282 research outputs found

    David A. Caughey and Francis C. Moon discuss the history of the Sibley School and Fluid Mechanics

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    This video is an oral history interview of David Caughey by Frank Moon on April 18, 2014.1_jg5q9j7

    ROTATIONAL RELAXATION WITHIN S2(B3Σu,v=4)S_{2} (B^{3}\Sigma^{-}_{u}, v''=4)

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    1^{1}T. A. Caughey and D. R. Crosley, J. Chem. Phys. 69, 3379 (1978).Author Institution:Rates for collision-induced transfer from a single rotational level (N=40,J=41N^{\prime\prime}=40, J^{\prime\prime}=41) to other individual rotational levels within the v=4v^{\prime\prime}=4 vibrational level of the B3ΣuB^{3}\Sigma^{-}_{u} state of S2S_{2} are reported. The S2S_{2} was excited by atomic Zn line radiation, and rotationally resolved fluorescence measurements were used to determine the rates for the collision partners He, Ar and Xe. Single collision multiquantum transfer is found, but (for F1F1F_{1} \rightarrow F_{1} transfer) with a magnitude which decreases with ΔN|\Delta N|. For small ΔN,F1F1\Delta N, F_{1} \rightarrow F_{1} transfer is preferred over F1F3,F2F_{1} \rightarrow F_{3}, F_{2}. A surprisal plot for F1F1F_{1} \rightarrow F_{1} transfer is linear for ΔN4|\Delta N|\geq 4 with the following slopes: He, 4.6; Ar, 3.4; Xe: 1.9. These results and those for vibrational and total rotational relaxation1relaxation^{1} indicate a brief collision encounter

    Polyandric acid A, a clerodane diterpenoid from the Australian medicinal plant Dodonaea polyandra, attenuates pro-inflammatory cytokine secretion in vitro and in vivo

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    Published: January 8, 2014Dodonaea polyandra is a medicinal plant used traditionally by the Kuuku I'yu (Northern Kaanju) indigenous people of Cape York Peninsula, Australia. The most potent of the diterpenoids previously identified from this plant, polyandric acid A (1), has been examined for inhibition of pro-inflammatory cytokine production and other inflammatory mediators using well-established acute and chronic mouse ear edema models and in vitro cellular models. Topical application of 1 significantly inhibited interleukin-1β production in mouse ear tissue in an acute model. In a chronic skin inflammation model, a marked reduction in ear thickness, associated with significant reduction in myeloperoxidase accumulation, was observed. Treatment of primary neonatal human keratinocytes with 1 followed by activation with phorbol ester/ionomycin showed a significant reduction in IL-6 secretion. The present study provides evidence that the anti-inflammatory properties of 1 are due to inhibition of pro-inflammatory cytokines associated with skin inflammation and may be useful in applications for skin inflammatory conditions including psoriasis and dermatitis.Bradley S. Simpson, Xianling Luo, Maurizio Costabile, Gillian E. Caughey, Jiping Wang, David J. Claudie, Ross A. McKinnon, and Susan J. Sempl

    A Numerical Investigation Of Turbulence-Driven And Forced Generation Of Internal Gravitywaves In Stratified Mid-Water

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    Natural and externally-forced excitation of internal gravity waves in a uniformly stratified fluid have been thoroughly investigated by means of highly resolved large eddy simulations. The first part of the thesis focuses on the generation of high frequency internal gravity waves by the turbulent wake of a towed sphere in a uniformly stratified fluid. We have used continuous wavelet transforms to quantify relevant wavelength and frequencies and their spatial and temporal dependence in the near field of the wake. The dependence on Reynolds number and Froude number of the internal wave field wavelengths, frequencies and isopycnal displacements are reported for the first time. The initial wavelengths and decay rates show a dependence on both parameters that can not be explained on the basis of impulsive mass source models. The results also clearly identify Reynolds number as the main driver for the observed selection of a narrow range of wave phase- line-tilt-angles and shed some light on the coupling of the waves and turbulent wake region at high Reynolds number. Finally, the potential for nonlinear interactions, instability and breaking of the waves increases with both Reynolds and Froude numbers. The results of this part of the thesis motivate future theoretical investigations into the underlying generation mechanisms and improved parametrization of the role of small scale processes, such as high frequency internal gravity waves, in large scale circulation models in the ocean and atmosphere. In the second half of the thesis, we have focused on the generation of an internal gravity wavepacket by a vertically localized transient forcing. We have found that the unique combination of strong vertical localization and large wave amplitude, typically not considered in the literature, lead to the formation of strong horizontal mean flow inside the wave forcing region that nonlinearly grows at the expense of a depleted and structurally modified emerging internal wave packet. A novel theoretical analysis is developed which can explain the underlying mechanism for the formation of the mean flow. By appealing to scaling arguments, based on a one way wave-mean flow interaction, we quantify the mean flow dependence on the input parameters. By means of a phase averaging procedure, we offer additional insight on mean flow reduction through horizontal localization of a wavepacket. Finally, mean flow containment techniques that allow the generation of a well-defined wavepacket that preserves its structure near the source and during the propagation towards a remote interaction region are proposed and tested. The efficiency of the techniques is tested in a simulation of internal gravity wave-shear flow interaction near a critical level. The simulations qualitatively agree with previous numerical investigations of such flow

    Convergence Acceleration

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    President Hushang Bahar Interviews, 1986

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    Transcript of a series of 1986 interviews with the College's first President, Hushang Bahar. Interview condensed by Nancy Craft from the original video interviews. Interview #1 transcribed by Patty Caughey; #2 and #3 by Darlene Finn; and #4 by Lisa Doran.Archived web conten

    Computational Fluid Dynamics

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