728 research outputs found

    Code for a microRNA Conservation Bioinformatics Collaboration Between the Van Vactor Lab and Wall Lab

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    <p>This code repository is a part of the the microRNA conservation bioinformatics collaboration between the Van Vactor Lab and Wall Lab, including Elizabeth M. McNeill, Todd F. DeLuca, Dennis P. Wall, and David Van Vactor.</p&gt

    Older and Happier? Associations Among Age, Affective Symptomatology, and Quality of Life in Persons With Multiple Sclerosis

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    Abstract Date Presented 3/31/2017 This study identifies a relationship between age and quality of life in persons with multiple sclerosis. It highlights the role of promoting coping in younger adults to prevent or decrease symptoms of depression or anxiety as a means of increasing quality of life. Primary Author and Speaker: Brocha Stern Contributing Authors: John DeLuca, Yael Goverover</jats:p

    Oral History Interview, David Musolf (1078)

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    In David Musolf's nine interview sessions, he sheds light on his long-term involvement with UW Madison. He first discusses his early interest in the natural world and how influential family has been through the course of his life. We recommend downloading and reading the index to learn more. By reviewing the index, you can download specific audio files as well.In his nine interviews with Bob Lange, David Musolf details his long involve-ment with the University of Wisconsin and restoration ecology from the 1950s to 2010, when the interview was conducted. He began by recounting his early interest in the natural world, living close to the shores of Lake Mendota, and continued by discussing the influential role of family, the UW, Peace Corps, in forming his professional and personal skills. Following a discussion of his years working for MACC and IES, he spent significant time discussing his work as Secretary of the Faculty, especially his role on the University Committee, its chairs and significant issues it had faced over his two-decade involvement with it. Toward the end of the interview, he also chronicled his long involvement with prairie and wetland restoration in Lake Mills WI with the Madison Audubon Society and his partner, Roger Packard. Throughout, Musolf offered his opinions and perspectives on significant UW figures such as Donna Shalala, John Wiley, and Biddy Martin; University Committee chairs and members; faculty policies and procedures; shared governance; a recent restructuring proposal by Provost DeLuca; and his role in commencement ceremonies. This interview was conducted for inclusion into the UW-Madison Oral History Program

    Therapy Dogs Assisting Those With Autism

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    Design of a study to examine the effects of therapy dogs on children and adults diagnosed with autism.Fall 2012Accompanied by video fil

    From the Margins to the Forefront: Tillie Olsen\u27s Mediation as Figure and Author

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    Tillie Olsen\u27s life experiences and self-identification as a working class woman provide a strong basis for analyzing her fiction as partly autobiographical. As she wrote, she developed her position as a recognized and award winning author into that of a literary mediator for socially marginalized subjects, actively working to represent certain conditions of exclusion due to social, racial, economic, and sexual factors during the 1970\u27s and 1980\u27s. Through analysis of her fiction and non-fiction texts, her use of modernist writing techniques, her purpose as a writer, and her impact on the literary canon, it becomes possible to see how she has altered the literary landscape and has made those who suffer exclusion visible and legible. | 45 page

    From the Margins to the Forefront: Tillie Olsen's Mediation as Figure and Author

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    45 pg.Tillie Olsen's life experiences and self-identification as a working class woman provide a strong basis for analyzing her fiction as partly autobiographical. As she wrote, she developed her position as a recognized and award winning author into that of a literary mediator for socially marginalized subjects, actively working to represent certain conditions of exclusion due to social, racial, economic, and sexual factors during the 1970's and 1980's. Through analysis of her fiction and non-fiction texts, her use of modernist writing techniques, her purpose as a writer, and her impact on the literary canon, it becomes possible to see how she has altered the literary landscape and has made those who suffer exclusion visible and legible.Advisor(s): Choi, Helen . Committee Member(s): Marshik, Celia.Stony Brook University Libraries. SBU Graduate School in Department of English. Charles Taber (Dean of Graduate School)

    Caratterizzazione fisiografica, geomorfologica e bionomica dellaRiasdi Santa Teresa di Gallura: Sardegna nord-orientale = Physiographic, geomorphological and bionomic characterization of the Santa Teresa di GalluraRias(N.E. Sardinia)

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    An underwater survey in theRiasof S. Teresa di Gallura was made to characterize the benthic environment by integrating three methods: Side Scan Sonar, ROV, SCUBA diving. The main bionomic features at different depths were described and mapped. The presence ofSavalia savaglia, a rare Mediterranean species contributed to enhance the environmental value of the study area

    Does biochar application alter heavy metal dynamics in agricultural soil?

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    Biochar incorporation into soil has been advocated as a potential large scale solution to offset global greenhouse gas emissions. However, the application of biochar to agricultural land must have few if any negative economic and environmental consequences if farmers are to readily adopt biochar as soil amendment. Biochar use as an organic amendment has been recently rising due to its positive effect on soil fertility, but there is still limited information available about longer-term effects, especially with regard to the effects on soil pollutant content and distribution. In a field-scale trial we investigated the effect of single doses of biochar (25 and 50 t ha-1) and repeat-applications (two years later) of biochar (25 + 25 and 50 + 50 t ha-1) on heavy metal (As, Cu, Zn, Cd, Ni) content and distribution in soil, together with metal concentrations in plants (barley, beans) over repeated cropping cycles. Here we demonstrate that biochar produced from forest residues is of a low risk due to its inherently low metal content and the lack of observed negative effects on crop or soil quality. Although biochar did cause small changes in metal fractionation in soil, it did not alter total metal concentrations in soil or plants. We conclude that the application of wood-derived biochar does not increase the concentrations of metals in this soil, even after repeated applications, and could be safely used for agriculture

    Development of a peptide-containing chewing gum as a sustained release antiplaque antimicrobial delivery system

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    The objective of this study was to characterize the stability of KSL-W, an antimicrobial decapeptide shown to inhibit the growth of oral bacterial strains associated with caries development and plaque formation, and its potential as an antiplaque agent in a chewing gum formulation. KSL-W formulations with or without the commercial antibacterial agent cetylpyridinium chloride (CPC) were prepared. The release of KSL-W from the gums was assessed in vitro using a chewing gum apparatus and in vivo by a chew-out method. A reverse-phase high-performance liquid chromatography method was developed for assaying KSL-W. Raw material stability and temperature and pH effects on the stability of KSL-W solutions and interactions of KSL-W with tooth-like material, hydroxyapatite discs, were investigated. KSL-W was most stable in acidic aqueous solutions and underwent rapid hydrolysis in base. It was stable to enzymatic degradation in human saliva for 1 hour but was degraded by pancreatic serine proteases. KSL-W readily adsorbed to hydroxyapatite, suggesting that it will also adsorb to the teeth when delivered to the oral cavity. The inclusion of CPC caused a large increase in the rate and extent of KSL-W released from the gums. The gum formulations displayed promising in vitro/in vivo release profiles, wherein as much as 90% of the KSL-W was released in a sustained manner within 30 minutes in vivo. These results suggest that KSL-W possesses the stability, adsorption, and release characteristics necessary for local delivery to the oral cavity in a chewing gum formulation, thereby serving as a novel antiplaque agen
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