3,965 research outputs found
An antiviral substance from penicillium cyaneo-fulvum (in vivo studies)
No full textA strain of Penicillium cyaneo-fulvum, isolated in the Department of Bacteriology and Immunology, McGill University by Dr. G. D. Denton in 1947, * was found to produce a toxin neutralizing substance, Noxiversin (Diena, 1954, 1956; Tanner, 1956, 1957; Murray et al., 1958), as well as a separate and distinct antiviral substance (Cooke, 1958, 1960; Cooke and Stevenson, 1965 a, b). The antiviral agent, in both its crude and partially purified forms, was found to reduce the infectivity of influenza virus in embryonated eggs, modified Maitland cultures, monkey kidney cell cultures, and mice (Diena, 1956; Cooke, 1958, 1960; Syeklocha, 1962, 1964; Cooke and Stevenson, 1965b; David-West, 1966)
Targeting season and age for optimizing control of invasive rabbits
No full textAbstract not availableKonstans Wells, Phillip Cassey, Ron G. Sinclair, Greg J. Mutze, David E. Peacock, Robert C. Lacy, Brian D. Cooke, Robert B. O’Hara, Barry W. Brook, Damien A. Fordha
Tele-operated climbing and mobile service robots for remote inspection and maintenance in nuclear industry
No full textLa industria lítica de Gran Coclé, Panamá, a finales del periodo Cerámico medio. Resultado del análisis de material lítico de la Operación 8 de Sitio Cerro Juan Díaz
No full textBird, J. y R.G. Cooke
1978. “La Cueva de los Ladrones, datos
preliminares sobre la ocupacion formativa”, Actas
del V Simposium Nacional de Antropología Arqueología
y Etnohistoria de Panamá, Panamá, Universidad
de Panamá/Instituto Nacional de Cultura,
pp. 283-305.Bush, M.B. y P.A. Colinvaux
1990. “A pollen record of a complete glacial cycle
from lowland Panama”, Journal of Vegetation Science
1, pp. 105-18.Bush, M. B., D.R. Piperno, P.A. Colinvaux, P.A. P.E. de
Oliveira, L.A. Krissek, M.C. Miller y W.E. Rowe
1992. “A 14,300-yr. paleoecological profile of a
lowland tropical lake in Panama”, Ecological
Monographs, 62, pp. 251-275.Carbonell, E., M. Gilbaud y R. Mora
1982. “Aplicación de la methode dialectique à la
construction d’un systeme analytique pour
l’étude des matériaux du Paléolitique Inférieur”,
Dialektike, 7, pp. 23.Clary, James, P. Hansell, A.J. Ranere, T. Buggey
1984. “The Holocene geology of the western Parita
Bay coastline of central Panama”, en F.W. Lange
(ed.), Recent Developments in Isthmian Archaeology.
British Archaeological Reports, International Series
212, Oxford: B.A.R., pp. 55-83.Cooke, R.G.
1992. “Prehistoric Nearshore and Littoral Fishing
in the Eastern Tropical Pacific: An Ichthyological
Evaluation”, Journal of World Prehistory, 6, p. 1.1998. “Subsistencia y economía casera de los
indígenas precolombinos de Panamá”, en A. Pastor
(coord.), Antropología Panameña: Pueblos y Culturas,
Panamá, Universitaria, pp. 61-134.1999. “The Native People of Central America
during Precolumbian and Colonial Times”, en
Anthony Coates (coord.), Central America, a natural
and cultural history, New Haven y London, Yale
University Press, pp. 137-176.En prensa. “Prehistory of Native Americans on the
Central American Land Bridge: colonization,
dispersal and divergence”.Cooke, G. R. y A. Ranere
1984. “The ‘Proyecto Santa Maria’: a
multidisciplinary analysis of prehistoric
adaptations to a Tropical watershed in Panama”,
en F. Lange (coord.), Recent Developments in Isthmian
Archaeology, Oxford, British Archaeological Reports
International (Series 212), pp. 3-30.1992. “The origin of wealth and hierarchy in the
Central Region of Panama (12,000-2,000BP), with
observations on its relevance to the history and
phylogeny of Chibchan-speaking polities in
Panama and elsewhere”, en F. Lange (coord.),
Wealth and Hierarchy in the Intermediate Area,
Washington, DC, Dumbarton Oaks,
pp. 243-316.1994. “Relación entre recursos pesqueros, geografía
y estrategia de subsistencia en dos sitios
arqueológicos de diferentes edades en un estuario
del pacífico central de Panamá”, Memoria del
Primer Congreso Nacional del Patrimonio
Cultural, Panamá.Cooke, R.G., M. Jiménez, A. Ranere
2002. “Influencias humanas sobre la vegetación y
fauna de vertebrados de Panamá: actualización de
datos arqueozoológicos y su relación con el paisaje
antrópico”, en E. Leigh (coord.), Ecología y
Conservación en Panamá, Panamá, Smithsonian
Tropical Research Institute.Dillehay, T.D.
1989. Monte Verde: A Late Pleistocene Settlement in
Chile, vol. 1, Washington, D.C., Smithsonian
Institution Press.1997. Monte Verde: A Late Pleistocene Settlement in
Chile, vol. 2, Washington, D.C., Smithsonian
Institution Press.Hansell, Patricia
1988. “The Rise and Fall of an Early Formative
Community: La Mula-Sarigua, central Pacific
Panama”, tesis doctoral, Filadelfia, Universidad
de Temple Press.Iltis, H.H.
2000. “Homeotic sexual translocations and the
origin of maize (Zea mays, Poaceae): a new
look at an old problem”, Economic Botany, 54,
pp. 7-42.Jiménez, Máximo
1999. “Explotación de vertebrados acuáticos y
terrestres por los indígenas precolombinos en
Cerro Juan Díaz, Los Santos, durante el Periodo
300-700 d.C.”, tesis de graduación, Escuela de
Biología, Universidad de Panamá, Panamá.Jiménez, M. y R.G. Cooke
2001. “Pesca Precolombina en el Borde de un
Estuario Neotropical: Cerro Juan Díaz (Bahía de
Parita, Costa del Pacífico de Panamá)”, Actas del
39 Congreso de Americanistas, Quito, 1997.Laplace, G.
1974. “De la dynamique de l’Analyse structurale ou
la typologie analythique”, Di Science Prehistoriche,
XXIX, pp. 1-71.Leroi-Gourhan
1988. El hombre y la materia, Madrid, Taurus,
Comunicación.Linné, S.
1929. Darién in the past. The archaeology of eastern
Panama and north-westrn Colombia, Goterborgs
Kungl. Vetensakps och Vitterhets-Samhalles
Handillingar, Femte Foldjen. Goteborg, Elanders
Boktryckeri Aktiebolag (Ser. A. Band 3).Mayo Torné, J.
2004. “La Industria Prehispánica de Conchas
Marinas en Gran Coclé, Panamá”, tesis doctoral,
Departamento de Historia de América II
(Antropología americana), Universidad
Complutense de Madrid.McGimsey III, Ch. R.
1956. “Cerro Mangote. A preceramic site in
Panamá”, American Antiquity, vol. 22, pp. 151-161.McGimsey III, Ch. R., M.B. Collins y T.W. Mckern
1986-1987. “Cerro Mangote and its population”,
Journal of the Steward Anthropological Society, 16 (1 y
2), pp. 125-157.Merino, J. M.
1994. Tipología Lítica, Antropologia-Arkeologia.
Sociedad de Ciencias Aranzadi Zientzi Elkartea,
Suplemento 9, Munibe.Pearson, G.A.
2002. “Pan-Continental Paleoindian Expansions
and Interactions As Viewed from The Earliest
Lithic Industries of Lower Central America”, tesis
doctoral, Departamento de Antropología,
University of Kansas, mecanografiado.Pearson, G.A. y R.G. Cooke
2002. “The Role of the Panamanian Land Bridge
During the Initial Colonization of the Americas”,
Antiquity, 76, pp. 931-932.Piperno, D.R.
1989. “Non-affluent foragers: resource avaliability,
seasonal shortages and the emergence of
agriculture in Panamanian tropical forests”, en
D.R. Harris y G. Hillmanm (coords.), Foraging and
Farming: the Evolution of Plant Domestication,
Londres, Unwin Hymanç, pp. 538-554.1998. “Paleoethnobotany in the Neotropics from
microfossils: new insights into ancient plant use
and agricultural origins in the tropical forest”,
Journal of World Prehistory, 12, pp. 393-449.Piperno, D.R. y D.M. Pearsall
1998. The Origins of Agriculture in the Lowland Tropics,
San Diego, Academic Press.Piperno D.R., M.B. Bush y P.A. Colinvaux
1991. “Paleoecological perspectives on human
adaptation in Panama”, The Pleistocene
Geoarchaeology, 6, pp. 201-26.Piperno, D.R., A.J. Ranere, I. Holst y P. Hansell
2000. “Starch grains reveal early root crop
horticulture in the Panamanian tropical forest”,
Nature, 407, pp. 894-897.Piperno, D.R. y J.G. Jones
2003. “Paleoecological and archaeological
implications of a Late Pleistocene/early Holocene
record of vegetation and colimate chage from the
pacific coastal plain of Panama”, Quaternary
Research, 59, pp. 79-86.Ranere, A.
1973. “Una reinterpretación del precerámico
panameño”, Actas del III Simposium de
Antropología, Arqueología y etnohistoria de
Panamá, Panamá.Ranere, A. y R.G. Cooke
1995. “Evidencias de ocupación humana en
Panamá a postrimerías del Pleistoceno y a
comienzos del Holoceno”, en Cavelier y S. Mora
(eds.), Ámbito y Ocupaciones Tempranas de la América
Tropical, Bogotá, Fundación Erigaie/Instituto
Colombiano de Antropología, pp. 5-26.1996. “Stone Tools and Cultural Boundaries in
Prehistoric Panama”, en F. Lange (ed.), Paths to
Central American Prehistory, Niwot CO, University
Press of Colorado, pp. 49-77.2002. “Late glacial and early Holocene occupation
of Central American tropical forests”, en Julio
Mercader (ed.), Under the Canopy, New Brunswick,
Rutgers University Press, pp. 219-248.Sheets, Payson D., E.J. Rosenthal y A.J. Ranere
1980. “Stone tools from Volcan Barú”, en Linares y
Ranere (eds.), Adaptive Radiations in Prehistoric
Panama, Peabody Museum Monographs 5,
Cambridge, Harvard University Press,
pp. 404-428.Valerio Lobo, W.V.
1987. “Análisis estratigráfico y funcional de
Carabalí (SF-9). Un abrigo rocoso en la Regió
Writing Toward and With: Ethological Poetics and Nonhuman Lives
No full textIn this essay, the author argues that the appreciation of nonhuman poetic forms, or an “ethological poetics,” is a necessary but neglected mode of ecological relation, and is especially important in the Anthropocene. Motivated by his own creative practice—in particular, the composition of LYRE, a book of poems about different animals, plants, and landforms—he considers important examples of ethologically attentive poetics before outlining how his compositional method attempts to incorporate insights from the environmental humanities and animal studies. Rather than insisting on their essential difference from human worlds, the author argues for an attentive, ethical, and imaginative engagement with nonhuman lives, through which surprising and unusual forms of poetry might emerge.Full Tex
Structural, item, and test generalizability of the psychopathology checklist - revised to offenders with intellectual disabilities
No full textThe Psychopathy Checklist–Revised (PCL-R) is the most widely used measure of psychopathy in forensic clinical practice, but the generalizability of the measure to offenders with intellectual disabilities (ID) has not been clearly established. This study examined the structural equivalence and scalar equivalence of the PCL-R in a sample of 185 male offenders with ID in forensic mental health settings, as compared with a sample of 1,212 male prisoners without ID. Three models of the PCL-R’s factor structure were evaluated with confirmatory factor analysis. The 3-factor hierarchical model of psychopathy was found to be a good fit to the ID PCL-R data, whereas neither the 4-factor model nor the traditional 2-factor model fitted. There were no cross-group differences in the factor structure, providing evidence of structural equivalence. However, item response theory analyses indicated metric differences in the ratings of psychopathy symptoms between the ID group and the comparison prisoner group. This finding has potential implications for the interpretation of PCL-R scores obtained with people with ID in forensic psychiatric settings
Nitric oxide inhibition as a mechanism for blood pressure increase during salt loading in normotensive postmenopausal women
No full textObjectives: Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO), which plays an important role in natriuresis. We determined whether changes in endothelium-dependent vasodilation (EDD) and plasma ADMA predict changes in blood pressure (BP) after salt loading in normotensive postmenopausal women (PMW). Methods: In 15 normotensive PMW (age 50-60 years), not receiving estrogen, ambulatory 24-h BP, plasma lipids, and ADMA were measured after 4 days of a low-salt diet (70 mEq/day) and following 7 days of high-salt intake (260 mEq/day). Brachial artery diameter at rest, during reactive hyperemia, i.e. EDD, and after sublingual nitroglycerin, i.e. non-EDD, were measured by ultrasound. The 24-h urinary NO metabolite (NOx) was measured by Griess reaction. Plasma ADMA was measured by high-pressure liquid chromatography. Results: During low-salt, 24-h BP levels averaged 121 ± 11 and 69 ± 7 mmHg for systolic BP (SBP) and diastolic BP (DBP), respectively. After salt loading, average 24-h BP increases were: 7.6 mmHg for SBP, 2.2 mmHg for DBP, and 5.5 mmHg for pulse pressure (PP). Increases of 24-h SBP and 24-h PP after salt loading correlated directly with changes in ADMA (partial R2 = 0.16 for 24-h SBP and 0.17 for 24-h PP, P < 0.05 for both) and inversely with changes in EDD (partial R2 = 0.13, P = 0.09 for 24 h SBP and partial R2 = 0.15, P = 0.07 for 24-h PP), after adjustment for age and cholesterol. Conclusions: Inhibition of NO bioavailability by ADMA and a subsequent reduction in EDD contribute to the increase in BP during high-salt intake in normotensive PMW not receiving estrogen
Transversality and Transition: Branching to New Regional Path Dependence
No full textSince Paul David published his economic histories of path dependent innovation the subject has exerted fascination upon scholars of innovation, technological change and, latterly, regional scientists and economic geographers. This paper speaks to the third and fourth of these communities in the main, though it may have theoretical and empirical elements of interest to the first two as well. The paper begins with an overview of recent perspectives and critiques concerning the relevance of the path dependence concept to the understanding of regional economic development and its associated governance. It then goes on to discuss the contribution of evolutionary economic geography to thinking about ÔbranchingÕ from path dependence and the creation of new paths. Evidence for key generic spatial processes of path transition is provided before the main content of the paper concludes with new insights into the contributions of regional innovation policy to path evolution. Conclusions are then drawn.regional path dependence, branching, transition, transversality
Characterization and structure in the development of Tudor comedy
No full textThe role of characterization in dramatic structure is assessed by theoretical criteria.
Characters who perform actions necessary for the completion of the narrative sequence are
said to be "bound" to the narrative; those without such obligations are "free". Characters
who maintain a single, constant meaning during the course of a play are said to be "static";
characters who change or develop into new roles are "dynamic". Horatian decorum
demanded that comic characters be static, and the characters of Plautine and Terentian
tradition were almost always bound to narrative intrigue. However, evaluations of six
Tudor comedies show an increasing use of non-classical characterization within the comic
form.
In the early comedies lohan lohan and Roister Doister all characters are bound and
static, yet the impetus to enlarge the role of characterization is evident. The characters of
lohan lohan are expanded from their French source, and Roister Doister includes
extraneous episodes in which Udall displays his braggart hero. Free characters abound in
Misogonus; as well the play brings dynamic characterization into the scope of comedy with
the conversion of its prodigal son.
Free characters offer new possibilities of non-narrative plotting. In comedies of the
1580s favourite traditional characters appear as diversions outside the action, and thematic
arrangements of characters inform the increasingly complex plots. Lyly stresses the
symbolic potential of characters in Endimion, whereas Greene uses dynamic
characterization to heighten the illusion of independent figures in Friar Bacon and Friar
Bungay. Love's Labour's Lost exposes the limitations of comic artifice by pulling the
characters between convention and individualization.
By the end of the sixteenth century free and dynamic characters had become
common, and characterization had established a sizable claim on the design of English
comedy. These developments set the English form apart from its neoclassical counterparts
A new HPLC-ELSD method to quantify indican in Polygonum tinctorium L. and to evaluate beta-glucosidase hydrolysis of indican for indigo production
No full textA method to quantify the indigo precursor indican (indoxyl-beta-D-glucoside) in Polygonum tinctorium L. has been developed. Plant material was extracted in deionized water, and indican was identified and quantified using high performance liquid chromatography (HPLC) coupled to an evaporative light scattering detector (ELSD). Results confirmed that with this method it is possible to measure indican content in a short time, obtaining reliable and reproducible data. Using this method, leaf indican content was quantified every 15 days during the growing season (from May to October) in P. tinctorium crops grown in a field experiment in Central Italy. Results showed that indican increased along the growing season until flowering and was positively affected by photosynthetic active radiation (PAR). Indican is naturally hydrolyzed by native beta-glucosidase to indoxyl and glucose, the indoxyl yielding indigo. The activity of two enzymes, sweet almond beta-glucosidase and Novarom G preparation, were compared with P. tinctorium native beta-glucosidase to evaluate indigo production. Results showed that the ability to promote indigo formation increased as follows: almond beta-glucosidas
- …
