1,720,984 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Vooruitgang in de microputjestechnologie: van nieuwe strategieën voor microfabricatie tot individuele partikel manipulaties
No full textOver the years, we witnessed impressive progress in the field of biosensor technology with numerous successful applications for life science research, medical diagnostics and industrial processes. A lot of research effort has been made to achieve better analytical sensitivities with single-molecule resolution as the ultimate goal. Such ultrasensitive detection platforms are extremely valuable for the early detection of low-abundance disease-relevant biomarkers as well as for screening heterogenic sample populations. In particular, bead-based microwell arrays have proven its potential for target detection with single-molecule resolution, by spatially confining individual targets in microwells.
The success of ultrasensitive bead-based microwell array technology is exemplified by the commercial applications of Illumina (i.e. BeadArray™) and Quanterix (i.e. SiMoA™) for nucleic acid analysis and ultrasensitive protein measurements, respectively. High-efficiency seeding of magnetic beads is key for the success of these applications and can be enhanced by the creation of hydrophilic-in-hydrophobic (HIH) microwell arrays. However, the fabrication of HIH microwell arrays requires complex and labour-intensive procedures and consequently calls for simpler manufacturing methods.
Additionally, current bead-based microwell array systems are restricted solely to target detection, not allowing subsequent manipulation of single beads with captured targets of interest. Although various bead-based trap-and-release systems have already been developed for manipulation of interesting targets at the single-molecule level, they either release all trapped beads at once or in a sequential manner. These platforms thus require an integrated sorting unit, which separates those beads that have captured an interesting target from the rest of the beads. Hence, there is a need for a multipurpose ultrasensitive bead-based trap-and-release system that would enable both detection and manipulation of interesting target molecules. Such platforms would be of special interest for single-cell applications, bacteria screening, drug discovery and antibody therapeutics.
Therefore, the aim of this dissertation, is to (i) establish a multipurpose platform for both detection and manipulation of single molecules by integrating an optical manipulation tool (for retrieving single magnetic beads) with the digital microfluidic-based microwell array, and (ii) evaluate an innovative microwell array fabrication method for the swift manufacturing of HIH microwell arrays.
The first part of this work focused on the integration of optical tweezers with an electrowetting-on-dielectric-based digital microfluidic microwell array system for the manipulation of single magnetic beads, seeded in a microwell array. Optical manipulation of seeded magnetic beads required their Brownian motion. To this end, the optimal experimental design approach was used for studying and identifying optimal buffer conditions, which generated high fractions of seeded beads with Brownian motion and thus enabled successful manipulation of single magnetic beads. Six different buffer parameters, including bead type, ionic buffer strength, pH, non-ionic surfactant type and concentration, were investigated in this experiment. The analysis of this optimal experimental design indicated different optimal buffer conditions for carboxylated and streptavidin-coated beads, with Tween 40 and Tween 60 as the best non-ionic surfactants. Using these optimized buffer conditions, multiple bead manipulations, including bead retrieval, trapping, transporting and repositioning in another microwell, were successfully demonstrated.
In the second part, the potential of a novel hydrophobic off-stoichiometric thiol-ene-epoxy polymer formulation was explored for imprinting HIH microwell arrays, using a stamp-moulding technique. With this method, HIH microwell arrays were created with excellent dimensions and topological features, enabling highly efficient printing and seeding of superparamagnetic beads. Using streptavidin-biotin interaction and β–galactosidase as a reporter enzyme, a digital bioassay was performed. A detection limit of 17.4 attomolar was obtained, demonstrating the potential of the imprinted microwell arrays to perform sensitive digital bioassays. Hence, it can be concluded that the novel hydrophobic Off-stoichiometric Thiol-Ene-Epoxy polymer and the integration of optical tweezers in the electrowetting-on-dielectric-based digital microfluidic microwell array system have a huge potential for the development of new commercial digital ELISA and bead-based trap-and-release system, respectively.status: Publishe
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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