323,222 research outputs found
Letter from Enrico Davanzo to Santo Tiné
No full textHandwritten correspondence from Enrico Davanzo to Santo Tiné concerning the drawing of a floor plan for Grotta Scaloria
Epidemiological data on chemical poisoning of animals: a source for risk assessment
No full textChemicals, included in the category of pesticides (n.1159 cases), insecticides, rodenticides, molluscicides, herbicides and fungicides, and household products (n. 191 cases), are among the main classes involved in animal poisoning. Epidemiological studies were carried out from 2010 to 2013 based on the Human Poison Control Centre of Milan (Centro Antiveleni di Milano, CAV) data related to domestic animal poisoning, in collaboration with the Veterinary Toxicology Section of the University of Milan. Data, processed for epidemiological analysis and evaluated in terms of the animal species, toxic substance, clinical signs and final outcome, were classified and represent an interesting database of chemical exposure. Most of the suspected poisoning cases were related to anticholinesterase insecticides, carbamates (methomyl), organophosphates (chlorpyriphos), and pyrethrins-pyrethroids. Frequently reported cases involved rodenticides such as anticoagulants, zinc phosphide, chlorophacinone, α-chloralose together with the molluscicides metaldehyde and methiocarb, in cases involving pets. Occasionally, the herbicides paraquat and glyphosate and fungicides like copper sulphate, copper oxychloride, ziram were reported. Caustic agents like sodium hydroxide, a drain cleaner also known as caustic soda and detergents and other frequent household toxicants such as solvents (hydrocarbons) used in paints and domestic fuel, fertilizers and ethylene glycol, used as an anti-freeze, are culprits causing intoxication. Epidemiological data collected can be a useful source and a key tool for chemical risk assessment.
References:
Caloni F, Cortinovis C, Rivolta M, Davanzo F Animal poisoning in Italy: 10 years of epidemiological data from the Poison Control Centre of Milan, 2012, Veterinary record 170, 415
Caloni F Berny P, Croubels S, Sachana M,Guitart R Epidemiology of poisonings in Europe, 2012, Chapter 7 pp 88-97 Veterinary Toxicology, Editor R. Gupta,2nd Edition
Caloni F, Cortinovis C, Pizzo F, Rivolta M, Panzavolta G, Falciola C, Davanzo F Poisoning of domestic animals: 2011 data from poison control centre of Milan, 2012, Toxicology letters, 214, 211S
Caloni F, Cortinovis C, Pizzo F, Rivolta M, Davanzo F. Poisoning of domestic animals data from Poison Control Centre of Milan, 2012, Toxicology letters, 221, S25
Epidemiologia degli avvelenamenti da pesticidi negli animali domestici in Italia
No full textDati epidemiologici relativi alle intossicazioni negli animali domestici hanno dimostrato che i pesticidi rappresentano una delle classi di maggior frequenza seguita da farmaci, prodotti ad uso domestico, household, e piante (Caloni et al., 2012, Caloni et al., 2013; Caloni et al., 2014). Nel periodo compreso tra 1 gennaio 2012 e 31 dicembre 2013, il Centro Antiveleni di Milano (CAV) ha registrato 222 casi di intossicazione da pesticidi corrispondenti al 39% delle intossicazioni totali. Il cane è risultata la specie maggiormente esposta con l'85,1% di chiamate, seguita dal gatto (11,3%) e altre specie (3,6%). Nell'ambito dei pesticidi gli insetticidi hanno rappresentato il 42%, seguiti dai rodenticidi (26,1%), erbicidi (14,9%), molluschicidi (8,1%) e fungicidi (5,9%). Gli insetticidi maggiormente coinvolti sono risultati i piretroidi (35%) e organofosforati (11%). La frequenza di chiamate relative ai neonicotinoidi (10%), superiori ai carbamati (6%) e organoclorurati (2%), è indicativo di un elevato impiego in ambiente domestico di questi pesticidi. Nell'ambito dei rodenticidi, i composti più frequentemente responsabili di intossicazione sono stati i rodenticidi
anticoagulanti come bromadiolone e brodifacoum. Per quanto riguarda gli erbicidi, responsabili di un numero sempre più crescente di intossicazioni, sono stati riportati diversi casi di avvelenamento da glifosato (64% delle chiamate), un erbicida ad ampio spettro, largamente impiegato. La metaldeide, è risultata sempre il molluschicida per il quale sono state registrate il maggior numero di chiamate (50%) e per i fungicidi i composti del rame, a seguito di esposizione per via orale, hanno rappresentato il 77% delle intossicazioni. Queste informazioni, da una parte confermano i dati già riportati in altre indagini (Caloni et al., 2012), dall'altra rivelano un andamento di notevole interesse, riportando un aumento dell'esposizione degli animali domestici ad alcune sostanze
(neonicotinoidi, glifosato), rispetto ad altre (organoclorurati), fornendo indicazioni per la valutazione delle intossicazioni in ambito veterinario.
Bibliografia
- Caloni F, Cortinovis C, Pizzo F, Rivolta M, Davanzo F. Epidemiological study (2006-2012) on the poisoning of small
animals by human and veterinary drugs. Vet Rec. 2014 Mar 1;174(9):222. Pubmed PMID: 24477472.
- Caloni F, Cortinovis C, Rivolta M, Alonge S, Davanzo F. Plant poisoning in domestic animals: epidemiological data from
an Italian survey (2000-2011). Vet Rec. 2013 Jun 1;172(22):580. Pubmed PMID: 23716536.
- Caloni F, Cortinovis C, Rivolta M, Davanzo F. Animal poisoning in Italy: 10 years of epidemiological data from the
Poison Control Centre of Milan. Vet Rec. 2012 Apr 21;170(16):415. Pubmed PMID: 22271801
Cytomegalovirus, varicella-zoster virus, and epatiti c virus infections and breastfeeding: the states of the art
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Mammal skeletal remains from the Fumane cave (Verona, Northern Italy): an oxygen isotope study and its palaeoclimatological implications
No full textSpatial and temporal variations in the 13C/12C and 15N/14N ratios of mammoth hairs: Palaeodiet and palaeoclimatic implications.
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A CASE-CONTROL STUDY OF DIABETES-MELLITUS AND CANCER RISK
No full textThe relationship between diabetes mellitus and cancer risk was investigated using data from an integrated series of case-control studies conducted in Northern Italy between 1983 and 1992. Cases were 9,991 patients with incident, histologically confirmed neoplasms below age 75, including 181 cancers of the oral cavity and pharynx, 316 of the oesophagus, 723 of the stomach, 828 of the colon, 498 of the rectum, 320 of the liver, 58 of the gall bladder, 362 of the pancreas, 242 of the larynx, 3,415 of the breast, 726 of the endometrium, 971 of the ovary, 125 of the prostate, 431 of the bladder, 187 of the kidney, 208 of the thyroid, 80 Hodgkin's lymphomas, 200 non-Hodgkin's lymphomas and 120 multiple myelomas. Controls were 7,834 subjects in hospital For acute, non-neoplastic, non-metabolic, non-hormone-related disorders. A history of diabetes was reported by 5.1% of male and 5.4% of female controls. Significantly elevated relative risks (RRs) among subjects with diabetes were observed for cancers of the liver [RR = 2.8, 95% confidence interval (CI) 2.0-3.9], pancreas (RR=2.1, 95% CI 1.5-2.9) and endometrium (RR=3.4, 95% CI 2.7-4.3). After allowance for obesity and education as well as age and sex, the RRs were 3.0 for liver, 2.3 for pancreas, and 2.8 for endometrium. Diabetic subjects had no elevated risk for any of the other cancer sites considered. For liver and endometrial cancer the RRs remained elevated up to 10 years after diagnosis of diabetes (RR 2.6 and 2.0 respectively), while the RR for pancreatic cancer declined from 3.2 in the first 5 years after diagnosis of diabetes to 2.3 from 5 to 9 years and to 1.3 (95% CI 0.7-2.3) 10 or more years since diagnosis. This suggests that the relationship between diabetes mellitus and liver and endometrial cancer is probably real, while that with pancreatic cancer is compatible with diabetes being an early symptom of the disease, or at least of preneoplastic lesions
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