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Left atrial enlargement and risk of ischemic stroke in elderly treated hypertensive patients
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Metabolic Syndrome and Cardiovascular Risk in Elderly Treated Hypertensive Patients.
No full textBackground: The independent prognostic significance of the metabolic syndrome (MetS) in the elderly is not yet clear. We investigated the association between MetS and cardiovascular risk (composite endpoint of stroke and coronary events) in elderly treated hypertensive patients.
Methods: Cardiovascular outcome was evaluated in 1191 elderly treated hypertensive patients (>60 years). Among them, 578 (48.5%) had MetS according to a modified joint interim statement definition (body mass index in place of waist circumference).
Results: During the follow-up (9.1 4.9 years, range 0.4-20 years), 139 strokes and 120 coronary events occurred. In univariate analysis, patients with MetS had higher risk of the composite endpoint (hazard ratio 1.322, 95% confidence interval 1.035-1.688, P <0.05). Among the single components of MetS, only blood pressure level and impaired fasting glucose/diabetes were significantly associated with increased cardiovascular risk. After adjustment for age, previous events, estimated glomerular filtration rate, left ventricular hypertrophy and left atrial enlargement, the prognostic relevance of MetS was attenuated (hazard ratio 1.245, 95% confidence interval 0.974-1.591, P = 0.08). After further adjustment for the abovementioned variables and ambulatory blood pressure parameters and impaired fasting glucose/diabetes, Cox regression analysis showed that MetS was not independently associated with increased cardiovascular risk (hazard ratio 1.090, 95% confidence interval 0.805-1.475, P = 0.58).
Conclusions: In elderly treated hypertensive patients, MetS is associated with increased cardiovascular risk, but not independently of blood pressure and glucose levels and of organ damage
Morning Blood Pressure Surge, Dipping, and Risk of Coronary Events in Elderly Treated Hypertensive Patients
No full textAbstract
BACKGROUND:
The independent prognostic significance of morning surge (MS) of blood pressure (BP) is not yet clear. We investigated the association between MS of systolic BP and risk of coronary events in elderly treated hypertensive patients.
METHODS:
The occurrence of coronary events was evaluated in 1,191 elderly treated hypertensive patients (age range 60-90 years). Subjects were divided according to tertiles of MS of systolic BP of the population as a whole, by dipping status and by group-specific tertiles of MS of systolic BP in dippers and nondippers.
RESULTS:
During the follow-up (9.1±4.9 years, range 0.4-20 years), 120 coronary events occurred. In the population as a whole, coronary event risk was not significantly associated with tertiles of MS of systolic BP, whereas nondippers were at higher risk than dippers. When nondippers and dippers were analyzed separately, by group-specific tertiles of MS of systolic BP, coronary event risk was associated with MS of systolic BP in dippers but not in nondippers. After adjustment for various covariates, Cox regression analysis showed that dippers in the third tertile (>23mm Hg) of MS of systolic BP (hazard ratio 1.912, 95% confidence interval 1.048-3.488, P = 0.03) and nondippers (hazard ratio 1.739, 95% confidence interval 1.074-2.815, P = 0.02) were at higher coronary event risk than dippers with MS of systolic BP <23mm Hg .
CONCLUSIONS:
In elderly treated hypertensive patients, high MS of systolic BP predicts coronary events in dippers but not in nondippers. Nondippers, however, show higher risk of coronary events independently of MS in systolic BP
Prognostic Relevance of Metabolic Syndrome in Hypertensive Patients at Low-to-Medium Risk.
No full textBackground: The prognostic impact of metabolic syndrome
(MetS) in the hypertensive population at low-medium
risk is unknown. In this study, we evaluated the prognostic
relevance of MetS in hypertensive patients at low-medium
risk.
Methods: The occurrence of nonfatal and fatal cardiac
and cerebrovascular events was evaluated in 802 patients
with mild to moderate essential hypertension at low-medium
risk according to the 2003 World Health Organization/International
Society of Hypertension statement on the management
of hypertension. Among these patients, 218 (27.2%)
had MetS according to a modified National Cholesterol Education
Program Adult Treatment Panel III (NCEP ATP III)
definition (body mass index in place of waist circumference).
Results: During follow-up (6.9 +/- 3.1 years; range, 0.5
to 13.1 years, mean +/- SD), 58 first cardiovascular events
occurred. The event rates per 100 patient-years in patients
without and with MetS were 0.87 and 1.51, respectively.
Event-free survival was significantly different between
groups (P = .03). After adjustment for several covariates,
Cox regression analysis showed that cardiovascular risk
was significantly higher in patients with than in patients
without MetS (relative risk, 2.64; 95% confidence interval,
1.52 to 4.58; P = .001). Other independent predictors of
outcome were age, smoking habit, 24-h systolic BP, and
LDL cholesterol.
Conclusions: Hypertensive patients at low-medium
risk with MetS are at higher cardiovascular risk than those
without MetS. Metabolic syndrome may be a useful tool
for clinicians to identify subjects who are at increased risk
when traditional assessment may indicate low-medium
risk. Am J Hypertens 2007;20:1291–129
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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