2,701 research outputs found
L' Occhio del poeta: a máquina abstrata muriliana
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Literatura.No intuito de selecionar, analisar e inter-relacionar os escritos sobre arte de Murilo Mendes, escritos em português e em italiano (poesia e prosa), este estudo configura-se como um texto em metamorfose através da filosofia deleuzo-guattariana. Cada estrato engendra substratos que se entrelaçam: os primeiros anos no Brasil, a desterritorialização do poeta, o contato com a arte e com os pintores abstratos italianos, os símbolos torcitários, o corte e a fissura. Tais elementos contribuem para o estudo da trama poética tecida pela máquina abstrata muriliana em relação ao visível e suas manifestações
Acute Infectious Diarrhea
No full textAcute infectious diarrhea (AID) is one of the most common diseases in pediatric age with relevant burden both in high and in low-income countries. Thanks to their direct action on enterocyte functions and indirect actions on the mucosal and systemic immune system and on intestinal microbiome, probiotics are an ideal intervention to treat AID in childhood. However, their efficacy is strictly related to strains and indications, and practitioners should take this information into account in clinical practice. This chapter summarizes the main mechanisms of action of probiotics in AID, with a focus on proof of efficacy supporting their use in prevention and treatment of childhood AID. The use of selected strains in appropriate doses is strongly recommended by guidelines of AID, based on compelling proofs of efficacy and safety. At present, therapy with probiotics of AID is probably the strongest indication for probiotic use in medicine. Their role in prevention of AID is however questionable in healthy population, whereas it should be considered in at-risk population. Evidence for prevention of diarrhea in day-care centers and communities is lacking, but consistent evidence supports efficacy in prevention of hospital acquired diarrhea. Finally, this chapter presents novelties on this topic, in particular the role of rotavirus immunization on probiotics effectiveness and the effect of probiotics and postbiotics on Covid-associated diarrhea. Overall: AID is the most convincing area for probiotic use in children with gastrointestinal disorders, and effective strains should be used early on after onset of symptoms
Homo poeta
No full textDalle origini preistoriche a oggi, la figura del poeta sembra assumere un ruolo centrale nelle comunità dell'Europa: l'articolo ne ricerca l'evidenza archeologica ed etnolinguistica, inferendo una sostanziale continuità tra lo sciamanesimo arcaico e le figure dei poeti tradizionali dell'Europa modern
CD49d in B-cell chronic lymphocytic leukemia: correlated expression with CD38 and prognostic relevance
No full text
Response to B-cell-depleting therapy with rituximab reverts the abnormalities of T-cell subsets in patients with idiopathic thrombocytopenic purpura
No full textRituximab, an anti-CD20 monoclonal antibody, has been used to treat autoimmune disorders such as idiopathic thrombocytopenic purpura (ITP). However, its mechanisms of action as well as the effects on cellular immunity remain poorly defined. We investigated the changes of different peripheral blood T-cell subsets, the apoptosis profile, as well as the changes of T-cell receptor (TCR) beta-variable (VB) region gene usage of CD4(+) and CD8(+) T-cell subpopulations following rituximab therapy. The study involved 30 patients with chronic ITP who received rituximab, of whom 14 achieved a durable (> 6 months) response. Compared with the control group, pretreatment abnormalities of T cells in ITP patients included an increase of the Th1/Th2 ratio and of the Tc1/Tc2 ratios (P <.001), increased expression of Fas ligand on Th1 and Th2 cells (P <.001), increased expression of Bc1-2 mRNA (P =.003) and decreased expression of Bax mRNA (P =.025) in Th cells, and expansion of oligoclonal T cells with no preferential use of any TCR VB subfamily. These abnormalities were reverted in responders at 3 and 6 months after treatment, whereas they remained unchanged in nonresponders. Our findings indicate that in patients with ITP, response to B-cell depletion induced by rituximab is associated with significant changes of the T-cell compartment
Reírse del infierno. Comentario a La concepción dionisíaca del mundo
No full textEste trabajo considera con toda seriedad la posibilidad de que el verdadero espíritu trágico que el nietzscheano reivindica consista en el humorismo, y no en la conformidad religiosa con el logos o con el destino, de un Heráclito o un Sófocles. Para ello nos vamos a centrar en un brillante texto del joven Nietzsche, pero además nos ayudaremos de alguna referencia a Schopenhauer, Dickens, Freud y Wittgenstei
L’esordio del Guarini ’Poeta per musica’: le intonazioni della raccolta "Musica nova" (1569) di Giulio Fiesco
No full textStudio sulla raccolta "Musica nova" di Giulio Fiesco, basata su liriche di Battista Guarini. Questa edizione musicale segna l'inizio delle straordinaria fortuna musicale del poeta ferrarese
Miguel Hernández en Italia: sus creaciones lingüísticas a través de las traducciones italianas
No full textHan pasado muchos años desde que el italiano Dario Puccini se dedicara al estudio y traducción de la obra hernandiana y aún así, sigue siendo el trabajo más completo que se puede encontrar en el país transalpino. Otros estudiosos como Oreste Macrí y Gabriele Morelli dedicaron también su estudio a la vida y obra del poeta alicantino, pero todo ello se llevó a cabo principalmente desde los sesenta y llegó hasta los 90. Luego van apareciendo aportaciones de hispanistas como Francisco Lobera, otros hispanistas que dedicaron su estudio en 2008 a Hernández tras un congreso en Roma como Norbert Von Prellwitz o Loretta Frattale y alguna que otra tesis de licenciatura dedicada sobre todo a la recepción del texto hernandiano. Pero queda pendiente, sin duda alguna, la recepción de esa creación hernandiana, de esos juegos de palabras, adivinanzas que si bien en la lengua de Cervantes a veces cuesta descifrar, se convierten en un total desafío en la lengua de Dante. Es así que leyendo los estudios de Puccini y sobre todo entreteniéndonos en sus traducciones y en las de Macrí, podemos entender lo complejo culto, apasionante que es enfrentarse a una obra llena de neologismos y creaciones propias del poeta.
Si ya el estudioso y lector de la obra hernandiana encuentran todo tipo de dificultades y retos en el descifrar las adivinanzas del poeta, el traductor se encuentra ante su máximo reto: poder crear de la misma manera en la lengua de llegada. Y en ello centraré mi intervención: la recepción de Hernández, ver qué fue lo que más llegó a Italia del autor, el original o la traducción y el reto que esta representa
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