1,720,994 research outputs found
Combined transconjunctival sutureless three-port vitrectomy and scleral fixation of intraocular lens
No full textPurpose: The aim of this article is to describe an innovative and minimally invasive surgical technique for posterior vitrectomy combined with secondary intraocular lens implantation, using a sutureless scleral fixation Carlevale intraocular lens (I71 FIL SSF Carlevale lens. Soleko IOL Division, Italy). Methods: The technique was conducted with only three transconjunctival sclerotomies and a corneal tunnel to perform intraocular lens explantation, posterior vitrectomy and Carlevale intraocular lens implantation. It is easier, quicker, and less invasive than the traditional technique with conjunctival peritomy, two scleral flaps and five sclerotomies. Results: Surgery was performed uneventfully on three eyes of three patients. Two of them presented a luxation of the intraocular lens into the vitreous chamber, while one patient presented an intraocular lens subluxation. No complications were observed after a 5 to 8 months of follow-up. The intraocular lenses were well positioned, no conjunctival erosion was noted, and the intraocular pressure remained normal at all stages. Conclusions: This is the first report of a combined procedure of IOL explantation, posterior vitrectomy and secondary IOL implantation using only three transconjunctival sclerotomies. This appears to be less invasive and it causes less discomfort to the patient. We suggest considering this technique in all those cases requiring a combined procedure in absence of a proper capsular support
Obesity paradox in coronary artery bypass grafting: Myth or reality?
Full text linkObjective: A high body mass index has been suggested to be protective in patients with coronary artery disease and in those undergoing coronary artery bypass grafting (CABG). However, these conflicting results might be related to the different risk profiles among the various body mass index categories. We sought to clarify the effect of varying degrees of excessive body weight on hard clinical outcomes in patients undergoing CABG.Methods: A retrospective analysis of prospectively collected data was conducted to investigate the effect of a high body mass index on early and late mortality after first-time isolated CABG. Propensity score matching was used to adjust for confounding factors.Results: The study sample consisted of 3269 normal weight, 6662 overweight, 3821 obese, and 211 morbidly obese patients. After matching, early mortality was not affected by overweight (mean difference, 0.7%; 95% confidence interval [CI], -0.2% to 1.5%), obesity (mean difference, 0.5%; 95% CI, -0.7% to 1.7%), and morbid obesity (mean difference, 1.6%; 95% CI, -1.0% to 1.0%), regardless of the patients' risk profile according to the European system for cardiac operative risk evaluation. Overweight status was not protective for late death (hazard ratio, 1.05; 95% CI, 0.9-1.08; P = .4). Compared with normal weight patients, both obese and morbidly obese patients had a higher risk of late death (hazard ratio, 1.22; 95% CI, 1.07-2.66; P = .006 for obese patients; hazard ratio, 1.36; 95% CI, 0.74-2.49; P = .3 for morbidly obese patients).Conclusions: Obesity did not increase operative mortality, but it was associated with reduced late survival in patients undergoing primary isolated CABG. Our results raise concerns in supporting any protective effect of obesity in cardiovascular disease, specifically in patients undergoing surgical myocardial revascularization
Noncongenital juvenile-onset bilateral lamellar cataract in 1p36 deletion syndrome
No full textWe report the case of a 16-year-old girl with 1p36 deletion syndrome, who experienced visual loss in both eyes for 2 months because of lamellar cataracts. Mutations on some 1p36 genes in both experimental models and humans may be associated with cataract. This is the first detailed description of acquired juvenile-onset bilateral cataract with 1p36 deletion
Transient Clouding of a Sutureless Scleral Fixated Hydrophilic Intraocular Lens with Spontaneous Resolution: A Case Report and in vitro Experimental Test
No full textA 83-year-old woman underwent phacoemulsification in the left eye, complicated by posterior capsular rupture and dislocation of nuclear fragments in the vitreous cavity. She was left aphakic and referred to the Clinica Oculistica, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy. After 2 days, she underwent pars plana vitrectomy, with removal of the nuclear fragments, and secondary intraocular lens (IOL) implantation. The lens used was a sutureless scleral fixation Carlevale lens (I71 FIL SSF Carlevale lensTM. Soleko IOL Division), which was delivered to the operating theatre on the morning of the operation. During the implantation, it appeared opaque, without any deposit on its surfaces. The lens was not removed. On the next day, the lens was transparent, and it remained clear at the following control visits. An in vitro experimental test demonstrated that 25% hydrophilic polymers are vulnerable to thermal shock, developing an opacification which resolves after temperature stabilization of the lens
Single-hand preloaded intraocular lens implantation through a screw-type single use injector
No full textIntroduction: The most common intraocular lens (IOL) injectors are syringe- and screw-type. Screw-type injectors are useful to control IOL injection speed, but the surgeon needs to use both hands during implantation. It may result in a lack of eye stability, especially under topical anesthesia. Methods: In this paper a single hand implantation technique is described. The second hand is used to hold a second instrument into the anterior chamber in order to stabilize the eye and aid the correct IOL positioning into the capsular bag. Results: Surgery was performed uneventfully on six eyes of four patients, affected by senile corticonuclear cataract. In all cases the operation was conducted without complications. All the IOLs were well centered. Conclusions: The technique is safe and easy to replicate, however the shape of the injector plunger needs to be adequate
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Fungal endogenous endophthalmitis secondary to magnusiomyces capitatus
Full text linkWe report the case of a 68-year-old immunocompetent patient with a dilatation of the ascending aorta, intraluminal vegetations, and pseudoaneurysmatic bulging who presented with unilateral fungal endogenous endophthalmitis 8 days after coronary angiogram. The isolated pathogen resulted to be Magnusiomyces capitatus, a filamentous, yeast-like fungus that can be commonly found in normal human microflora, with an immunosuppression-related pathogenicity. A literature research revealed a single case of ophthalmic infection - a keratitis - caused by this pathogen. Furthermore, we add a review of mycotic endophthalmitis related to aortic infection. (c) 2019 The Author(s) Published by S. Karger AG, Base
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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