1,720,963 research outputs found
High-resolution crystal structure of the recombinant diheme cytochrome c fromShewanella baltica(OS155)
No full textMultiheme cytochromes c (cyts c) are c-type cyts characterized by non-standard structural and spectroscopic properties. The relative disposition of the heme cofactors in the core of these proteins is conserved and they can be classified from their geometry in two main groups. In one group the porphyrin planes are arranged in a perpendicular fashion, while in the other they are parallel. Orientation of the heme groups is a key factor that regulates the intramolecular electron transfer pathway. A 16.5 kDa diheme cyt c, isolated from the bacterium Shewanella baltica OS155 (Sb-DHC), was cloned and expressed in E. coli and its structure was investigated by X-ray crystallography. Using high-resolution data (1.14 Å) collected at ELETTRA (Trieste), the crystal structure, with an orthorhombic cell (a = 40.81, b = 42.97, c = 82.07 Å), was solved using the homologous diheme from Rhodobacter sphaeroides (Rs-DHC) as the initial model. The electron density map of the refined structure (Rfact of 13.8% and Rfree of 15.4%) shows a two domain structure connected by a central unstructured region (N72-G87). The Sb-DHC, like its homologue (Rs-DHC), folds into a new cyt c class: the N-terminal globular domain, with its three α-helices, belongs to class I of c-type cyts, while the C-terminal domain includes a rare π-helix. The metal centre of the c-type heme groups is axially coordinated by two His residues and it is covalently bound to the protein through two Cys bonds
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Resti di fauna dai pozzetti neolitici di Gazzo Veronese (VR) - loc. Scolo Gelmina: risultati preliminari dell’analisi tafonomia.
No full textIl sito neolitico di Gazzo Veronese in località Scolo Gelmina (VR) è stato oggetto di uno scavo archeologico da parte della Soprintendenza per i beni archeologici del Veneto nel 1997. Sono state identificate 26 strutture negative e 2 tombe ad incinerazione. Attraverso l’analisi del materiale ceramico in esse contenuto, è stato possibile riferire 24 pozzetti al Neolitico recente, ed in particolare ad una fase arcaica della terza facies della Cultura dei Vasi a Bocca Quadrata (VBQ III). L’analisi tassonomica e tafonomica preliminare dei resti faunistici provenienti da tali strutture ha permesso di ipotizzare l’economia del sito. I taxa più rappresentati sono Bos taurus, Sus scrofa, Capra vel Ovis. Le tracce antropiche sono state riscontrate su un numero limitato di resti (6,6%) ma sono presenti sulla quasi totalità delle porzioni anatomiche. Esse attestano le varie fasi del trattamento della carcassa animale, suggerendo che la macellazione sia avvenuta all’interno del sito nella zona circostante i pozzetti
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
I resti faunistici dai pozzetti neolitici di Gazzo Veronese - Località Scolo Gelmina (VR). Risultati preliminari dell’analisi tafonomica
No full textRIASSUNTO - Il sito neolitico di Gazzo Veronese in località Scolo Gelmina (VR) è stato oggetto di uno scavo archeologico da parte della Soprintendenza per i Beni Archeologici del Veneto nel 1997. Sono state identificate 26 strutture negative e 2 tombe ad incinerazione. Attraverso l’analisi del materiale ceramico in esse contenuto, è stato possibile riferire 24 pozzetti al Neolitico recente, ed in particolare ad una fase arcaica della terza facies della Cultura dei Vasi a Bocca Quadrata (VBQ III). L’analisi tassonomica e tafonomica dei resti faunistici, provenienti da tali strutture, ha permesso di ipotizzare l’economia del sito. I taxa più rappresentati sono Bos taurus, Sus scrofa, Ovis vel Capra. Le tracce antropiche sono state riscontrate su un numero limitato di resti (6,6%) ma sono presenti sulla quasi totalità delle porzioni anatomiche. Esse attestano le varie fasi del trattamento della carcassa animale, suggerendo che la macellazione era avvenuta all’interno del sito nella zona circostante i pozzetti.ABSTRACT - The neolithic site of Gazzo Veronese - località Scolo Gelmina (Verona) was excavated by Soprintendenza per i Beni Archeologici del Veneto in 1997. 26 negative structures and 2 incineration tombs have been brought to light. Through the analysis of the material found in the pits, it has been possible to relate 24 structures to the recent Neolithic, and specifically to the third phase of the Squared Mouthed Pottery Culture (SMP III). The taxonomic and taphonomic analysis of the faunal specimens made possible to retrace the site economy. The most represented species are Bos taurus, Sus scrofa, Ovis vel Capra. The anthropic marks have been recognized on a scarce number of remains (6.6%) but they have been observed almost on every anatomical portions. They attest the different phases of the butchery, suggesting that it happened inside the settlement nearby the pits
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