1,721,127 research outputs found
Identità culturale e percezione linguistica in un campione di classi elementari – prime osservazioni
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Caratterizzazione archeometallurgica di alcuni manufatti di ferro del santuario di Pyrgi
No full textStress granules in Ciona robusta: molecular evolution of TIAR and TTP and early evidence of their gene expression under stress conditions induced by metals.
No full textMicrobiological diagnostic protocol for prosthetic joint and fracture fixation devices infections from the Italian Association of Clinical Microbiologists (AMCLI)
No full textStress granules in Ciona robusta: molecular expression of tiar and ttp and early evidence of their gene expression under stress conditions induced by metals
Full text linkStress granules are non-membranous cytoplasmic foci composed of messengers (not translated), ribonucleoproteins, translation initiation components and other additional proteins, that represent a primary mechanism by which gene expression is rapidly modulated when cells are subjected to adverse environmental conditions. Very few works have been devoted to study the presence ofmolecular components of stress granules in invertebrate animals. In this work, we characterized, for the first time in the solitary ascidian Ciona robusta, the genetic sequences of two important protein components of stress granules, TIAR (TIA-1 related to proteins) and TTP (tristetraprolin), and carried out the first studies on their gene expression. The sequences characterized for tiar and ttp genes have allowed to start a study on the molecular evolution of these proteins in animals: for TIAR the obtained results are consistent with recent phylogenetic analysis that place tunicates as sister group of vertebrates, whereas the phylogenetic position of TTP remains still uncertain. The data on mRNA expression, provided by qRT-PCR analysis, are absolutely the first obtained in non-mammalian animals. As expected, the exposure to each metal (Cu, Zn and Cd) led to a generalized decrease in mRNA expression levels for both TIAR and TTP, suggesting that the metal accumulation induce acute stress and the inhibition of the transcription of tiar and ttp genes. The data presented here improved our knowledge about the molecular evolution anti-stress proteins in metazoans and emphasize the importance of the transcription of tiar and ttp genes, which represents an efficient physiological response allowing C. robusta to survive in the presence of metals in the marine environment (Supported by M.I.U.R. grant)
Pincer-like claws in centipedes (Chilopoda): multiple evolutionary origin of similar form and serial pattern
No full textIn most Chilopoda, the walking legs end in a
single-tip claw usually accompanied by short accessory
spines. Instead, in all species of three small and only distantly
related geophilomorph taxa (Diphyonyx, Neogeophilidae,
Eucratonyx), the claws of an anterior set of leg
pairs are unusually pincer-like. By integrating different
microscopic techniques, including confocal laser scanning
microscopy, we found that these modified claws are very
similar in form, internal structure, and pattern of variation
in shape along the trunk in all three taxa: the claws are
distinctly swollen and bent, provided with peculiar bulges,
and flanked by a conspicuous additional branch, either
cylindrical or flattened, which overreaches the tip of the
claw; instead, the internal cuticular features are not modified
with respect to the condition in the other centipedes,
claiming against the possibility of controlled abduction/
adduction between claw and branch. Irrespective of the
total number of leg pairs (63–129), the claws change
gradually from pincer-like to usual shape invariantly in the
range spanning between the 34 and the 45% of the total
number of leg pairs. Despite these similarities, pincer-like
claws originated independently in the three taxa, and by
way of fundamentally different changes, either by the
dramatic modification of the already existent anterior
accessory spine (Diphyonyx, Neogeophilidae) or by the production of a novel cuticular projection (Eucratonyx).
Moreover, their shared pattern of variation along the body
was most probably constrained by already operating
developmental processes controlling the longitudinal patterning
of the trunk
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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