197,624 research outputs found
Muscles growing older: inflammatory markers and sex hormones as determinants of sarcopenia and decline in physical functioning
No full textDeeg, D.J.H. [Promotor]Visser, M. [Promotor]Pluijm, S.M.F. [Copromotor
Feeling healthy versus being healthy: change and stability in older people s self-rated health
No full textDeeg, D.J.H. [Promotor]Braam, A.W. [Promotor]Huisman, M. [Copromotor
Dense array EEG (dEEG) source estimation in neocortical epilepsy
No full textRationale : Dense array EEG (dEEG) evenly covers the whole head surface with over 100 channels contributing to more accurate electrical source imaging due to the higher spatial and temporal resolution. Several studies have shown the clinical utility of dEEG in presurgical clinical evaluation of epilepsy. However validation studies measuring the accuracy of dEEG source imaging are still needed. This can be achieved through simultaneously recording both scalp dEEG with intracranial EEG (icEEG), which is considered as the true measure of cortical activity at the source. The purpose of this study is to evaluate the accuracy of 256-channel dense array EEG (dEEG) electrical source estimation for interictal spikes.Methods : Four patients with medically refractory neocortical epilepsy, all surgical candidates, underwent subdural electrode implantation to determine ictal onset and define functional areas. One patient showed a lesion on the MRI in the right parietal lobe. The patient underwent simultaneous recording of interictal spikes by both scalp 256-channelsvdEEG and icEEG. The dEEG was used to noninvasively estimate the source of the interictal spikes detected by the 256-channel dEEG array, which was then compared to the activity measured directly at the source by the icEEG.Results : From the four patients, a total of 287 interictal spikes were measured with the icEEG. 155 of the 287 spikes (54%) were visually detected by the dEEG upon examination of the 256 channel head surface array. The spike amplitudes detected by the 256-channel dEEG correlated with icEEG spike amplitudes (p < 0.01). All spikes detected in dEEG were localized to the same lobe correctly. ConclusionOur study demonstrates that 256-channel dEEG can reliably detect interictal spikes and localize them with reasonable accuracy. 256-channel dEEG may be clinically useful in the presurgical work-up for epilepsy and also reduce the need for invasive EEG evaluation
When your hearing fails you: Hearing loss determinants, psychosocial consequences, and possible interventions following screening in older adults
No full textFesten, J.M. [Promotor]Deeg, D.J.H. [Promotor]Kramer, S.E. [Copromotor
How Tough Times Become Good Times: Studies on socioeconomic inequality, resilience, and successful aging
No full textHuisman, M. [Promotor]Deeg, D.J.H. [Promotor
Equine recurrent uveitis - A spontaneous horse model of uveitis
No full textEquine recurrent uveitis (ERU) is an autoimmune disease that occurs with a high prevalence (10%) in horses. ERU represents the only reliable spontaneous model for human autoimmune uveitis. We already identified and characterized novel autoantigens (malate dehydrogenase, recoverin, CRALBP) by analyzing the autoantibody-binding pattern of horses affected by spontaneous recurrent uveitis (ERU) to the retinal proteome. CRALBP also seems to be relevant to human autoimmune uveitis. Proteomic screening of vitreous and retinal samples from ERU diseased cases in comparison to healthy controls has led to the identification of a series of differentially regulated proteins, which are functionally linked to the immune system and the maintenance of the blood-retinal barrier. Copyright (c) 2008 S. Karger AG, Basel
A risk profile for identifying community-dwelling elderly with a highrisk of recurrent falling: results of a 3-year prospective study
No full textIntroduction: The aim of the prospective study reported here was to develop a risk profile that can be used to identify community-dwelling elderly at a high risk of recurrent falling. Materials and methods: The study was designed as a 3-year prospective cohort study. A total of 1365 community-dwelling persons, aged 65 years and older, of the population-based Longitudinal Aging Study Amsterdam participated in the study. During an interview in 1995/1996, physical, cognitive, emotional and social aspects of functioning were assessed. A follow-up on the number of falls and fractures was conducted during a 3-year period using fall calendars that participants filled out weekly. Recurrent fallers were identified as those who fell at least twice within a 6-month period during the 3-year follow-up. Results: The incidence of recurrent falls at the 3-year follow-up point was 24.9% in women and 24.4% in men. Of the respondents, 5.5% reported a total of 87 fractures that resulted from a fall, including 20 hip fractures, 21 wrist fractures and seven humerus fractures. Recurrent fallers were more prone to have a fall-related fracture than those who were not defined as recurrent fallers (11.9% vs. 3.4%; OR: 3.8; 95% CI: 2.3-6.1). Backward logistic regression analysis identified the following predictors in the risk profile for recurrent falling: two or more previous falls, dizziness, functional limitations, weak grip strength, low body weight, fear of falling, the presence of dogs/cats in the household, a high educational level, drinking 18 or more alcoholic consumptions per week and two interaction terms (high educationx18 or more alcohol consumptions per week and two or more previous falls x fear of falling) (AUC=0.71). Discussion: At a cut-off point of 5 on the total risk score (range 0-30), the model predicted recurrent falling with a sensitivity of 59% and a specificity of 71%. At a cut-off point of 10, the sensitivity and specificity were 31% and 92%, respectively. A risk profile including nine predictors that can easily be assessed seems to be a useful tool for the identification of community-dwelling elderly with a high risk of recurrent falling. © International Osteoporosis Foundation and National Osteoporosis Foundation 2006
Table of Contents
No full textEditorial i
Preaching During the COVID-19 Pandemic in South Africa Marileen Steyn, Cas Wepener and Hennie Pieterse 1
Prediking ten tyde van die COVID-19-pandemie Marileen Steyn, Cas Wepener and Hennie Pieterse 21
Awakening to Judaism and Jews in Christian Preaching Ellen T. Charry 41
Light Art, Street Art, and the Art of Preaching David M. Csinos 74
Preaching in a Post-Truth Era HyeRan Kim-Cragg 88
Neuroscience and Homiletics in Dialogue Klaus A. Stange 103
Neurociência e Homilética em diálogo Klaus A. Stange 121
Homiletical Squib Alexander Deeg 14
Table of Contents
No full textEditorial i
Preaching During the COVID-19 Pandemic in South Africa Marileen Steyn, Cas Wepener and Hennie Pieterse 1
Prediking ten tyde van die COVID-19-pandemie Marileen Steyn, Cas Wepener and Hennie Pieterse 21
Awakening to Judaism and Jews in Christian Preaching Ellen T. Charry 41
Light Art, Street Art, and the Art of Preaching David M. Csinos 74
Preaching in a Post-Truth Era HyeRan Kim-Cragg 88
Neuroscience and Homiletics in Dialogue Klaus A. Stange 103
Neurociência e Homilética em diálogo Klaus A. Stange 121
Homiletical Squib Alexander Deeg 14
The Birth of the Buddha and Related Episodes as Represented in Chinese Art
No full textThe essay treats the theme of the representation of the events surrounding the birth of the Buddha and the ceremonies commemorating these episodes in India, China, Korea and Japan. It deals in particular with a specific iconology associated with the episode of the Seven Steps, which depicts the child Buddha with the right arm aloft and the left pointing to the earth in the act of proclaiming his superiority over the whole universe.
This image is unknown in the Indian cultural context and is still the object of celebrations held on the eighth day of the fourth month of the Chinese, Korean, Japanese and South-East Asian lunar calendar.
The study examines the earliest Chinese translations of the life of the Buddha (Xiuxing benqi jing, Taizi ruiying benqi jing) and other Chinese primary sources describing the cerimonies commemorating the birth of the Buddha, as well as a selection of bronze statuettes and stone reliefs from China datable from the 2nd to 5th centuries and others items from Korea and Japan
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