1,721,064 research outputs found
[The "problem obesity": viewpoint of the internist].
No full textThe prevalence of obesity has reached epidemic dimension in industrialized countries and it is known that obesity is associated with increased risk of cardiovascular morbidity and mortality. Commonly, obesity is defined by the Body Mass Index (BMI). However, BMI fails to consider body fat distribution. The relationship between the risk of metabolic-cardiovascular diseases and body fat distribution indices such as the waist-to-hip ratio (WHR) and the waist circumference, rather than measures of the degree of body fatness as expressed by BMI, has long been recognized. Recently, clinical and epidemiological research has found waist circumference to be the best anthropometric indicator of both total body fat and intra-abdominal fat mass. Android or visceral obesity is associated with metabolic syndrome and increased cardiovascular morbidity and mortality through a variety of molecular mechanisms possibly linking the metabolic syndrome to hemostatic and vascular abnormalities. Obesity guidelines suggest the need for weight reduction using behavioural change to reduce caloric intake and increasing physical activity. A realistic goal for weight reduction is to reduce body weight by 5% to 10% over a period of 6 to 12 months. Combined intervention of a low calories diet, increased physical activity, and behaviour therapy provides better outcomes for long-term weight reduction and weight maintenance than programs that use only one or two of these modalities. The drugs used to promote weight loss have been anorexic drugs or appetite suppressants. All classes of anorexic drugs affect neurotransmitters in the brain. The new agent sibutramine has norepinephrine and serotonin effects. Another new agent, orlistat, has a different mechanism of action, the reduction of fat absorption. Weight loss drugs approved by the FDA for long-term use may be useful as an adjunct to diet, physical activity and behaviour therapy for patients with a BMI of > or =30 with no concomitant obesity-related risk factors or diseases, and for patients with a BMI of > or =27 with concomitant obesity-related risk factors or disease
Complications of argon laser retinal buckling performed in myopic subjects presenting rhegmatogenous degenerations.
No full textOtticopatia ischemica anteriore bilaterale e progressiva da arterite di Horton nonostante copertura corticosteroidea intravenosa.
No full textTooth implant-supported removable denture: a systemaric review
No full textPurpose: The aim of this systematic review is to verify whether tooth-implant supported removable dentures (TISRD) can really be proposed to patients as a successful alternative to traditional prosthetic therapy.
Methods: This systematic review was carried out following the PRISMA guidelines and the studies were selected by PubMed and Scopus. The keywords were “tooth-implant connection,” “removable denture,” “removable dental prosthesis,” “tooth and implant supported removable dentures,” “partial dentures,” and “overdenture.” The outcomes sought in the potentially eligible studies were the survival rate of TISRD, the patient satisfaction, presence of biological and technical complications; furthermore the bias risk assessment was performed.
Results: Out of the 3108 citations found, 19 studies met the inclusion criteria. In the included studies the enrolled participants were 615, the implant abutments were 1118 and the residual teeth were 601. The behaviour of abutments was examined for a time range between 6 and 180 months. The survival rate of TISRD ranged between 91.82 and 100%; as for complications, none of the authors reported intrusion and the most frequent biologi.
Clinical significance: The tooth-implant connection seems to be an alternative and beneficial treatment for the rehabilitation of partially edentulous patients, however the evidence remains slight and unclear due to the shortage of controlled and randomized clinical trials. Therefore, further studies with a higher level of evidence and more representative samples are need
I rapporti vitreo retinici periferici nella diagnostica e patogenesi delle malattie retiniche.
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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