196,235 research outputs found
UWB Network Coexistence and Coordination: a Cognitive Approach
No full text[C4] D. Domenicali, L.De Nardis, M.-G Di Benedetto, “UWB Network Coexistence and Coordination: a Cognitive Approach”, GTTI 2007, Rome, June 18-20, 2007
Le aperture domenicali e festive della Distribuzione Moderna
No full textIl lavoro si propone di approfondire l'impatto economico e sociale della legislazione relativa alle aperture degli esercizi commerciali nei giorni festivi e domenicali
Recensione a M. Foucault, Le courage de la vérité. Le gouvernement de soi et des autres II. Cours au Collège de France 1984 (Gallimard-Seuil, 2009)
No full textRecensione a M. Foucault, Le courage de la vérité. Le gouvernement de soi et des autres II. Cours au Collège de France 1984 (Gallimard-Seuil, 2009)
Una decade di giurisprudenza costituzionale. Le principali tendenze dopo la sentenza n. 22 del 2012
No full textNello scritto si delineano i punti fissati dalla storica decisione n. 22 del 2012, fondamentale tratto dell’argine costruito dagli organi di garanzia all'esercizio dei poteri coinvolti nella decretazione d’urgenza, alcuni dei quali confermati in veri e propri filoni, altri invece rimasti incipit di un percorso ancora da svolgere. Si mettono in luce alcune criticità di tale giurisprudenza ma anche quegli spunti provenienti dalla prassi giurisprudenziale che possono far sperare in ulteriori avanzamenti nel controllo di legittimità sulla decretazione d’urgenza
Identità personale in internet: il diritto all’oblio e la deindicizzazione sui media online
No full text
Senility
No full textSenility is a term used to describe a decline in an older adult’s physical and cognitive health. Like dementia, senility can cause changes in mental health, such as memory loss or a decline in judgment. But senility symptoms can also include physical changes such as:
Reply
No full textWe thank Dr. Braillon and Dr. Naudet for their interest in our review article.1 Based on their comments, several aspects need to be clarified and pointed out. First, we addressed a specific patient population presenting alcohol use disorder (AUD) and alcohol‐induced chronic liver disease (ALD) in an advanced stage. The cited Cochrane review 2 appeared after the acceptance of our review and, most important, dealt with the use of baclofen in AUD, with and without liver disease. It is relevant to outline that all randomized and open studies assessing the efficacy of baclofen in patients with AUD and ALD clearly showed that this favors the maintaining of abstinence from alcohol even at a low dose (30 mg/day), a result fully confirmed by a recent randomized trial.3 Second, when discussing about the approach to patients with an advanced (end‐stage) liver disease, which was the matter dealt with in our review, it cannot be under‐rated that the approved medications are contraindicated in this context, because of the risk of either liver toxicity (naltrexone and disulfiram) or hepatic encephalopathy (acamprosate). Thus, topiramate and baclofen only remain even though they have to be used off‐label. Third, there is no doubt that abstinence is the sole goal to be achieved in patients with end‐stage liver disease. Indeed, the perspective of the “harm reduction” was not even mentioned in our review. Fourth, baclofen adverse events and poisoning have been reported with much higher doses than those indicated in ALD. In this context, baclofen safety is also endorsed by the European Association for the Study of the Liver, clearly stating that topiramate and baclofen represent the safest anticraving drugs.4 Finally, we would like to recall that the French ANSM (Agence nationale de sécurité du medicament) has recently approved the use of baclofen for the treatment of AUD with the warning not to exceed 80 mg/day.5 All considered, in a context where the interruption of abstinence could be rapidly fatal, once nonpharmacological attempts have failed and approved medications are risky, we think that available evidence fully justifies the use of baclofen
Formazione e crisi del Governo Forlani: un governo di passaggio verso il pentapartito
No full textL’esperienza del governo Forlani, nel momento genetico ma soprattutto nei momenti di affanno e in quello conclusivo, conferma, seppur con meno evidenza rispetto ad altri esecutivi in carica sotto la stessa presidenza, il ruolo specifico del Presidente Pertini nella stabilizzazione della forma di governo. Le particolari condizioni storiche e politiche hanno fatto sì che, proprio a partire dal momento in cui è finito, dopo il 1978, il governo c.d. di unità nazionale, si riaccentrasse nelle mani del Presidente della Repubblica la garanzia dell’unità nazional
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