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    Comparative study of the hypoglycemic effects of coconut water extract of Picralima nitida seeds (Apocynaceae) and Daonil in alloxan-induced diabetic albino rats

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    The study was designed to compare the hypoglycemic effects of coconut water extract of Picralima nitida seeds to that of Daonil in alloxan-induced diabetic albino rats. Twenty five albino rats weighingbetween 170 - 200 g were randomly divided into five groups after allowing the rats to acclimatize for seven days and were made diabetic by intraperitoneal administration of 150 mg/kg of alloxan. The ratswere giving different volumes of the extract and Daonil as per their groupings. All the substances were given for five days by oro-gastric tube. The blood glucose level were measured daily in the rats. Therewas an initial inactivity in the rats following administration of the extract mixture and their appetite was low except for the control group. The blood glucose levels (in mmols/dL) of the rats at the start and endof the experiment for the groups were: control (9.6 ± 0.1 to 9.2 ± 0.1), coconut water only (11.5 ± 0.3 to 6.2 ± 0.1), aqueous extract of P. nitida seeds (12.4 ± 0.1 to 5.8 ± 0.2), coconut water extract of P. nitidaseeds (11.8 ± 0.2 to 4.2 ± 0.1), and Daonil (10.5 ± 0.4 to 4.3 ± 0.1). Therefore, coconut water extract of P. nitida seeds have a significant hypoglycemic effects in alloxan-induced diabetes comparable to that ofthe Daonil, hence, it could be an effective adjunct in the management of diabetes mellitus

    ‫الثالث-‬ ‫العدد‬ ‫التاسع-‬ ‫المجلد‬ ‫الطبية-‬ ‫بابل‬ ‫مجلة‬ Acetylcholinesterase Activity, Calcium, Magnesium, and Total Antioxidant in Uncontrolled Diabetic Type 2 Patients Treated with Daonil ® and Glucophage ® Maha F. AL-Smaism ‫الثالث-‬ ‫العدد‬ ‫التا

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    Abstract In this study 298 patients suffering from diabetes mellitus type 2 (150 male, and 148 female) aged between 35 to 67 years with a mean age of (45.11±12.03) were included. The study was carried out from first of November 2009 to the day 31 of May 2010.The samples were obtained from AlKassim hospital and Merjan Teaching Hospital in Hilla city . The study included three groups: Firstly: 149 patients with type 2 diabetes mellitus treatment with Daonil . Secondly: 149 patients with type 2 diabetes mellitus treatment with Glucophage .Thirdly: 83 apparently healthy subjects were chosen as healthy people. The results show a significant increase p<0.05 in Acetylcholinesterase AChE activity of patients treated with daonil and glocophage ≤5 years when compared with control group , while AChE activity found to be highly significant increase p<0.001 in patients treated more than five years when compared with ≤5 years and control groups. No differences were found in blood AChE activities between subgroups of each sample used in this study . Corrected total calcium and ionized concentrations in DM type 2 treated with daonil and glucophage groups ≤5 and more than five years found to were highly significantly increased p<0.001,when compared with that of the control, while there was a non-significant difference p>0.05 between the males and females when compared in the same group( control, daonil and glucophage ) in all duration. A significantly increased p<0.001 in the corrected total calcium concentration of DM patients treatment with daonil (more than five years) when compared with that of the patients treatment with glucophage . A significant increase p<0.05 in magnesium concentrations in diabetes mellitus patients (daonil, and glucophage) ≤5 years when compared to control group. On the other hand a highly significant increase p<0.001 of magnesium concentrations were found in sera of DM patients more than five years when compared to DM patients ≤5 years and control group .No significant difference were found between males and females in control group and patients groups. A significant decreased p<0.05 in total antioxidant(TAC) concentration in DM patients treatment ≤5 years with daonil and glucophage was found when compared with control groups .A highly significant increase of total antioxidant p<0.001 in sera of TCA of DM type 2 patients treated (6-15y) when compared with that of healthy control group and ≤5 years. No significant difference was found in the males and females of DM type 2 patients treated with daonil and glucophage (≤5y or 6-15 y) when compared with control group P>0.05. ‫الخالصة

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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