6,156 research outputs found

    HCV Diversity among Chinese and Burmese IDUs in Dehong, Yunnan, China

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    HCV transmission is closely associated with drug-trafficking routes in China. Dehong, a prefecture of Yunnan, is the important trade transfer station linking Southeast Asia and China, as well as the drug-trafficking channel linking “Golden triangle” and other regions of China and surrounding countries. In this study, we investigated the HCV genotype diversity among IDUs in Dehong based on 259 HCV positive samples from 118 Chinese and 141 Burmese IDUs. HCV genotypes were determined based on the phylogenies of C/E2 and NS5B genomic sequences. Six HCV subtypes, including 1a, 1b, 3a, 3b, 6n and 6u, were detected. Interestingly, 4 HCV sequences from Burmese IDUs did not cluster with any known HCV subtypes, but formed a well-supported independent clade in the phylogenetic trees of both C/E2 and NS5B, suggesting a potential new HCV subtype circulating in Dehong. Subtype 3b was the predominant subtype, followed by subtypes 6n and 6u. Comparison showed that Dehong had a unique pattern of HCV subtype distribution, obviously different from other regions of China. In particular, HCV subtypes 6u and the potential new HCV subtype had a relatively high prevalence in Dehong, but were rarely detected in other regions of China. There was no significant difference in HCV subtype distribution between Burmese and Chinese IDUs. Few HCV sequences from Burmese and Chinese IDUs clustered together to form transmission clusters. Furthermore, about half of HCV sequences from Burmese IDUs formed small transmission clusters, significantly higher than that from Chinese IDUs (p</div

    Unfolding of Population Structure in Dehong Buffalo Using Microsatellite DNA Markers

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    Dehong buffalo are an indigenous buffalo breed in Yunnan province, China. A total of 81 unrelated samples from Dehong buffalo breeds were genotyped using 15 microsatellite DNA markers from 14 chromosomes to estimate genetic diversity, genetic differentiation and gene flow within populations. A total of 62 alleles were detected across the 15 loci assayed. All the loci were polymorphic and the number of alleles ranged from two to six, giving a mean number of 4.13 alleles per locus. The expected heterozygosity and polymorphism information content of 15 microsatellite loci were 0.6520±0.1526 and 0.5863±0.1789, respectively. Coefficients of genetic differentiation ranged from 0 to 0.0919, with the average of 0.0202. Gene flow at each locus was large, with a mean Nm of 12.1502. The results indicated that the genetic diversity was rich among Dehong buffalo and the genetic differentiation in its sub-populations was relatively low, with larger gene flow and less inbreeding

    Tang Code, Tang Rite, and Other Manuscripts of Tang Dynasty

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    In the present paper, the author gives the preliminary reports on three newly found Tang 唐 official documents, pointing out their important value, and offering the all texts for further studies.1. In Tunhuang and Turfan Documents concerning Social and Economic History I. Legal Texts (Tokyo 1978-1980), Professors T. Yamamoto, O. Ikeda, and M. Okano published the joined texts of O. 5098 and O. 8099 from Otani collection. They identified the fragments with the Section on Violence and Robbery of the Tang Code (唐律), and pointed out the article comes from the Yonghui 永徽 or Chuigong 垂拱 Code according to the Zetian 則天 characters used in the Buddhist text on the verso. The author joins another fragment based on an old photograph of the Turfan document preserved in the Lüshun Museum (旅順博物館). The new text contains one different article from the printed text after the Song 宋 dynasty.2. Among the Dunhuang 敦煌 manuscripts in the National Library of China in Beijing, there is a good copy of the Tang Rite (唐礼) in high Tang characters (No. zhou 周 70A). It contains the text corresponding to the Da Tang Kaiyuan li 大唐開元礼, vol. 37: “Huangdi shixiang yu Taimiao 皇帝時享於太廟”. It is the first time to find the book in Dunhuang or Turfan manuscripts.3. In his Dunhuang Turfan Tangdai fazhi wenshu kaoshi 敦煌吐魯番唐代法制文書考釈, Liu Junwen thought the document of zhou 51 should be the Regulations of the Regional Military Organization. But the form of the original document could not conform to the Tang Regulations, so the author refutes his view and thinks that it is an official document relating to the beacon of the military fortress in the area of Dunhuang or Turfan.journal articl

    Tang O 1950-1954

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    A report on the village of Tang O, detailing its location, the current projects there, and the resources available

    Epidemiological investigation of thalassemia in gestational age population of Dai nationality in Dehong Prefecture, Yunnan Province

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    Objective To investigate the gene carrying rate,gene mutation type and hematological characteristics of thalassemia in Dai nationality population of Dehong Prefecture, Yunnan Province. Methods A total of 591 Dai nationality gestational age population in Dehong were tested for thalassemia gene by next-generation sequencing technology. The sensitivity and specificity of the hemoglobin electrophoresis and blood routine tests were performed. Results A total of 289 cases (48.90%) were positive for thalassemia gene. Among them,231 cases were classified as α-thalassemia(39.09%) and 89 cases were β-thalassemia(15.06%). Five α-thalassemia genotypes and seven β-thalassemia genotypes were detected. For α-thalassemia, --SEA showed comparatively lower values for MCV and MCH; αCSα showed comparatively lower values for Hb A2 (P<0.05). For the β-thalassemia,CD 26 (G>A)had significantly lower Hb A values,and higher MCH values(P<0.05). A new cut-off value for the thalassemia with the highest accuracy was proposed(MCV 83.55 fL,MCH 27.95 pg). Conclusions Thalassemia is common in Dai nationality population of Dehong. The most frequently identified types are -α3.7 and CD 26 (G>A)

    Reinventing the Pre-Tang Tradition: Compiling and Publishing Pre-Tang Poetry Anthologies in Sixteenth-Century China

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    Abstract This article examines how the making of pre-Tang poetry anthologies in sixteenth-century Ming China led to a reinvention of the pre-Tang poetic tradition. From the Zhengde period 正德 (1506–21) well into the Wanli reign 萬曆 (1573–1620), the compilation and publication of new pre-Tang poetry anthologies saw a dramatic increase, making the anthologizing practices in the 1500s crucial to understanding the pre-Tang tradition. Through a study of paratextual elements (book titles, tables of contents, prefaces, postscripts, etc.) in twenty-two pre-Tang poetry anthologies compiled in the 1500s, this article identifies three types of anthologizing practices. By employing quantitative and network analysis, the author hopes to historicize these practices, investigate the motivations for the anthologies, and explore their citation networks. These anthologizing practices, I conclude, gradually transformed the classification principles of previous anthologies, expanded the scope of canonized anthologies, and established a distinct pre-Tang tradition by the end of the sixteenth century.</jats:p

    Screening and analysis of HCV among drug users in Dehong Prefecture, Yunnan Province from 2014 to 2021

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    ObjectiveTo analyze the prevalence of HCV antibody positive and associated factors among drug users in Dehong Prefecture, Yunnan, and to provide scientific evidence for HCV prevention.MethodsQuestionnaire surveys and serological testing were conducted among 400 drug users continuously selected from four national AIDS sentinel surveillance in Dehong Prefecture between January and July during 2014‒2021.Results11 683 drug users were included. The prevalence of HCV antibody positive was 20.2% overall, and 14.9%, 20.1%, 22.4%, 19.8%, 22.5%, 20.6%, 24.5%, 19.0% from 2014 to 2021, respectively (trend Z=-3.78, P<0.001). Multivariable analysis indicated the following were independently associated with HCV antibody positive: that older age (OR=1.02, 95%CI: 1.02‒1.03), male (OR=1.70, 95%CI: 1.19‒2.42), unmarried (OR=1.64, 95%CI: 1.44‒1.87), divorced or widowed (OR=1.73, 95%CI: 1.48‒2.02), Jingpo ethnicity (OR=1.39, 95%CI: 1.19‒1.63), injection drug use (OR=15.46, 95%CI: 13.13‒18.12), and HIV infection (OR=4.96, 95%CI:4.12‒5.99).ConclusionThe prevalence of HCV antibody positive among drug users in Dehong Prefecture is high and increases with some fluctuations during 2014 to 2021, which highlights the need to develop interventions targeting this population
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