162 research outputs found
Weight Development in Children and Adolescents with Obesity During the COVID-19 Pandemic
No full textClinical characteristics and cardiovascular risk profile in children and adolescents with latent autoimmune diabetes: Results from the German/Austrian prospective diabetes follow‐up registry
No full textJe früher bei Kindern und Jugendlichen mit Übergewicht eine standartisierte Lebensstilintervention begonnen wird, desto erfolgreicher und nachhaltiger die Maßnahme: Eine longitudinale k-means Clusteranalyse von 13.149 Patienten des APV Registers (#43)
No full textSupplementary Movie
No full textImpact of citrus extracts of different biotransformation level on cell migration of IPEC-J2 cells under challenge conditions. Representative video file of cell migration of IPEC-J2 cells pre-treated with citrus extracts for 6 h and stressed with tert-butylhydroperoxide (tBHP) after scratching. Cell migration is shown between 15 to 420 min.Supplementary Movie for "Combined acid hydrolysis and fermentation improves bioactivity of citrus flavonoids in vitro and in vivo" by Alice König, Nadiia Sadova, Marion Dornmayr, Bettina Schwarzinger, Cathrina Neuhauser, Verena Stadlbauer, Melanie Wallner, Jakob Woischitzschläger, Andreas Müller, Rolf Tona, Daniel Kofel and Julian Weghuber, 2023.</p
The Assessment of Eating Behaviour in Children Who Are Obese: A Psychological Approach. A Position Paper from the European Childhood Obesity Group
No full textObjective: This paper introduces health professionals to the different psychological models thought to influence eating behaviour in the absence of hunger in children who are obese and to propose a method of assessing these behaviours in practice. Methods: Clinical researchers from the European Childhood Obesity Group (ECOG) adopted an evidence-based approach to examine the literature concerning the assessment of eating behaviour in children who are obese. Studies published in English were filtered out of the medical and psychological literature from 1960 to the present, and the resulting bibliography was searched for relevant articles. Key themes from the current evidence were compiled and classified according to the underpinning psychological models. Based on the current evidence and the authors' combined clinical experience, a three-staged approach to assessment was agreed by consensus. Results: Valid and reliable tools for assessing and monitoring each of the three identified models (Dietary Restraint Theory, Emotional Eating and the Diathesis-Stress Model) are suggested for use in clinical practice, and the ECOG three-staged approach to assessing eating behaviours in the absence of hunger is described. Conclusions: This paper presents practical guidance on how to assess eating behaviour in the absence of hunger in children who are clinically obese and suggests a focus for future research. (C) 2014 S. Karger GmbH, Freibur
Clinical characteristics and outcomes of children, adolescents and young adults with overweight or obesity and mental health disorders
No full textAbstract
Background
Mental disorders are important comorbidities in youth with obesity. Aim was to describe the clinical characteristics and outcome of youth with overweight or obesity having comorbid mental disorders.
Methods
Data from children, adolescents, and young adults (age 6–30 years) with overweight or obesity and mental disorders (depression, anxiety disorder, eating disorder, attention deficit disorder (ADHD)) from 226 centers in Germany and Austria participating in the Adiposity Patient Registry (APV) were analyzed and compared with those without reported mental disorders using regression modeling.
Results
Mental health comorbidity was reported in a total of 3969 out of 114,248 individuals with overweight or obesity: 42.5% had ADHD, 31.3% anxiety disorders, 24.3% depression, and 12.9% eating disorders. Being male (OR 1.39 (95%CI 1.27;1.52)), of older age (1.42 (1.25;1.62)), or with extreme obesity (1.45 (1.30;1.63)) were most strongly associated with mental health comorbidity. Regression analysis showed that mean BMI-SDS was significantly higher in the group of individuals with depression and eating disorders (BMI-SDS 2.13 (lower; upper mean:2.09;2.16) and 2.22 (2.17;2.26)) compared to those without reported mental health comorbidity (BMI-SDS 2.008 (2.005;2.011);
p
< 0.001). In youth with ADHD, BMI-SDS was lower compared to those without reported mental disorders (BMI-SDS 1.91 (1.89;1.93) vs 2.008 (2.005;2.011);
p
< 0.001). Proportion of severe obesity was higher in individuals with depression (23.7%), anxiety disorders (17.8%), and eating disorders (33.3%), but lower in ADHD (10.3%), compared to those without reported mental disorders (13.5%,
p
< 0.002). Proportions of dyslipidaemia and abnormal carbohydrate metabolism were not different in youth with and without reported mental health comorbidity. BMI-SDS change after one year of lifestyle intervention program ranged between −0.22 and −0.16 and was similar in youth without and with different mental disorders.
Conclusion
Health care professionals caring for youth with overweight or obesity should be aware of comorbid mental disorders and regular mental health screening should be considered
Effect of 3-month treatment of children and adolescents with familial and polygenic hypercholesterolaemia with a soya-substituted diet
No full text24th European Childhood Obesity Group (ECOG) Meeting, Salzburg, Austria, November 13-15, 2014 Abstracts
No full text69 Adipositastherapie bei Kindern und Jugendlichen in der COVID19-Pandemie: Daten aus der Adipositas-Patienten-Verlaufsdokumentation (APV)
No full textRecommendations for improving clinical trial design to facilitate the study of youth-onset type 2 diabetes
No full textBackground The prevalence of type 2 diabetes is increasing in youths and differs from adult-onset type 2 diabetes in its characteristics and progression. Currently, only two drugs are approved for youth-onset type 2 diabetes and many patients are not meeting glycemic targets. Clearly, there is an urgent need to complete clinical trials in youths with type 2 diabetes to increase the therapeutic choice for these patients. However, factors such as limited patient numbers, unwillingness of patients to participate in trials, failure to meet strict inclusion and exclusion criteria, and poor clinic attendance have limited the size and number of trials in this complicated patient demographic. Recommendations This is a narrative opinion piece on the design of clinical trials in youth-onset type 2 diabetes prepared by researchers who undertake this type of study in different countries. The review addresses possible ways to enhance trial designs in youth-onset type 2 diabetes to meet regulatory requirements, while minimizing the barriers to patients' participation. The definition of adolescence, recruitment of sufficient patient numbers, increasing flexibility in selection criteria, improving convenience of trial visits, requirements of a control group, possible endpoints, and trial compliance are all considered. The authors recommend allowing extrapolation from adult data, using multiple interventional arms within future trials, broadening inclusion criteria, and focusing on endpoints beyond glucose control, among others, in order to improve the successful completion of more trials in this population. Conclusions Improvements in trial design will enable better recruitment and retention and thereby more evidence for treatment outcomes for youth-onset type 2 diabetes
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