15 research outputs found
Digital evolution of ERP: Capabilities, definition and research agenda
No full textMany organizations have a long history with the use of ERP. However, organizations are increasingly turning to digital capabilities to transform operational processes and business models. Extant literature has increased our under-standing of ERP, but we lack comprehensive insights into the evolving nature of ERP in the context of digital transformation. Through a review of articles from the AIS Basket of Eight IT journals, we identified digital capabilities associated with contemporary ERP across five categories. The identified capabilities fore-ground the evolving nature of ERP, resulting in the introduction of a definition for digital ERP (D-ERP) and a call for research studying the co-evolution of D-ERP and digital transformation
Toward digital ERP : a literature review
No full textMany organizations have a long history with the use of ERP. However, organizations are increasingly turning to digital capabilities to transform operational processes and business models. Extant literature has increased our understanding of ERP, but we lack comprehensive insights into the evolving nature of ERP in the context of digital transformation. Through a review of articles from the AIS Basket of Eight IT journals, we identified digital capabilities associated with contemporary ERP across five categories. The identified capabilities foreground the evolving nature of ERP, resulting in the introduction of a definition for digital ERP (D-ERP) and a call for research studying the co-evolution of D-ERP and digital transformation
Digital evolution of ERP: Capabilities definition and research agenda
No full textMany organizations have a long history with the use of ERP. However, organizations are increasingly turning to digital capabilities to transform operational processes and business models. Extant literature has increased our under-standing of ERP, but we lack comprehensive insights into the evolving nature of ERP in the context of digital transformation. Through a review of articles from the AIS Basket of Eight IT journals, we identified digital capabilities associated with contemporary ERP across five categories. The identified capabilities fore-ground the evolving nature of ERP, resulting in the introduction of a definition for digital ERP (D-ERP) and a call for research studying the co-evolution of D-ERP and digital transformation
El convento de Jericó en Bruselas y su red literaria
No full textThe Augustinian convent of Jericho in Brussels was one of the main centres of textual, literary, and spiritual culture in the late medieval Low Countries. In addition to the large collection of manuscripts which the canonesses wrote for themselves, the sisters produced several books for people and institutions outside the convent walls. Thus the sisters were both important recipients as well as signifi cant producers of texts. This article will focus on the question of the origin of the texts and books that the sisters used to build their library. Additionally, attention will be paid to the external recipients of the books that the Jericho scribes made, in order to shed light on the as yet understudied exchange of texts and books to and from (female) convents and the literary networks in which these religious institutions functioned.El convento de las agustinas Jericó en Bruselas fue uno de los centros más importantes de la cultura textual, literaria, y espiritual en los Países Bajos durante la Baja Edad Media. Además de la amplia colección de manuscritos que las canonesas escribieron para sí mismas, produjeron varios libros para personas e instituciones externas al convento. Las religiosas no solo eran receptoras importantes, sino también signifi cativas productoras de textos. El artículo se concentra en la cuestión de la proveniencia de los textos y libros que servían para crear su biblioteca. Se prestará asimismo atención a los destinatarios externos a los que se dirigieron las copistas de Jericó con el fin de arrojar luz sobre la hasta ahora poco estudiada dinámica de intercambio de textos y libros entre conventos (de mujeres) y el exterior y las redes literarias en el marco de las cuales esas instituciones religiosas funcionaron
Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export
No full textThe NS1 protein of influenza virus is a major virulence factor essential for virus replication, as it redirects the host cell to promote viral protein expression. NS1 inhibits cellular messenger ribonucleic acid (mRNA) processing and export, down-regulating host gene expression and enhancing viral gene expression. We report in this paper the identification of a nontoxic quinoline carboxylic acid that reverts the inhibition of mRNA nuclear export by NS1, in the absence or presence of the virus. This quinoline carboxylic acid directly inhibited dihydroorotate dehydrogenase (DHODH), a host enzyme required for de novo pyrimidine biosynthesis, and partially reduced pyrimidine levels. This effect induced NXF1 expression, which promoted mRNA nuclear export in the presence of NS1. The release of NS1-mediated mRNA export block by DHODH inhibition also occurred in the presence of vesicular stomatitis virus M (matrix) protein, another viral inhibitor of mRNA export. This reversal of mRNA export block allowed expression of antiviral factors. Thus, pyrimidines play a necessary role in the inhibition of mRNA nuclear export by virulence factors
Explorative and exploitative learning strategies in technology-based alliance networks
No full textalliance, networks
Understanding the adoption and use of information systems/information technology in small and medium-sized manufacturing enterprises : a study in Portuguese industry.
No full textThis research analysed factors and sets of factors that affect and explain the varying levels
of success in the adoption and use of IS/IT (Information Systems/Information Technology)
in Portuguese manufacturing SMEs (Small and Medium-sized Enterprises). The study set
out to fill a gap in knowledge not covered by previous research into the area of IS/IT in
SMEs. Existing work was found to be of limited relevance or was out-of-date, due to the
rapid evolution of IS/IT, and did not address the Portuguese context.
The study followed a realist approach to social enquiry. Seeking to explain IS/IT success, it
is necessary to understand the perspectives and social relationships amongst the key actors
involved in the process of IS/IT adoption and use. Case study research was undertaken in
twelve SMEs operating in the Portuguese manufacturing industry. A total of 56 interviews
were conducted with top managers, IS/IT managers, IS/IT staff, and IS/IT suppliers. The
factors identified as associated with IS/IT success were clustered into four categories
according to their perceived relevance. Interrelationships amongst factors were established
and the common patterns across firms with similar levels of IS/IT adoption and success
were analysed.
This research demonstrates that a combination of factors were determinant to explain IS/IT
adoption and success. These are related to the involvement of the top managers in the
process of IS/IT adoption and use, and to the development of IS/IT competencies, in-house
or in associated IS/IT suppliers. Of particular importance is the presence of an individual in
the firm with IS/IT knowledge, CEO trust, and a view on how to incorporate IS/IT in the
strategic development of the firm. In the SMEs that were more successful in adopting and
using IS/IT, the establishment of co-operative links with IS/IT suppliers was essentially
based on personal relationships or ownership of the IS/IT enterprise, rather than on
contractual relationships. The findings were validated by comparison with existing theory,
and resource-based theory was found to provide a coherent explanation of the results of the
empirical work
SYNTHESIS OF p-PHENYLENE VINYLENE DENDRONS & THEIR FUNCTIONALIZATION AND TESTING IN DYE-SENSITIZED SOLAR CELLS
No full textThe novel synthesis of p-phenylene vinylene dendrons utilizing a Horner-Wadsworth-Emmons based approach is described. The extended, linear π conjugation along all the dendron branches, a feature absent in most dendrimers used for light harvesting, was expected to lead to an efficient light-harvesting system by acting as a dendritic molecular wire between peripheral donor chromophores and a core acceptor. To that end, nickel porphyrins were added to the
periphery of the dendrons as preparation for inclusion in dye-sensitized solar cells. The prepared dendron-porphyrin conjugates proved to be poor dyes. This disappointing result is attributed to the use of nickel porphyrins which were found to undergo non-radiative decay, making them
unsuitable for light-harvesting applications. Changes to the system are proposed, from replacing the nickel with zinc within the porphyrins to the use of alternative chromophores, to better test the dendrons function as molecular wires
