1,721,056 research outputs found
Relationships between Hardiness and risk of Burn-out in a sample of 92 nurses working in Oncology and AIDS wards
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Capitale sociale: dalla teoria alla misurazione. L'uso dei questionari nell'analisi delle dimensioni
Il dibattito accademico sul capitale sociale non è giunto sinora a una definizione condivisa del termine, anche a causa delle difficoltà legate alla sua multi-dimensionalità (Bjørnskov e Mannermar Sønderskov, 2010; Sabatini, 2009). La definizione di riferimento è proposta dall’Organizzazione per la Cooperazione e lo Sviluppo Economico (OECD) di Parigi secondo cui il capitale sociale è costituito dai “network che assieme alle norme, ai valori e ai comuni intendimenti facilitano la cooperazione all’interno e tra i gruppi” (OECD, 2001). La ricerca ha utilizzato questa definizione di capitale sociale, analizzando nel dettaglio le sue due principali tipologie: il capitale sociale strutturale (reti di relazioni) e il capitale sociale cognitivo-normativo (norme e valori sociali) con specifico riguardo all’Approccio LEADER (AL). Le due tipologie di capitale sociale assieme alla governance sono state analizzate per mezzo di tre specifici questionari al direttore dei Gruppi di Azione Locale, ai soci e ai beneficiari di selezionati Misura del PSR
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
A tool for evaluating geothermal power exploitability: the case of Ischia volcanic island, Southern Italy
The paper proposes a method to evaluate the potential for electric power production at any site of possible
geothermal interest. Accounting for geological data of the reservoirs, the method allows the computation
of the available electrical power of the investigated site. Electrical energy production from geothermal
sources is realized through different techniques, such as single flash and double flash, dry steam, and binary
ORC plants. The technique chosen to be the most productive is determined by analyzing a specific
range of geofluid properties, mainly temperature and pressure. Moreover, each plant typology has a global
efficiency that may be correlated to geofluid enthalpy by empiric relations available in literature. The proposed
evaluation method brings together all these correlations, yielding the power availability from a geosource,
once its temperature and pressure are known. The method takes as input the geofluid available
flow rate, its pressure, temperature and non-condensable gas content. It defines the best plant option from
these parameters, calculates its global efficiency and finally returns the actual available power. For sites of
geothermic interest, the results of the application of
this new method clearly highlight the most suitable zones for power plants installations
T-cell malignancies following CAR T-Cell therapy: insights from the FDA Adverse Event Reporting System (FAERS)
Background: Concern about post-CAR T-cell lymphomas has recently emerged. Analysis of pharmacovigilance data contributes to continuous safety monitoring, especially for newly authorized medicines, like CAR-T therapies. Research design and methods: Individual case safety reports (ICSRs) reporting at least one CAR T-cell therapy as a suspect drug were extracted from the Food and Drug Administration Adverse Event Reporting System database up to 6 February 2024. Descriptive and disproportionality analysis were performed. Results: Seventeen ICSRs reported T-cell malignancies associated with CAR T-cell therapy. Gender distribution was similar between females and males, and adult patients accounted for 41.2% of ICSRs. All cases were serious, with 41.2% resulting in death. The most reported Preferred Terms (PTs) for T-cell malignancies was ‘T-cell lymphoma’ (70.6%). Over 70% of ICSRs reported at least one other adverse event, predominantly gastrointestinal disorders (14.3%). Axicabtagene ciloleucel and tisagenlecleucel were associated with a statistically higher reporting frequency of T-cell lymphoma compared to all other drugs (p-value <0.001, for both). Statistically higher reporting frequencies of ‘Haematological malignant tumors’ and ‘Malignant lymphomas’ SMQs emerged when tisagenlecleucel was compared with axicabtagene ciloleucel (p-value <0.001, for both). Conclusions: Axicabtagene ciloleucel and tisagenlecleucel may be associated with a higher reporting frequency of T-cell lymphoma than other drugs
Numerical modeling of gas-water-rock interaction in volcanic-hydrothermal environment: the Ischia Island (Southern Italy) case history
Quantitative models of hydrothermal fluid-mineral reaction: the Ischia case
The intricate pathways of fluid–mineral reactions occurring underneath active hydrothermal systems are explored in this
study by applying reaction path modelling to the Ischia case study. Ischia Island, in Southern Italy, hosts a well-developed and structurally complex hydrothermal system which, because of its heterogeneity in chemical and physical properties, is an ideal test sites for evaluating potentialities/limitations of quantitative geochemical models of hydrothermal reactions. We used the EQ3/6 software package, version 7.2b, to model reaction of infiltrating waters (mixtures of meteoric water and seawater in variable proportions) with Ischia’s reservoir rocks (the Mount Epomeo Green Tuff units; MEGT). The mineral assemblage and composition of such MEGT units were initially characterised by ad hoc designed optical microscopy and electron microprobe
analysis, showing that phenocrysts (dominantly alkali–feldspars and plagioclase) are set in a pervasively altered (with abundant clay minerals and zeolites) groundmass. Reaction of infiltrating waters with MEGT minerals was simulated over a range of realistic (for Ischia) temperatures (95–260 °C) and CO2 fugacities (10 exp-0.2 to 10 exp0.5) bar. During the model runs, a set of secondary minerals (selected based on independent information from alteration minerals’ studies) was allowed to precipitate from model solutions, when saturation was achieved. The compositional evolution of model solutions obtained in the 95–260 °C runs were finally compared with compositions of Ischia’s thermal groundwaters, demonstrating an overall agreement.
Our simulations, in particular, well reproduce the Mg-depleting maturation path of hydrothermal solutions, and have end-of-run model solutions whose Na–K–Mg compositions well reflect attainment of full-equilibrium conditions at run temperature.
High-temperature (180–260 °C) model runs are those best matching the Na–K–Mg compositions of Ischia’s most chemically mature water samples, supporting quenching of deep-reservoir conditions for these surface manifestations; whilst Fe, SiO2 and, to a lesser extent, SO4 contents of natural samples are better reproduced in low-temperature (95 °C) runs, suggesting that these species reflect conditions of water–rock interaction in the shallow hydrothermal environment. The ability of model runs to reproduce the compositional features of Ischia’s thermal manifestations, demonstrated here, adds supplementary confidence on reaction path modelling as a realistic and insightful representation of mineral–fluid hydrothermal reactions. Our
results, in particular, demonstrate the significant impact of host rock minerals’ assemblage in governing the paths and trends of hydrothermal fluids’ maturation
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