1,721,110 research outputs found

    Lateral ridge augmentation using an equine flex bone block infused with recombinant human platelet-derived growth factor BB: A clinical and histologic study

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    This paper reports on a patient who underwent horizontal ridge augmentation using recombinant human platelet-derived growth factor BB (rhPDGF-BB) in combination with a collagenate equine block. Ninety days after the first surgery, 8 mm of new bone was noted on a computed tomography scan, and three 5-mm implants were placed. Histology, performed using confocal laser scanning microscopy, showed a large amount of newly formed bone well characterized with osteon and resorption lacunae, which demonstrated the intense bone remodeling. This study supports the use of rhPDGF-BB in combination with allograft blocks. © 2011 by Quintessence Publishing Co Inc

    Efficacy of the lateral advanced flap in root-coverage procedures for mandibular central incisors: A 5-year clinical study

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    The aim of this study was to determine the efficacy of the lateral advanced flap in root-coverage procedures for mandibular incisors and to evaluate pain after treatment. A total of 15 patients who required treatment for gingival recessions were selected from the University of Genoa Laser and Restorative Dentistry Department. The inclusion criteria were the presence of at least one 3-mm gingival recession defect of a mandibular incisor and 3 mm or more of keratinized tissue width on the immediately adjacent tooth. One calibrated masked examiner performed the clinical measurements, including recession depth and width, probing depth, clinical attachment level, and keratinized tissue width. Patients were checked 7, 14, and 30 days after surgery and were included in supportive periodontal maintenance every 4 months. Further follow-ups were done at the first, third, and fifth year postsurgery when the same baseline assessment parameters were recorded according to the root-coverage esthetic score (RES). Numeric score recorded pain evaluations showed a mean of 3 at the day of the surgery, 2 in the first day after the surgery, and no significant scores were referred in the following days. Mean recession depth was 3.2 ± 1.3 mm at baseline; at 5 years, RES showed a positive increase of all scores. The laterally coronally advanced surgical technique was very effective in treating isolated gingival recessions. It combined the esthetic and root-coverage advantages of the coronally advanced flap with the increased gingival thickness and keratinized tissue associated with the lateral gingival flap

    Evaluation of Prosthetic Marginal Fit and Implant Survival Rates for Conventional and Digital Workflows in Full-Arch Immediate Loading Rehabilitations: A Retrospective Clinical Study

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    Digital impression provides several advantages in implant prosthodontics; however, its use in full-arch rehabilitations, especially immediately after surgery, has yet to be validated. The aim of this study was to retrospectively analyse the fit of immediate full-arch prostheses, fabricated using conventional or digital impressions. Patients requiring a full-arch immediate loading rehabil- itation were divided into three groups: T1 (digital impression taken immediately after surgery), T2 (Preoperative digital impression, guided surgery -prefabricated temporary bridge) and C (conventional impression taken immediately after surgery). Immediate temporary prostheses were delivered within 24 h after surgery. X-rays were obtained at the time of prosthesis delivery and at the 2 - year follow-up. Primary outcomes were cumulative survival rate (CSR) and prosthesis fit. Second- ary outcomes were marginal bone level (MBL) and patient satisfaction. One hundred and fifty pa- tients were treated from 2018 to 2020, with 50 in each group. Seven implants failed during the ob- servation period. The CSR was 99% for T1, 98% for T2 and 99.5% for C. A statistically significant difference in prosthesis fit was found among T1 and T2 vs. C. A statistically significant difference was found in the MBL between T1 and C. The outcomes of the present study suggest that digital impression is a viable alternative to conventional protocols for the realisation of full-arch immediate loading prostheses

    Expansion of the Zone of Keratinized Tissue for Healthy Implant Abutment Interface Using De-epithelialized Amnion/Chorion Allograft

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    Keratinized tissue around implants is beneficial for soft tissue stability and esthetics. The aim of this investigation is to show the use of amnion/chorion membrane to increase the keratinized tissue. Fifteen patients were grafted with the allograft at the first or second stage of implant surgery. The mean values of keratinized tissue were 1.27 ± 0.46 mm, 2.00 ± 0.38 mm, 2.80 ± 0.78 mm, and 3.27 ± 0.80 mm at the initial evaluation and 7, 15, and 60 days postsurgery (prosthetic delivery was at day 60), respectively (P <.001). Most increase occurred between 7 days up to the prosthetic delivery. Use of the amnion/chorion membrane seems to improve keratinized-tissue expansion

    Dental implants surface roughness can influence bacterial site infection? A clinical in vivo prospective clinical study on 109 patients, preliminary results on radiologic evaluation.

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    Dental implants are intended to provide long-term reliable dental restorations. Limited data exist on the comparison between different implant surfaces. This study aims to investigate if the surface topography and roughness might increase the bacterial adhesion and intensify the possibility of implant failure in patients with and without a previous history of periodontal disease. Surface topography and roughness are some of the aspects that can be easily manipulated by resorting to post-production surface treatments and that play an important role in the determination of cellular response, influencing adhesion, adsorption and differentiation

    Surgical combined approach for alveolar ridge augmentation with titanium mesh and rhPDGF-BB: A 3-year clinical case series

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    The purpose of this case series was to report the clinical outcomes and histologic findings of vertical ridge augmentation using a combination of titanium mesh and recombinant human platelet-derived growth factor BB (rhPDGF-BB). Two patients were included, and anorganic bovine bone particles were used. The bone graft was mixed with rhPDGF-BB and loaded onto the bony defect up to the level of the adjacent alveolar crest. A preadapted titanium mesh was placed over the grafted region; no areas of the grafted region were exposed. Postoperative healing was without complications. During reentry surgery for removal of the titanium mesh, all implants could be placed according to the prosthetic design. This report demonstrates the remarkable efficacy of guided bone regeneration using a combination of titanium mesh and rhPDGF for vertical ridge augmentation, thus expanding the indications for implant therapy and allowing recovery of the three-dimensional esthetic architecture in a severely resorbed alveolar ridge

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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