382 research outputs found

    Can transit-time flow measurement improve graft patency and clinical outcome in patients undergoing coronary artery bypass grafting?

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    A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was if transit-time flow measurement (TTFM) can improve graft patency and clinical outcome in patients undergoing coronary surgery. Altogether 102 papers were found using the reported search, of which 10 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. The papers considered for the analysis focus attention on three major topics: intraoperative graft verification with the aim of improving immediate graft patency; predictive power of early-and mid-term graft patency and clinical outcome. Among TTFM parameters, according to different authors, mean graft flow is set at 10 or 15 ml/min; pulsatility index is set at three or five; insufficiency ratio is set by 3 or 4%. We conclude that TTFM is a reliable method to verify intraoperative graft patency. There is some evidence that checking graft patency intraoperatively may improve mid-term outcomes

    Predictive value of intraoperative transit-time flow measurement for short-term graft patency in coronary surgery.

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    Objective: The aim of this retrospective study was to evaluate the possibility to predict postoperative graft patency in coronary surgery by means of intraoperative transit-time flow measurement. Methods: Of 3567 patients submitted to isolated myocardial revascularization from June 1997 through June 2003, 157 (4.4%) underwent both intraoperative transittime flow measurement and angiography at follow-up. Thirty-six have been revascularized on a beating heart. Three hundred four grafts, 227 arterial conduits, and 77 saphenous vein grafts were checked. Results: No patients died, and none of them had an acute myocardial infarction within 12 months after the operation. After a mean of 6.7 4.8 months from the operation, 266 grafts (group A) were completely functioning, whereas 38 grafts (group B) had failed. The transit-time flow parameters recorded in the latter group had significantly lower mean flow and higher pulsatility index and percentage of backward flow values at both univariate and multivariate analysis. Moreover, mean flow values of 15 mL/min or less, pulsatility index values of 3.0 or greater, and percentage of backward flow values of 3.0% or greater were found to be independent variables for higher incidence of graft failure. Conclusions: Transit-time flow measurement represents a quick, easy, and reproducible method for intraoperative evaluation of graft function. The combination of the 3 major parameters (mean flow, pulsatility index, and percentage of backward flow) results in the chance to predic

    La tutela cautelare con effetti irreversibili

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    Nel contesto normativo attuale molti dei limiti tradizionali della tutela cautelare possono essere rivisti. L'apertura a misure cautelari atipiche e la possibilità ormai riconosciuta che il giudizio di merito determini una consumazione della discrezionalità amministrativa permettono di accedere a provvedimenti a contenuto anticipatorio, pur nei limiti consentiti dalla cognizione sommaria. In questo contesto, tuttavia, l'irreversibilità degli effetti della misura cautelare continua a costituire un insuperabile limite strutturale
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