127 research outputs found
Questione di aria
No full textUn viaggio iconograficamente stupefacente tra scienza e arte nato grazie ai disegni degli alunni della classe Ia della Scuola Primaria "Pascoli" di Pavia (insegnanti: Poma Daniela, Pipia Sabrina, Gobetti Lorena) e sul filo di quanto osservato e sperimentato al Museo per la Storia dell’Università di Pavia.
Nel cahier de voyage a leporello è illustrata la parte finale, artistica, del progetto "Raccontare la scienza: oggetti, immagini, suoni tra museo e scuola" nato su iniziativa di Lidia Falomo e Gabriele Albanesi e che ha coinvolto, come ogni anno, molte classi di scuole del territorio, di diverso ordine e grado. All’interno di un’unica comunità di apprendimento sono state svolte, in successione, visite al Museo storico e tre tipi di laboratorio: scientifico (L.Falomo), sonoro (G.Mocchi) e artistico (G.Albanesi), per raccontare la scienza attraverso la sua storia e con una completa integrazione con l'arte figurativa e il suono. In questo caso i bambini sono arrivati, durante il laboratorio scientifico, all'individuazione di alcune proprietà dell'aria (occupa uno spazio, ha un peso, esercita una pressione, trasmette il suono ...) e hanno osservato e commentato ciò che accade togliendo l'aria da una campana di vetro (il suono non si propaga, l'acqua bolle, oggetti diversi raggiungono il fondo del tubo tutti nello stesso istante ...). Durante i laboratori successivi hanno prodotto suoni con la vibrazione delle labbra, li hanno riprodotti immettendo aria in un tubo, hanno sentito, visto, "toccato" le vibrazioni: il riso sul tamburo saltella per la vibrazione delle voci, la corda della chitarra pizzicata solletica al tatto ... Alla fine gli alunni hanno tradotto in forme e colori suoni, vibrazioni, emozioni
Identification of Novel Thermosensors in Gram-Positive Pathogens
No full textFil: Fernández, Pilar. Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET); Argentina.Fil: Ré, María Florencia. Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET); Argentina.Fil: De Mendoza, Diego. Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET); Argentina.Fil: Albanesi, Daniela. Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET); Argentina.Fil: Mansilla, María Cecilia. Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET); Argentina.Fil: Díaz, Alejandra Raquel. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Centro de Recursos Naturales Renovables de la Zona Semi-árida (CERZOS-CONICET); Argentina.Fil: Porrini, Lucía. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Microbiología; Argentina.Fil: De Mendoza, Diego. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Microbiología; Argentina.Fil: Albanesi, Daniela. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Microbiología; Argentina.Fil: Mansilla, María Cecilia. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Microbiología; Argentina
The distinctive roles played by the superoxide dismutases of the extremophile Acinetobacter sp. Ver3
No full textFil: Steimbrüch, Bruno A. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Microbiología. Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET); Argentina.Fil: Sartorio, Mariana Gabriela. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Microbiología. Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET); Argentina.Fil: Cortez, Néstor. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Microbiología. Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET); Argentina.Fil: Albanesi, Daniela. Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET); Argentina.Fil: Albanesi, Daniela. Plataforma de Biología Estructural y Metabolómica (PLABEM); Argentina.Fil: Lisa, María Natalia. Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET); Argentina.Fil: Lisa, María Natalia. Plataforma de Biología Estructural y Metabolómica (PLABEM); Argentina.Fil: Repizo, Guillermo Daniel. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Microbiología. Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET); Argentina
Immune functions and recruitment of plasmacytoid dendritic cells in psoriasis.
No full textPsoriasis is one of the most common chronic T cell-mediated diseases in humans. Among the most proximal event in the innate immunity cascade driving psoriatic inflammation is the secretion of type I IFN by activated plasmacytoid dendritic cells (pDC), a special DC subset strategically positioned in pre-psoriatic symptomless skin. There is an IFN-alpha signature in primary psoriatic plaques, and blocking of type I IFN signalling can prevent the expansion of pathogenetic T cells and development of psoriatic phenotype. Recently, we have demonstrated that pDC infiltration in psoriatic skin correlates with the expression of markers typical of early phases of psoriasis, whereas it is almost absent in long-lasting lesions. Importantly, pDC recruitment in psoriatic skin is strictly associated with the chemerin/ChemR23 axis, and is temporally active during psoriatic plaque development. Pro-chemerin is produced primarily by dermal fibroblasts, but also by mast cells and endothelial cells. Once secreted, it can be activated by enzymes produced by neutrophils and mast cells, which infiltrate early psoriasis lesions. These findings propose the chemerin/ChemR23 axis as a potential novel therapeutic target in psoriasis
Lateral strength Of urm piers: comparison between codified criteria and in-plane test results
No full textThe lateral resistance represents one of the most significant wall parameters to be used in the seismic analyses for the design/assessment of masonry buildings. In this article, an investigation on in-plane lateral strength of URM piers has been proposed thorough a comparison between the results from codified criteria and the outcomes of several experimental in-plane cyclic tests on masonry walls. In this context, a new database collecting the results of in-plane cyclic tests on unreinforced masonry piers, carried out within different research projects, has been devel-oped. The database consists of walls with bricks and blocks with different masonry materials (clay, lightweight aerated concrete, AAC, calcium silicate), bed-and head-joint typologies, di-mensions, boundary conditions, vertical applied loads and horizontal loading history. This source of information of consistent and reliable test results represents a necessary step into the process of definition of shared rules in the European context.Accepted Author ManuscriptApplied Mechanic
Prevalence of impaired glucose tolerance and diabetes type 2 in obese Italian children and adolescents.
No full text
Neoplasia in Turner syndrome. The importance of clinical and screening practices during follow-up.
No full textSensing membrane thickness: Lessons learned from cold stress
No full textThe lipid bilayer component of biological membranes is important for the distribution, organization, and function of bilayer spanning proteins. These physical barriers are subjected to bilayer perturbations. As a consequence, nature has evolved proteins that are able to sense changes in the bilayer properties and transform these lipid-mediated stimuli into intracellular signals. A structural feature that most signal-transducing membrane-embedded proteins have in common is one or more α-helices that traverse the lipid bilayer. Because of the interaction with the surrounding lipids, the organization of these transmembrane helices will be sensitive to membrane properties, like hydrophobic thickness. The helices may adapt to the lipids in different ways, which in turn can influence the structure and function of the intact membrane proteins. We review recent insights into the molecular basis of thermosensing via changes in membrane thickness and consider examples in which the hydrophobic matching can be demonstrated using reconstituted membrane systems. This article is part of a Special Issue entitled: The cellular lipid landscape edited by Tim P. Levine and Anant K. Menon.Fil: Saita, Emilio Adolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Albanesi, Daniela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: de Mendoza, Diego. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentin
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