1,720,956 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Pathophysiology of bone metastases in breast and prostate cancer with the aid of in vivo mice models: effect of hormonal analogues
No full textPathophysiology of Bone metastases in breast and prostate cancerwith the aid of in vivo mice models; Effect of hormonal analoguesBone metastases are a frequent compilation of cancer, occurringin up to 70 percent of patients with advanced breast and prostate cancer.An extensive line of research has documented that bones constitutes afavorable microenvironment for homing prostate and breast cancercells. Metastases can be osteoblastic, osteolytic, or mixed; they resultfrom increased osteoclastic activity due to an imbalance betweenRANK ligand expression and OPG expression. In breast cancer,osteolytic lesions are most common, whereas in prostate cancer,osteoblastic lesions predominate. In the present work we tested:• The anticancer effects of dexamethasone (DEX), octreotide(OCT), docetaxel (DOC) and their combination on the TRAMP-C1prostate cancer model, in vitro and in vivo.• The anticancer effects of DEX, OCT, adriamycin (ADR) andtheir combination on 4T1 breast cancer model, in vitro and in vivo.• TRAMP-C1 and 4T1 cells were first characterized forsomatostatin receptors (SSTR 1-5) expression and then inoculated ontothe femur of C57Bl and BALB/c mice, respectively. Investigationprotocols included TRAMP-C1 and 4T1 cell proliferation, migrationand invasion assays, in vitro, and the analysis of radiographic images ofbone lesions and the survival of diseased animals.We documented that:• The TRAMP-C1 cells express the SSTR-1, -2, -3 and -5 and arecapable of producing osteoblastic lesions onto the femur of C57Blmice. DEX, OCT and DOC exerted significant anticancer effects onTRAMP-C1 cell proliferation, invasion and migration assays, in vitro.The triple combination treatment scheme (DEX-OCT-DOC) showed asignificant synergistic/additive anticancer effects, reducing by 5-foldthe dose of DOC required for maximal anticancer effects, in vitro. Inaddition, the triple combination regimen produced significantanticancer effects on TRAMP-C1 cell invasion assays better than anysingle agent treatment scheme, with the exception of DEX, whichproduced the maximal inhibitory effect on TRAMP-C1 cell invasionassay. Furthermore, DEX and OCT, when administered as single orcombination treatment schemes did not produce significant anticancereffects on the overall survival of the diseased animals, according to thecriteria established by NCI [Treated animals vs Controls (T/C >125%)].DOC produced a significant anticancer effect, which reflected to theshrinkage of the bone lesions and to a significant increase of the overallsurvival of diseased animals (T/C = 133%), however, the administration of DEX plus OCT regimen prior to DOC therapysignificantly improved the DOC anticancer effects on bone lesions andoverall survival (T/C = 150%). This data suggest that neoadjuvantadministration of DEX plus OCT regimen can improve the anticanceractions of DOC on TRAM-C1 prostate cancer models in vitro and invivo.• The 4T1 cells express the SSTR-2, -3, -4 and -5 and are capableof producing osteolytic lesions onto the femur of BALB/c mice. OCTand DEX induce a dose dependent cell death in vitro. When OCTcombined with DEX showed an antagonistic effect on 4T1 cell line.The combination of OCT plus DEX was ineffective on growthinhibition. The combination of OCT and DEX with ADR had also anantagonistic effect in 4T1 cell line. On the other hand, the singletreatment schemes revealed that the invasion capacity of 4T1 cells wasinhibited by 26% using DEX, by 15% using OCT, and increased by13.2% using ADR single- agent treatment schemes. However, the triplecombination treatment scheme resulted in stimulation by 37.3% of the4T1 cell invasion capability.OCT does not result in significant increase of lifespan of the 4T1 bearing mice, as a single agent (T/C = 105.3%). When we treated 4T1breast cancer bearing mice with DEX and DEX plus OCT, theirmedium survival time (MST) was reduced (T/C= 97.4 % and 94.7 %respectively) to the MST of the untreated animal group (controlT/C=100%). On the other hand, when ADR was used alone, asignificant increase to the lifespan of the mice (T/C = 144.7 %).However, when all three drugs were used in combination, the antitumoractivity of ADR was neutralized (T/C = 110.5%). Also, the animalstreated with combination of the drugs developed more extensiveosteolytic bone destruction than the untreated animals or the animalstreated with one drug alone. This data indicated that the combination ofOCT with DEX in the treatment of 4T1 mouse breast cancer isineffective. The simultaneous use of these drugs should be carefullyconsidered because they also neutralized the antitumor activity of theADR
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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