5,746 research outputs found

    I Remember column in which author Eva LaPlante writes of her visits to sites a

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    I Remember column in which author Eva LaPlante writes of her visits to sites associated with E. B. White and his book Charlotte\u27s Web

    Eva Murray, author of Well Out to Sea , has been a resident of Matinicus Island

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    Eva Murray, author of Well Out to Sea , has been a resident of Matinicus Island since she moved there to teach at the island\u27s one-room schoolhouse in 1987. She discusses the differences between writing from an island and writing about an island as well as her efforts to dispel some stereotypes and myths about Matinicus through her writing

    Mekanisme Molekuler Dari Resistensi Insulin Pada Diabetes Melitus Tipe Dua

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    Diabetes melitus merupakan kelainan endokrin yang paling sering ditemukan. Salah satu patofisiologi utamanya adalah resistensi jaringan target terhadap insulin. Pada tahap seluler, resistensi insulin adalah adanya kemampuan yang tidak adekuat dari insulin signaling pada reseptor insulin terhadap molekul pada proses aksi insulin. Sekuensi patofisiologi yang tepat yang menyebabkan resistensi insulin masih belum banyak diketahui. Tujuan: Untuk mengetahui mekanisme molekuler dari resistensi insulin pada diabetes melitus tipe dua. Metode: Artikel ini ditulis berdasarkan studi kepustakaan yang berhubungan dengan mekanisme molekuler dari resistensi insulin pada diabetes melitus tipe dua. Hasil:  Banyak molekul yang terlibat dalam pengolahan intraseluler dari insulin signaling yang diperankan oleh insulin, IRS-2, PKB, protein Foxo dan P85 subunit PI-3 kinase. Disfungsi-disfungsi dari molekul ini menyebabkan resistensi insulin in vivo. Identifikasi defek signaling dan pemahaman hubungan kompleks dari faktor yang berbeda dalam memodulasi sensitivitas insulin yang merupakan prasyarat penting untuk pengembangan senyawa anti-diabetes baru dan lebih spesifik. Simpulan: Dengan menjelaskan mekanisme molekuler pada insulin signaling yang bertanggung jawab untuk resistensi insulin, dapat dipahami sebagian besar dari resistensi insulin secara molekuler

    Obesity of Older School Age Children Based on Physical Activity and Eating Habits

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    TITLE: Obesity of Older School Age Children Based on Physical Activity and Eating Habits AUTHOR: Bc. Eva Lamačová DEPARTMENT: Department of Education SUPERVISOR: PaedDr. Eva Marádová, CSc. ABSTRACT: This thesis deals with the obesity of older school age children and their dependence on eating and exercising habits. The theoretical part summarizes knowledge regarding overweight and obesity, disease diagnosis, epidemiological trends and complications related to obesity. Emphasis is put on the evaluation of reasons to why this problem occurs, such as disease prevention, dietary and exercise recommendations, its therapy and inclusion of the issue with the secondary school curriculum. The practical part contains research focused on the nutritional status, eating and exercise habits of pupils in secondary school. The survey results are designed for use in pedagogical practice. Usage is targeted for obesity prevention in this age group during Physical Education and Health Education subjects. KEYWORDS: Obesity, overweight, eating habits, exercising habit

    KADAR APOLIPOPROTEIN B 100 SERUM PADA PENDERITA NEFROPATI DIABETIKUM

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    AbstrakPenelitian ini bertujuan untuk mengetahui kadar Apolipoprotein B 100 serum pada penderita nefropati diabetikum. Metode penelitian ini dengan desain cross sectional yang bersifat deskriptif analitik. Populasi adalah semua pasien yang menderita diabetes mellitus tipe 2 yang dirawat di bagian penyakit dalam atau kontrol ke poliklinik khusus metabolik endokrin RSU Dr. M. Djamil Padang. Sampel penelitian adalah pasien diabetes mellitus tipe 2 dengan proteinuria positif yang memenuhi kriteria inklusi dan ekslusi yang diambil secara konsekutif. Sampel penelitian diambil dari darah vena dalam keadaaan puasa selama 12 jam. Pemeriksaan apolipoprotein B 100 serum dilakukan di laboratorium klinik swasta, dengan menggunakan metode imunoturbidimetri. Albumin creatinin ratio merupakan perbandingan kadar albumin urin terhadap kreatinin urin dengan metode pemeriksaan imunoturbidimetri. Pada penelitian ini didapatkan rerata kadar Apolipoprotein B 100 serum yaitu 86,10 mg/dl (nilai normal 66-101 mg/dl) dengan standar deviasi 27,997. Simpulan: Tidak terdapat peningkatan kadar apolipoprotein B 100 serum pada penderita nefropati diabetikum.AbstractThis study aims to examine Apolipoprotein B 100 serum level in diabetic nephropathy patient. Study design was cross sectional with analytic descriptive. Population is all type 2 diabetes mellitus inpatient and outpatient in internal medicine M Djamil hospital. Sample is all type 2 diabetes mellitus consecutive patient with positive proteinuria and fullfilled inclusion and exclusion criteria. Vein blood was taken after 12 hours-fasting. Apolipoprotein B 100 serum check at non-governmental laboratory by immunoturbidimetry methode. Albumin creatinin ratio check by immunoturbidimetry methode. Result: Apolipoprotein B 100 serum level is 86.10 mg/dl (normal value 66-101 mg/dl) with standar deviation 27.997. Conclusion: There is no significant enhancement of apolipoprotein B 100 serum level in diabetic nephropathy patient.<br /

    ANALISIS PENDEKATAN ECONOMIC VALUE ADDED (EVA) TERHADAP KINERJA KEUANGAN PADA PERUSAHAAN MAKANAN DAN MINUMAN DI BURSA EFEK INDONESIA

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    Economic Value Added (EVA is one approach to measuring the financial performance of a company by focusing on the creation of value-added enterprises. EVA shows how big the resulting rate of return on the investment made by shareholders. In this paper, the object used by the author is wrong a company engaged in the food and beverage industry in Indonesia Stock Exchange. data used is the consolidated financial statements of the company in 2011-2012. purpose of this paper is to measure the financial performance of the EVA approach to food and beverage companies 2011-2012. Results analysis of the EVA calculation shows that by using the EVA approach, the financial performance of food and beverage companies can experience a volatile period 2011-2012. In 2011 the company's financial performance has improved food and beverage d in the presence of EVA is positive that the company has succeeded in achieving its goal create value-added enterprises. But in 2012 the company's food and beverage show poor financial performance since EVA generated negative worth. This means that in 2012, the company has not been able to create value for the rate of return expected by shareholders or the investment made. Keywords: Economic Value Added (EVA

    Iskemia pada Jari Tangan Penderita Diabetes Melitus: Suatu Keadaan Peripheral Arterial Disease

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    Abstrak Pendahuluan: Peripheral Arterial Disease (PAD) adalah penyumbatan pada arteri perifer akibat proses atherosklerosis atau proses inflamasi yang menyebabkan lumen arteri menyempit (stenosis), atau pembentukantrombus. Tempat tersering terjadinya PAD adalah daerah tungkai bawah dan jarang ditemukan pada jari tangan.Metode: Laporan kasus. Hasil: Telah dilaporkan suatu kasus iskemia jari tangan yang jarang ditemui di klinik, merupakan suatu PAD. Pembahasan: Selain adanya faktor risiko konvensional seperti diabetes melitus dan keganasan untuk terjadinya trombosis, juga didapatkan suatu kelainan herediter berupa defisiensi antikoagulan yaitu defisiensi protein S, sekalipun protein C dalam batas normal yang secara bersama-sama diduga mempermudah terjadinya trombosis pada arteri perifer. Kata kunci: Diabetes, Iskemia, Peripheral arterial disease, Protein S, Trombosis Abstract Introduction: Peripheral Arterial Disease (PAD) is occlusion in peripheral artery caused by atherosclerosis or inflammation process that make stenosis in artery, or thrombus formation. High incidence of PAD occur in lower extremity, and rarely in hand and finger. Method: Case report. Result: Has been reported hand ischaemia that rarely found in hand and finger. Discussion: Despite conventional risk factor for thrombosis like diabetes mellitus and malignancy, hereditary disorder of anticoagulant factor deficiency played the same role, like protein S deficiency,eventhough protein C in normal limit. These risk factors made thrombosis at peripheral arteri easier to occur.Keywords:  Diabetes, Ischaemia, Peripheral arterial disease, Protein S, Thrombosis<br /

    Krisis Tiroid pada Wanita Multipara Usia 42 Tahun

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    Krisis tiroid selama kehamilan dapat mengancam nyawa ibu maupun janin. Kematian pada ibu disebabkan karena terjadinya henti jantung dan kematian janin disebabkan oleh keguguran, berat badan lahir rendah, kelahiran premature, preeklamsi dan malformasi kongenital. Dilaporkan seorang wanita multipara 42 tahun yang telah dikenal hipertiroid datang dengan penurunan kesadaran sejak 1 hari sebelum masuk rumah sakit, usia kehamilan 20 minggu. sebelumnya pasien mengeluhkan palpitasi, demam, berkeringat, tremor, diare, dan sesak nafas. Berdasarkan pemeriksaan fisik, pasien tampak delirium, dengan tekanan darah 110/50 mmHg, nadi 115 kali/menit, dan suhu 38,4oC. Pada pemeriksaan mata tampak Rosenbach dan Enroth. Tanda oftalmopati Graves adalah NOSPEC 1. Berdasarkan palpasi kelenjar tiroid, ukuran 9 x 5 x 2 cm, difus, dan simetris.Pada pemeriksaan fisik ditemukan kardiomegali dan hepatomegali. Skor index Wayne adalah 22 (hipertiroid) dan Skor Burch dan Wartofsky adalah 60 (krisis tiroid). Pemeriksaan laboratorium menunjukkan kadar FT4 43,49 pmol/L, tyroid-stimulating hormone (TSH) 0,1 UIU/mL, dan peroksida anti-tiroid (anti-TPO) 0,31 IU/mL (negatif). Pemeriksaan USG tiroid menunjukkan struma difusa. Pasien mendapat terapi 600 mg PTU dan diikuti dengan 200 mg PTU empat kali sehari. Propanolol 40 mg sehari, Deksametason 40 mg sehari melalui intravena, dan Iodin Lugol empat kali sehari. Selama pengobatan, kondisi klinis pasien membaik, krisis tiroid teratasi dan keadaan janin dalam keadaan baik

    Eva Urban. 'Lessing’s Nathan the Wise: from the Enlightenment to the Berliner Ensemble.'

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    Lessing's Nathan the Wise (1779), exemplary for its enlightenment and humanist ideals, assembles Jews, Christians, and Muslims in dialogue during the medieval crusades in Jerusalem. Their encounters allow them to transcend conflict, to recognize their common humanity, and to resolve their differences through dialectical discourse and group arguments. In this article Eva Urban looks closely at the representation of enlightenment in this play and examines the potential role of plays and theatre practice in developing autonomous citizenship and intercultural understanding. Particular reference is made to the 2013 Berliner Ensemble production of Nathan the Wise in relation to aesthetic debates about modern political drama. Eva Urban is a British Academy Postdoctoral Research Fellow at the Faculty of English, University of Cambridge, and an Associate of Clare Hall, Cambridge. She is the author of Community Politics and the Peace Process in Contemporary Northern Irish Drama (Peter Lang, 2010) and has published a number of articles on political drama and Irish studies
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