76 research outputs found
Dinner hosted by Secretary Schultz in honor of Dean Rusk
No full textDinner in honor of David Dean Rusk and Virginia Rush in celebration of David Rusk's 75th birthday. George P. Shultz hosted of the event. C. Douglas Dillon and Benjamin Read saluted the honorees and remarked on David's career over the years. Mrs. Lyndon Johnson gave a salute, and made remarks about Dean and Virginia, and their friendship of 25 years, and Dean's service to her, President Lyndon Johnson, and his country
Potlatch Elementary School Mrs. Stella Benjamin's 6th grade class
No full textFront row, Terry Kirtcher, Larry Griffin, Jim Spangler, James Merrit, David Morrison, Gary Hansen, Dannie Raupe. 2nd row, Ed Mitzenberg, Ron Owens, Sharon Vandermark, Sally Pelton, Marvin Wilkerson, Beatrice Swanson, Patty Stockwell. 3rd row, Arlene Coleman, Marlene Merril, Joe Rohn, Sharon Mundy, Sharon Shultz, Jim Spelgatti, Don Nygaard, Teacher Stella Benjamin. 6th grade
Potlatch Elementary School Mrs. Stella Benjamin's 6th grade class
No full textFront row, Terry Kirtcher, Larry Griffin, Jim Spangler, James Merrit, David Morrison, Gary Hansen, Dannie Raupe. 2nd row, Ed Mitzenberg, Ron Owens, Sharon Vandermark, Sally Pelton, Marvin Wilkerson, Beatrice Swanson, Patty Stockwell. 3rd row, Arlene Coleman, Marlene Merril, Joe Rohn, Sharon Mundy, Sharon Shultz, Jim Spelgatti, Don Nygaard, Teacher Stella Benjamin. 6th grade
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Measuring Merit: The Shultz-Zedeck Research on Law School Admissions
No full textLaw schools profess a commitment to racial diversity both for the educational benefits diversity confers and for its contribution to the profession. But they admit students based on standards and practices that, while not discriminatory in a legal sense, undeniably favor white applicants. In practice, the Law School Admissions Test (LSAT) drives admissions decisions more than any other factor, despite the fact that it disproportionately disadvantages (and excludes) applicants of color. If it is true that racial diversity is crucial to quality legal education and to an effective legal profession-and we believe it is-then the right thing to do is to consider whether our current admissions practices can be changed for the better. This essay describes research that explored that question.</p
Continued versus interrupted targeted therapy during metastasis-directed stereotactic radiotherapy: a retrospective multi-center safety and efficacy analysis
No full textThe increasing use of targeted therapy (TT) has resulted in prolonged disease control and survival in many metastatic cancers. In parallel, stereotactic radiotherapy (SRT) is increasingly performed in patients receiving TT to obtain a durable control of resistant metastases, and thereby to prolong the time to disseminated disease progression and switch of systemic therapy. The aims of this study were to analyze the safety and efficacy of SRT combined with TT in metastatic cancer patients and to assess the influence of continuous vs. interrupted TT during metastasis-directed SRT. The data of 454 SRTs in 158 patients from the international multicenter database (TOaSTT) on metastatic cancer patients treated with SRT and concurrent TT (within 30 days) were analyzed using Kaplan-Meier and log rank testing. Toxicity was defined by the CTCAE v4.03 criteria. The median FU was 19.9 mo (range 1-102 mo); 1y OS, PFS and LC were 59%, 24% and 84%, respectively. Median TTS was 25.5 mo (95% CI 11-40). TT was started before SRT in 77% of patients. TT was interrupted during SRT in 44% of patients, with a median interruption of 7 (range 1-42) days. There was no significant difference in OS or PFS whether TT was temporarily interrupted during SRT or not. Any-grade acute and late SRT-related toxicity occurred in 63 (40%) and 52 (33%) patients, respectively. The highest toxicity rates were observed for the combination of SRT and EGFRi or BRAF/MEKi, and any-grade toxicity was significantly increased when EGFRi (p = 0.016) or BRAF/MEKi (p = 0.009) were continued during SRT. Severe (≥grade 3) acute and late SRT-related toxicity were observed in 5 (3%) and 7 (4%) patients, respectively, most frequently in patients treated with EGFRi or BRAF/MEKi and in the intracranial cohort. There was no significant difference in severe toxicity whether TT was interrupted before and after SRT or not. In conclusion, SRT and continuous vs. interrupted TT in metastatic cancer patients did not influence OS or PFS. Overall, severe toxicity of combined treatment was rare; a potentially increased toxicity after SRT and continuous treatment with EGFR inhibitors or BRAF(±MEK) inhibitors requires further evaluation
Nonparametric Motion Control in Functional Connectivity Studies in Children with Autism Spectrum Disorder
No full textAutism Spectrum Disorder (ASD) is a neurodevelopmental condition associated with difficulties with social interactions, communication, and restricted or repetitive behaviors. To characterize ASD, investigators often use functional connectivity derived from resting-state functional magnetic resonance imaging of the brain. However, participants\u27 head motion during the scanning session can induce motion artifacts. Many studies remove scans with excessive motion, which can lead to drastic reductions in sample size and introduce selection bias. To avoid such exclusions, we propose an estimand inspired by causal inference methods that quantifies the difference in average functional connectivity in autistic and non-ASD children while standardizing motion relative to the low motion distribution in scans that pass motion quality control. We introduce a nonparametric estimator for motion control, called MoCo, that uses all participants and flexibly models the impacts of motion and other relevant features using an ensemble of machine learning methods. We establish large-sample efficiency and multiple robustness of our proposed estimator. The framework is applied to estimate the difference in functional connectivity between 132 autistic and 245 non-ASD children, of which 34 and 126 pass motion quality control. MoCo appears to dramatically reduce motion artifacts relative to no participant removal, while more efficiently utilizing participant data and accounting for possible selection biases relative to the naïve approach with participant removal
Effects of altered precipitation and wolf spiders on the density and activity of forest-floor Collembola
No full textThe antecedents and consequences of service customer citizenship and badness behavior
No full textThis paper presents an empirical test of the antecedents and consequences of customer extra-role behavior (i.e., customer citizenship behavior and badness behavior). The model posits that negative affect, perceived justice, and commitment lead to customer extra-role behavior. In turn, such extra-role behavior is expected to impact perceived service quality. The model was tested in an exercise class context of participants at sports center. Results from the empirical test indicated that managing customer extra-role behavior is as important as that of employee. Secondly, the study found that the organization have to manage the negative affect of customers to prevent customer badness behavior, and perceived justice and commitment to increase customer citizenship behavior. Implications are discussed, possible areas of further research are indicated, and limitations of the study are noted
Milton Friedman and U.S. monetary history: 1961-2006
No full textThis paper, using extensive archival material from several countries, brings together scattered information about Milton Friedman's views and predictions regarding U.S. monetary policy developments after 1960 (i.e., the period beyond that covered by his and Anna Schwartz's Monetary History of the United States). The author evaluates these interpretations and predictions in light of subsequent events.Friedman, Milton ; Federal Reserve System - History ; Economic history
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