49 research outputs found
Omphalina : newsletter of Foray Newfoundland and Labrador, vol. 02, no. 08 (2 October 2011)
No full textEditorial -- Foray matters -- $1,000 question / Andrus Voitk -- Underground boletes / Andrus Voitk -- Peltigera aphthosa / Mac Pitcher -- Puffballs / Jim Cornish -- The juniper / Andrus Voitk -- Toxicology report / Michael Beug -- Daniel Gabriel Fahrenheit / Andrus Voitk -- Parallel evolution revisited / Andrus Voitk -- Mail -- Partners -- Foray 2012.Pagination error: p. 20 misnumbered 34. -- Frequency: irregular.Omphalina : newsletter of Foray Newfoundland and Labrador, "an amateur, volunteer-run, community, not-for-profit organization with a mission to organize enjoyable and informative amateur mushroom forays in Newfoundland and Labrador and disseminate the knowledge gained" (vol. 1, no. 2, p. 2)
Kardiale Effekte der Autoantikörper von Patienten mit dilatativer Kardiomyopathie auf isolierte, druckkonstant perfundierte Rattenherzen an der Langendorff-Anlage
No full textBei Patienten mit DCM und Myokarditis sind Störungen der zellulären und humoralen Immunität bekannt. Im Serum dieser Patienten werden unterschiedliche zirkulierende kardiale Autoantikörper gefunden, die eine kardiodepressive Wirkung haben. Diese Autoantikörper können durch die Immunadsorption (IA) aus dem Plasma extrahiert werden. Es wurden die Einflüsse des durch die IA gewonnenen Eluates mit den darin enthaltenen Autoantikörpern von 10 DCM Patienten auf die Kontraktilität, die Herzfrequenz und den Koronarfluss an isolierten Rattenherzen zu untersuchen. Die Ergebnisse unserer Studie zeigen eine dosisabhängige Reduktion der systolischen und diastolischen Funktion im Vergleich zur Kontrollgruppe. Die Koronarperfusion nahm sowohl in der Kontrollgruppe als auch, noch ausgeprägter, in der DCM-Gruppe ab. Die Herzfrequenz blieb in beiden Gruppen stabil. Hämodynamische Phänomene einer Herzinsuffizienz können somit durch Perfusion mit myokardialen Autoantikörpern imitiert werden. Jedoch können die bisher bekannten kardialen Antikörper die beobachteten in-vitro Effekte nicht komplett erklären.Cardiac autoantibodies may play a functional role in cardiac dysfunction of patients suffering from dilated cardiomyopathy (DCM). 10 patients with DCM were treated with immunoadsorption (IA). IA was also performed with plasma taken from healthy donors. The antibodies eliminated and purified by IA were collected and dialyzed. Rat hearts were isolated and perfused retrogradely via the aorta in Langendorff mode. Durin pressure-constant perfusion of the hearts the influence of diluted antibodies on systolic and diastolic function and coronary flow rates was analyzed. Antibodies obtained from controls did not influence systolic and diastolic function. In contrast, during pressure-constant perfusion DCM antibodies collected caused immediate and dose-related decrease of systolic and diastolic cardiac function. The heart rate did not change significantly in both groups. In comparison to controls coronary flow rates were significantly reduced. Antibodies received from DCM patients impair systolic and diastolic cardiac function and simultaneously these antibodies also negatively influence coronary perfusion
An Unknown Odyssey of the Płock Monuments
No full textDuring the Second World War the German invaders plundered the Płock cathedral and took away its monuments: a chalice with a paten which were a gift from the prince Conrad I (1239), a herm reliquary of St Sigismund (1370) along with the Piast crown (13th c.). These were the objects of religious cult of great value. That is why they can be treated as the treasures of national culture. They were transported to Germany on 18th January 1945, and the person who safeguarded them was Berta Thiergat, the clerk of the Town Council. Being certain that they were German goods, she brought them to Bad Salzuflen in Westphalia. When she had learned that it was not the case, she made a contact with a Polish chaplain who served in the British army, and made the monuments return to Poland. The communist authorities kept them in the National Museum in Warsaw. They returned at their original site as late as on 6th November 1980.
The history of the so-called Płock Bible was different. It was plundered in 1941 along with a valuable collection of books from the Library of the Theological Seminary in Płock, and they were taken to Königsberg. Fleeing the East in 1945, the Germans took thence the Bible which, somehow, first arrived at the treasury of Georg-August Universität in Göttingen. After some strong diplomatic efforts the delegate of this university (prof H. J. Beug) returned the statute to the Płock bishop, Bogdan Sikorski, as late as on 13th September 1978. Fortunately, thus the odyssey of the Płock monuments was brought to completion. The author has gathered the documentation dealing with the war history of the regained treasures of national culture
Takayasu’s arteritis: a case with relapse after urgent coronary revascularization
No full textAbstract Background Vasculitides are commonly unrecognized causes of coronary stenosis and myocardial ischemia. We report on a 24-year old patient with Takayasu’s arteritis who underwent urgent percutaneous coronary intervention, suffered from symptomatic restenosis of the left main coronary artery during standard immunosuppressive therapy. Case presentation A 24-year old woman was referred for coronary angiography because of typical progressive angina pectoris. On bicycle ergometry, there were both reproducible symptoms and deep ST segment depressions on precordial leads. Semi-selective angiography of the left coronary artery revealed high-grade ostial stenosis. Because of persistent angina pectoris and electrocardiographic signs of acute myocardial ischemia, immediate percutaneous coronary angioplasty with subsequent implantation of an everolimus-eluting stent was performed. This intervention was performed with excellent angiographic results. Because of several concomitant criteria including hypoechogenicity on postprocedural intravascular ultrasonography, the diagnosis of Takayasu’s disease was made. The patient was treated with prednisolone and cyclophosphamide for 5 months. Because of recurrent angina pectoris, another coronary angiography was performed, which revealed high-grade in-stent-restenosis. Immunomodulatory therapy was switched to high-dose prednisolone and the anti-IL-6 receptor antagonist tocilizumab. The high-grade in-stent-restenosis persisted, and aortocoronary bypass graft surgery was performed with two saphenous vein grafts to the left anterior descending and circumflex artery. Since then, the patient has been doing well for 2 years. Conclusion In cases of treatment refractoriness during standard immunosuppressive therapy, more recently developed biological compounds may offer an alternative strategy
The pollen and macrofossil content of silt, sand and peat layers from gravel pits near Northeim, Lower Saxony, Germany
No full textThe data sets presented in this report are the result of an extensive pollen analytical and macrofossil study of the sediment of former oxbows exposed in gravel pits about 2 km northwest of the city of Northeim, Lower Saxony, Germany. Here where the river Rhume discharges into the river Leine vast exploitable gravel deposits were accumulated. When the author and Dr. E. Brunotte (Geographical Department, University of Göttingen, later Cologne) visited the site in the years 1984 and 1985 the area south of the "Großer See" (Great Lake) was a gravel plain with abandoned gravel pits and relicts of long quarry walls, an area almost completely devoid of the former about 2 m thick alluvial clay cover with its two young soils. The clay had been removed to allow gravel mining. The area is now flooded and part of the Great Lake. The water table of the lake lies 112 m above NN. The adjacent dry land is a few meters higher only. The study was stimulated by professor Dr. Brunk Meyer (Pedological Department, University of Göttingen) who - when visiting the Northeim gravel pit area - found hazel nuts falling out of a former quarry wall.
In the quarry walls numerous cross sections of former channels cut into the gravel and filled up with fine limnic mineral material - at one place even with some peat on top - could be observed. The channels document former oxbows of the river Rhume. Many fillings were truncated, often eroded to a few decimetres of limnic sediment overlain by gravel or sand. Visible hiatus are numerous in the sedimentary record; more are likely to be detected - especially in the silty layers - by a careful investigation of the profiles. Apparently the meandering river Rhume did often change its bed in the past, leaving oxbows which were filled up.
The stratification of a great number of sections accessible in the walls of the gravel pits and along an altogether more than 600 m long pit wall was studied. This report deals with profiles taken from the walls of gravel pits A and B, from a long quarry wall (C) and with sample E taken from a silt layer next to a well preserved oak trunk found in the gravel during the excavations (see the map).
As expected only samples from limnic and peaty layers were suitable for pollen and macrofossil analyses. Of the 120 samples prepared for pollen analysis only 84 contained pollen in quantities sufficient for a reliable interpretation (see the tables).
Thanks to the excellent state of knowledge of the postglacial development of the vegetation in the nearby Harz Mountains and their foreland (Beug 2017) most of the pollen samples can be assigned to one of the established pollen zones. The samples date from different phases of the Holocene, the oldest from Younger Dryas times, the youngest from a period with arable farming as the pollen grains of anthropogenic indicators like Triticum type, Cerealia type, Secale, Linum usitatissimum, Plantago lanceolata and Centaurea cyanus prove. No profile representing the complete Holocene was found.
One bulk sample of fen peat and three pieces of wood from Pit A could be radiocarbon dated. The results are presented below the pollen content tables both as BP ages and as calBC ages (calendar years, calibrated with CalPal_2007_HUL). The radiocarbon ages - especially that of the fen peat - differ to some degree from the ages suggested by the pollen content, most likely due to erosion and redistribution not only of silt and sand, but also of organic material like pollen grains and pieces of wood at times of flooding, a phenomenon which must have occurred often in the special environment of the Rhume-Leine floodplain. Thus pieces of "old" wood might be found in "young" sediment and reworked (i.e. older) pollen might obscure the age of the pollen spectra. Reworked pollen cannot be distinguished from autochthonous pollen. Therefore single samples or short sequences might not be datable. Reliable dating of oxbow sediment samples is possible - despite the presence of reworked pollen - if the pollen spectra reflect characteristic changes of the vegetation like the spreading of Fagus or if stated pollen association is specific for a certain period. Pollen analysis can hardly contribute much to vegetation history
Analysis of trap mechanisms responsible for Random Telegraph Noise and erratic programming on sub-50nm floating gate flash memories
No full textS.67-71In this work we present a systematic investigation concerning the correlation of Random Telegraph Noise (RTN) with erratic bits in sub-50 nm floating gate NAND memory cells. Both effects are compared with respect to their implication in reliability and cell operation parameters of sub-50 nm flash devices. Related measurements were performed on a test chip with large floating gate cell arrays in NAND architecture. The analysis methods for both effects are presented comparing the magnitude and cycling stress dependency in detail. Additionally, two integration concepts with different memory cell sidewall oxidation approaches are discussed effecting differently the RTN and erratic programming behavior. Based on the characterization results we conclude that both effects are originating from different trap mechanisms. Possible explanations for the different trap mechanisms and locations are discussed
Improvement of 48 nm TANOS NAND cell performance by introduction of a removable encapsulation liner
No full textS.88-89This paper presents charge trapping (CT) cells integrated with a sacrificial liner at the word line (WL) side wall which improves significantly the erase and retention characteristics, currently the main issues in CT memory devices
