1,721,068 research outputs found

    Heredity and pituitary response to exercise-related stress in trained men

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    To evaluate the role of heredity in the pituitary responses to exercise-related stress, serum ACTH, β-endorphin, cortisol, GH, and PRL responses to a thirty-minute treadmill exercise at individual anaerobic threshold were evaluated in nine pairs of male monozygotic twin athletes. Hormone evaluations were performed before (-30, -15, 0 pre) and after exercise (0 post, +15, +30, +45, +60, and +90 min). The intraclass correlation coefficient (expression of within-pair resemblance) was computed for each hormone before and after exercise as area under curves (AUC), absolute values, and percentage of variation, respectively. The exercise-related stress condition induced a significant increase for all evaluated hormones before (anticipatory response) and/ or after exercise. As new data, we observed: 1) A significant within-pair resemblance for exercise-related GH and PRL increase (AUCs and/or absolute values), and for the percentage of variation of cortisol, and 2) the lack of significant resemblance for the observed increase of ACTH, cortisol and absolute β-endorphin serum concentration. This first co-twin control study supports the hypothesis that, in trained men, there are probably different relative roles for the influence of genetic factors on the pituitary hormones involved in physiological adaptation to exercise-related stress. Furthermore, our findings justify further investigations into this topic

    Vitamin D, sport and health: a still unresolved clinical issue

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    Vitamin D metabolites have a pleiotropic role in human physiology, both in static and dynamic conditions, and a lot of vitamin D-related biological effects could influence physical and sport performances in athletes. Probably due to different factors (e.g., drugs, doping, nutrition, ultraviolet B radiation exposure), in athletes a very high prevalence of vitamin D inadequacy (i.e., deficiency or insufficiency) has been observed. Vitamin D inadequacy in athletes could be associated with specific health risks and to alterations of functional capacities, potentially influencing the fine adjustment of physical performances during training and sport competitions. When risk factors for vitamin D inadequacy exist, a preventive vitamin D supplementation is indicated, and if a vitamin D inadequacy is diagnosed, its supplementation is recommended. Unfortunately, on these issues many concerns remain unresolved. Indeed, it is not clear if athletes should be classified as a special population at increased risk for vitamin D inadequacy; moreover, in comparison to the non-athletic population, it is still not clear if athletes should have different reference ranges and different optimal target levels for serum vitamin D, if they have additional health risks, and if they need different type of supplementations (doses) for prevention and/or replacement therapy. Moreover, in athletes also the abuse of vitamin D supplements for ergogenic purposes raise different ethical and safety concerns. In this review, the main physio-pathological, functional and clinical issues that relate vitamin D to the world of athletes are described

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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