1,721,010 research outputs found
Trichinellosis
No full textTrichinellosis is a worldwide zoonosis caused by the parasitic nematodes
belonging to the Trichinella genus.
This chapter describes the different aspects of epidemiology of infection, the life
cycle of the parasite and the host immune response to the different species of
Trichinella in humans, as well as in rodents which represent the most studied
experimental model. The roles of antibodies, T cells, mast cells, eosinophils and
neutrophils in immune responses to this nematode are considered in experimental
as well as in human infections. Immunopathological aspects of infection are also
illustrated.
Particular emphasis is given on the clinical diagnosis of trichinellosis which is
difficult because of the lack of pathognomonic signs or symptoms. Therefore,
anamnestic data are of great importance in diagnosing the infection. High eosinophilia
and increased creatine phosphokinase (CPK) activity in the serum are the
most frequently observed laboratory features, but only the finding of parasites in a
muscle biopsy and the detection of specific circulating antibodies can confirm the
diagnosis. The medical treatment includes anthelmintics (mebendazole or
albendazole) and glucocorticosteroids.
A section is devoted to control measures, including a possible vaccine for which
several molecules are under investigation
Letter to the editor discussing the article "curved tunnel' sign on MRI: a typical radiological feature in hepatic trichinellosis"
No full textContribution à l'étude de la trichinose du sanglier (Sus scrofa l. 1758). Résultats d'une enquête epidémiologique dans le camp militaire de Canjuers (Var)
Full text linkL'auteur présente une étude expérimentale menée sur 1321 sangliers abattus sur le camp militaire de Canjuers dans le Var au cours des cinq saisons de chasse 95-96, 96-97, 97-98, 98-99 et 99-00. L'objectif était double, d'une part la sécurité sanitaire des consommateurs de la venaison vis à vis de Trichinella spiralis et d'autre part, l'approche de la prévalence de la trichinellose dans la population de sangliers présente sur le camp. Des portions musculo-tendineuses de diaphargme, prélevées sur chaque animal, ont constitué le matériau nécessaire à cette étude. La recherche de trichine a été effectuée par digestion artificielle à la pepsine chlorhydrique. Aucun prélèvement ne s'est révélé porteur de parasite. Le sexe et le poids des animaux, également communiqués par les chassseurs, ont permis d'appréhender la structure d'une population méditerranéenne de sanglier soumise à une pression de chasse
Meat sources of infection for outbreaks of human trichinellosis.
Full text linkTrichinellosis is one of the most important foodborne zoonotic diseases, with worldwide distribution. While human risk for trichinellosis has historically been linked to pork, modern pork production systems and slaughter inspection programs have reduced or eliminated pork as a source for trichinellosis in many countries. While pork may no longer pose a significant risk for trichinellosis, many other animal species may be hosts for Trichinella species nematodes and when human consume meat from these animal species, there may be risk for acquiring trichinellosis. This review article describes the various non-pork meat sources of human trichinellosis outbreaks, where these outbreaks have occurred and some of the factors that contribute to human risk. The literature reviewed here provides evidence of the persistence of Trichinella as a human health risk for people who eat meat from feral and wild carnivores and scavengers, as well as some herbivores that have been shown to harbor Trichinella larvae. It points to the importance of education of hunters and consumers of these meats and meat products
Recherches structurales sur les accidents triasiques du sud-ouest de l'Aquitaine.
No full textForma parte del art.: Recherches structurales sur les accidents triasiques du sud-ouest de l'Aquitaine (283 p. + 8 h. pleg. de map.
- …
