Tyler; Teller, David (2019): Built environment and transit use empirical research database. figshare. Dataset. Available on figshare: https://doi.org/10.26180/5c3fe01b7fd7e</div></div></div></div></div></div></div></div></div></div&gt

    The construction of Karen Karnak: The multi-author-function

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    This thesis is situated within the comparatively recent developments of Web 2.0 and the emergence of interactive WikiMedia, and explores the mode of authorship within a Read/Write culture compared to that of a Read/Only tradition. The hypothesis of this study is that the role of the audience has become merged with the author, and as such, represents new functions and attributes, distinct from a more conventional concept of authorship, in which the roles of audience and author are more separate. Read/Write and participatory culture, as defined by this study, is focused on collaboration, and includes the influences of D.I.Y. culture, Open-Source practices and the production of text by multiple authors. Multi-authorship presents a re-thinking of several concepts which support the notion of the individual author, since the focus of multi-authorship is not on attribution and ownership of a finished text, but on the continued malleability of a text. Modes of multi-authorship, demonstrated in the use of the pseudonyms Alan Smithee and Karen Eliot, represent declarative authors whose names signify multiple origins, whilst concurrently indicating a distinct body of work. The function of these names form an important context to this study, since primary research involves the construction of an experimental mode of multi-authorship utilising WikiMedia technology and the interaction of thirty nine participants, who are invited to create a body of work under the collective pseudonym Karen Karnak. The data generated by this experiment is analysed using aspects of Michel Foucault's author-function to identify and determine power structures inherent in the WikiMedia context. The interplay of power structures, including concepts such as identity, ownership and the body of work, affect the resulting mode of authorship and contribute to the construction of Karen Karnak, suggesting further areas of research into the emerging multi-author

    The Magazine Women Believed in: "Marriage Advice" 1950-1955

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    In the United States society, the 1950s is seen as a time of great conservatism where both men and women were placed into specific gender roles that dictated much of how they lived their lives. One institution that verified these gender roles and stereotypes to be true was women's magazines. These magazines contained sections such as fashion segments, helpful cooking guidelines, advertisements, and advice columns that seemed to target middle class, white, suburban married housewives. One advice column that seemed to particularly focus on the idea of a happy housewife and married life was the column Making Marriage Work, which appeared in the magazine Ladies Home Journal during this 1950s time period. The author of this column, Clifford R. Adams, idealized the 1950s perfect housewife existence and through his advice he encouraged women to strive for this lifestyle, while there were other sources demonstrating that this perceived notion of the perfect housewife did not exist during the 1950s time period

    Alexa Discussion Board Skill

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    abstract: A common challenge faced by students is that they often have questions about course material that they cannot ask during lecture time. There are many ways for students to have these questions answered, such as office hours and online discussion boards. However, office hours may be at inconvenient times or locations, and online discussion boards are difficult to navigate and may be inactive. The purpose of this project was to create an Alexa skill that allows users to ask their Alexa-equipped device a question concerning their course material and to receive an answer retrieved from discussion board data. User questions are mapped to discussion board posts by use of the cosine similarity algorithm. In this algorithm, posts from the discussion board and the user’s question are converted into mathematical vectors, with each term in the vector corresponding to a word. The values of these terms are computed based on the word’s frequency within the vector’s corresponding document, the frequency of that word within all the documents, and the length of the document. After the question and candidate posts are converted into vectors, the algorithm determines the post most similar to the user’s question by computing the angle between the vectors. With the most similar discussion board post determined, the user receives the replies to the post, if any, as their answer. Users are able to indicate to their Alexa device whether they were satisfied by the answer, and if they were unsatisfied then they are given the opportunity to either rephrase their question or to have the question sent to a database of unanswered questions. The professor can view and answer the questions in this database on a website hosted by use of Amazon’s Simple Storage Service. The Alexa skill does well at answering questions that have already been asked in the discussion board. However, the skill depends heavily on the user’s word choice. Two questions that are semantically identical but different in phrasing are often given different answers. This is because the cosine algorithm measures similarity on the basis of word overlap, not semantic meaning, and thus the application never truly “understands” what type of answer the user desires. Improving the performance of this Alexa skill will require a more advanced question answering algorithm, but the limitations of Amazon Web Services as a development platform make implementing such an algorithm difficult. Nevertheless, this project has created the basis of a question answering Alexa skill by demonstrating a feasible way that the resources offered by Amazon can be utilized in order to build such an application

    Author Correction: Hippocampal oxytocin receptors are necessary for discrimination of social stimuli

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    The original version of this Article contained an error in the spelling of the author Alexa H. Veenema, which was incorrectly given as Alexa Veenema. This has now been corrected in both the PDF and HTML versions of the Article.</jats:p

    Built environment and transit use meta-analysis database

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    This database contains a subset of another online database compiled by the authors (1). The purpose of this database is to provide traceability over the source data and methodology used to estimate elasticities for the relationship between indicators of the built environment and transit use.The 505 elasticity estimates contained in this workbook are sourced directly or derived using information available in 76 prior studies.Main contentOverview - Complete index of database content, include calculation stepsMetadata - Index of column headers describing attributes and corresponding levels in 'Database'Database - Database information for 505 data points from 76 studies. Study attributes and quantitative information relevant to screening and calculation steps is included. Calculation steps10_ Mean elasticities - Calculation of mean elasticities based on average of the weighted elasticities for data points of each indicator11_results_summary - Summary of mean elasticity and significance level for each indicatorSample_only Static table containing data for the 226 data points in the final sampleNotes1 - Aston, Laura; Currie, Graham; Delbosc, Alexa; Kamruzzaman, MD; O'Hare, Tyler; Teller, David (2019): Built environment and transit use empirical research database. figshare. Dataset. Available on figshare: https://doi.org/10.26180/5c3fe01b7fd7e</div

    Melbourne built environment and transit use empirical dataset

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    &lt;div&gt;A beta version of the Ridership Performance tool for Greater Melbourne has been added to this collection of data in version 4. &lt;br&gt;&lt;/div&gt;&lt;div&gt;&lt;br&gt;&lt;/div&gt;&lt;div&gt;Please note: changes have bene made to this database since publication of Aston, L., Currie, G., Kamruzzaman, M., Delbosc, A., Fournier, N., & Teller, D. (2020). Addressing transit mode location bias in built environment-transit mode use research. Journal of Transport Geography, 87(July 2020). https://doi.org/https://doi.org/10.1016/j.jtrangeo.2020.102786 &lt;/div&gt;&lt;div&gt;The current version (3) should be used for all future planning and forecasting. &lt;/div&gt;&lt;div&gt;&lt;br&gt;&lt;/div&gt;&lt;div&gt;Please refer to version 2 of this dataset if you would like to test the assumptions and findings of the study mentioned above.&lt;/div&gt;&lt;div&gt;&lt;br&gt;&lt;/div&gt;&lt;div&gt;&lt;b&gt;Description&lt;/b&gt;&lt;/div&gt;The main database file presented here (BETU.Melbourne.Database.v3_20201006) contains indicators of the station-are built environment and sociodemographic characteristics at Melbourne's train, tram and bus stops.&lt;div&gt;&lt;br&gt;&lt;/div&gt;&lt;div&gt;The database is practice-ready, constituting a valuable input to understanding built environment impacts on transit ridership.&lt;/div&gt;&lt;div&gt;&lt;br&gt;&lt;/div&gt;&lt;div&gt;Supporting files contained in this dataset include:&lt;/div&gt;&lt;div&gt;- Stop-level data, mapped to 'facilities' (groups of nearby stops)&lt;/div&gt;&lt;div&gt;- Polygon-level data&lt;br&gt;&lt;/div&gt;&lt;div&gt;- Data protocol describing the inputs to the database&lt;br&gt;&lt;/div&gt

    BE-TU: Built Environment and Transit Use Meta-database

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    The BE-TU meta-database provides a comprehensive repository of empirical built environment and transit use studies. Its purpose is to increase the visibility of relevant empirical built environment and transit use research, making future knowledge development in the field easier and more robust. Suggestions, feedback and use cases:This meta-database is a living repository of research. Use this link to submit a study for inclusion in the meta-database, provide feedback or share an example of application of the database.http://tiny.cc/BE-TURedirection:Quantitative information pertaining to manuscript: Aston, L., Currie, G., Delbosc, A., Kamruzzaman, M and Teller, D. 2020, Study design impacts on built environment and transit use research, Journal of Transport Geography (82), https://doi.org/10.1016/j.jtrangeo.2019.102625is stored on GitHub: Aston, L. 2020, Laura-k-a/BE-TU-Study-Design-Impacts, GitHub, https://github.com/Laura-k-a/BE-TU-Study-Design-Impacts. ScopeThe datum of interest is the relationship between a transit use (dependent or outcome variable) and the built environment (independent or predictor variable). The database contains qualitative information about study design as well as high-level results, coded in terms of the direction and significance of each BE-TU relationship. The scope of coded data includes:- Prior study citation information- Descriptive estimates of relationships between BE and TU- Dependent (TU) variables- Independent (BE) variables- Sample attributes- Study design- Model specificationA comprehensive identification, eligibility, extraction and coding framework was followed to construct the database (1).Database Contents1. BE-TU_Meta-database: Study design and descriptive BE-TU relationships from priors, coded at data-point level. Contains 1,662 data points from 146 priors identified from original search. 2. Priors_Reference_List: Citation information for priors. Contains 186 priors: 146 from original search (7 Dec 2017) and 40 from search update (30 Oct 2019) (3). 3. BE-TU_Metadata_study design: Index of column headers corresponding to attributes extracted from priors and corresponding levels. 4. BE-TU_Metadata_BE: Index of built environment variables and indicators coded in database. Attribution Evidence obtained directly from the database should include reference to the database as well as the prior studies from which the findings or descriptive information is taken. Citation information for all priors is included in the database, and identifiable using numeric study design IDs. BE-TU Meta-database CitationAston, L., Currie, G., Delbosc, A., Kamruzzaman, M., & Teller, D. (2019) BE-TU (Built environment and transit use) Meta- Database, figshare, https://doi.org/10.26180/5d921ac827289Update Log:Version 2 (current): Published 10 January 2020Version 1: Published 6 November 2019Notes 1 - Aston, Laura; Currie, Graham; Delbosc, Alexa; O'Hare, Tyler; Kamruzzaman, MD; Teller, David (2019): Empirical built environment and transit use literature since 2000: Comprehensive literature review protocol and results. figshare. Dataset. https://doi.org/10.26180/5c3fd9990600c 2 – The updated meta-database search protocol and guidelines for use are included in a paper that is currently under review. The paper will be linked to this overview once reviewed.3 - 40 studies have been identified for inclusion in the database following a pilot of the updated search protocol on 30 October 2019. These studies are included in 2. Priors_Reference_List. Descriptive information for data points will be added to meta-database version 3.</p

    Interchromophoric Interactions Between TMR, Alexa, and BODIPY Fluorophores

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    abstract: The fundamental photophysics of fluorescent probes must be understood when the probes are used in biological applications. The photophysics of BODIPY dyes inside polymeric micelles and rhodamine dyes covalently linked to proteins were studied. Hydrophobic boron-dipyrromethene (BODIPY) dyes were noncovalently encapsulated inside polymeric micelles. Absorbance and fluorescence measurements were employed to study the photophysics of these BODIPY dyes in the micellar environments. Amphiphilic polymers with a hydrophobic character and low Critical Micelle Concentration (CMC) protected BODIPYS from the aqueous environment. Moderate dye loading conditions did not result in ground-state dimerization, and only fluorescence lifetimes and brightnesses were affected. However, amphiphilic polymers with a hydrophilic character and high CMC did not protect the BODIPYS from the aqueous environment with concomitant ground-state dimerization and quenching of the fluorescence intensity, lifetime, and brightnesses even at low dye loading conditions. At the doubly-labeled interfaces of Escherichia coli (E. coli) DNA processivity β clamps, the interchromophric interactions of four rhodamine dyes were studied: tetramethylrhodamine (TMR), TMR C6, Alexa Fluor 488, and Alexa Fluor 546. Absorbance and fluorescence measurements were performed on doubly-labeled β clamps with singly-labeled β clamps and free dyes as controls. The absorbance measurements revealed that both TMR and TMR C6 readily formed H-dimers (static quenching) at the doubly-labeled interfaces of the β clamps. However, the TMR with a longer linker (TMR C6) also displayed a degree of dynamic quenching. For Alexa Fluor 546 and Alexa Fluor 488, there were no clear signs of dimerization in the absorbance scans. However, the fluorescence properties (fluorescence intensity, lifetime, and anisotropy) of the Alexa Fluor dyes significantly changed when three methodologies were employed to disrupt the doubly-labeled interfaces: 1) the addition of sodium dodecyl sulfate (SDS) detergent to denature the proteins, 2) the addition of clamp loader (γ complex) to open one of the two interfaces, and 3) the use of subunit exchange to decrease the number of dyes per interface. These fluorescence measurements indicated that for the Alexa Fluor dyes, other interchromophoric interactions were present such as dynamic quenching and homo-Förster Resonance Energy Transfer (homo-FRET).Dissertation/ThesisDoctoral Dissertation Chemistry 201
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