4,918 research outputs found

    Structural Geology of the Cariboo Gold Mining District, East-Central British Columbia:

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    L.C. Struik.Memoir (Geological Survey of Canada) ; 421

    L.C. Sachica, Exposicion y glosa del constitucionalismo moderno

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    L.C. Sachica, Exposicion y glosa del constitucionalismo moderno. In: Revue internationale de droit comparé. Vol. 30 N°2, Avril-juin 1978. pp. 712-713

    L.c tech

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    El proyecto aborda el impacto de la tecnología en la optimización de procesos dentro de una empresa de TI, específicamente en L.C TECH. Se analiza la importancia de la automatización y digitalización de tareas para mejorar la eficiencia y reducir costos. Mediante el uso de herramientas avanzadas, se busca mejorar la calidad del servicio y aumentar la competitividad en el mercado. Además, se enfatiza la importancia de un adecuado manejo de datos y ciberseguridad para proteger la información sensible. Este estudio proporciona una visión detallada de cómo implementar tecnologías de vanguardia en una empresa de TI para lograr una operación más eficiente y seguraPregradoIngeniero(a) de sistema

    Il giudice a quo e le leggi costituzionalmente necessarie

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    Articolo pubblicato in "Rivista telematica giuridica dell'Associazione Italiana dei Costituzionalisti" - registrata presso il Tribunale di Roma - n.339 del 05.08.2010 - Direttore responsabile Valerio Onid

    Depolarization and decreased surface expression of K+ channels contribute to NSAID-inhibition of intestinal restitution

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    Non-steroidal anti-inflammatory drugs (NSAIDs) contribute to gastrointestinal ulcer formation by inhibiting epithelial cell migration and mucosal restitution; however, the drug-affected signaling pathways are poorly defined. We investigated whether NSAID inhibition of intestinal epithelial migration is associated with depletion of intracellular polyamines, depolarization of membrane potential (Em) and altered surface expression of K+ channels. Epithelial cell migration in response to the wounding of confluent IEC-6 and IEC-Cdx2 monolayers was reduced by indomethacin (100μM), phenylbutazone (100μM) and NS-398 (100μM) but not by SC-560 (1μM). NSAID-inhibition of intestinal cell migration was not associated with depletion of intracellular polyamines. Treatment of IEC-6 and IEC-Cdx2 cells with indomethacin, phenylbutazone and NS-398 induced significant depolarization of Em, whereas treatment with SC-560 had no effect on Em. The Em of IEC-Cdx2 cells was: −38.5±1.8mV under control conditions; −35.9±1.6mV after treatment with SC-560; −18.8±1.2mV after treatment with indomethacin; and −23.7±1.4mV after treatment with NS-398. Whereas SC-560 had no significant effects on the total cellular expression of Kv1.4 channel protein, indomethacin and NS-398 decreased not only the total cellular expression of Kv1.4, but also the cell surface expression of both Kv1.4 and Kv1.6 channel subunits in IEC-Cdx2. Both Kv1.4 and Kv1.6 channel proteins were immunoprecipitated by Kv1.4 antibody from IEC-Cdx2 lysates, indicating that these subunits co-assemble to form heteromeric Kv channels. These results suggest that NSAID inhibition of epithelial cell migration is independent of polyamine-depletion, and is associated with depolarization of Em and decreased surface expression of heteromeric Kv1 channels.ID: S0006295207001931; M3: Article; Accession Number: S0006295207001931; Author: L.C. Freeman (b); Author: D.F. Narvaez (a); Author: A. McCoy (a); Author: F.B. von Stein (c); Author: S. Young (b); Author: K. Silver (a); Author: S. Ganta (b); Author: D. Koch (b); Author: R. Hunter (b); Author: R.F. Gilmour (c); Author: J.D. Lillich (a, ⁎); Affiliation: Department of Clinical Sciences, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, United States; Keyword: Non-steroidal anti-inflammatory drugs; Keyword: Intestinal epithelial cells; Keyword: Membrane potential; Keyword: Potassium channels; Number of Pages: 12; Language: English;Source type: Electronic(1)http://search.ebscohost.com/login.aspx?direct=true&db=edselp&AN=S0006295207001931&site=eds-live&scope=sit

    L'esame del polso arterioso : dall'oblio alla rinascita?

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    It seems reasonable to suppose that there is some relationship between the fanciful descriptions of arterial pulse dating back to ancient times and the more sophisticated data stemming from the technological advances of recent years. The clinical evidence derived from "the flowing blood" has always been associated with diseases of the heart and vessels and indeed of apparently unrelated organs, as well as with emotional states. Centuries before the Christian era, Chinese and Indian doctors seat great store by the study of the pulse which was described in imaginative terms and considered a clue to a person's character and illnesses. This subject was just as important to Greeks and Romans: to mention just one famous name Galeno, who wrote extensively about pulses. Up to the 18th century many European Universities had chairs entitled: "De pulsibus et urines" and from this time onwards sphygmic doctrine gained an ever-growing space in the scientific literature in the attempt to establish diagnostic and prognostic connections (often rather whimsical ones) between different kinds of pulses and so-called "crises of cerebral, thoracic and abdominal organs". Between the mid 18th century and the end of the 19th century the study of pulses was mainly focused on identifying arrhythmias and valvular defects even though we still find descriptions of "alternating" and "paradoxical" pulses accompanied by somewhat ambiguous explanations. From the second half of the 20th century the possibility of measuring the pulse wave velocity and the "augmentation index" has led to remarkable advances in epidemiological studies of cardiovascular diseases. This work would like to draw the readers' attention to the relevance a simple semeiological practice such as the examination of the pulse still has in the clinical approach to a patient even in these modern times

    Commento all'articolo 81 del trattato UE

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    Si tratta di una corposa analisi dei principi fondamentali del diritto antitrust comunitario, con particolare riferimento all'art. 81, che tratta delle restrizioni della concorrenza dovute ad intese, pratiche concordate, decisioni di associazioni di impresa e organismi similari. Il commento è stato redatto attraverso una analisi giurisprudenziale e della prassi applicativa comunitarie particolarmente approfondita

    Commento agli artt. 29-35 del Reg. Ce 40/94 sul marchio comunitario

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    Commento alle norme del regolamento sul marchio comunitario 40/94 relative agli istituti della priorità e della preesistenz
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