1,356,149 research outputs found
A model for term selection in text categorization problems
No full textIn the last ten years, automatic Text Categorization (TC) has been gaining an increasing interest from the research community, due to the need to organize a massive number of digital documents. Following a machine learning paradigm, this paper presents a model which regards TC as a classification task supported by a wrapper approach and combines the utilization of a Genetic Algorithm (GA) with a filter. First, a filter is used to weigh the relevance of terms in documents. Then, the top-ranked terms are grouped in several nested sets of relatively small size. These sets are explored by a GA which extracts the subset of terms that best categorize documents. Experimental results on the Reuters-21578 dataset state the effectiveness of the proposed model and its competitiveness with the learning approaches proposed in the TC literature
CELL GROWTH AND CHOLESTEROL ESTERS
No full textIn recent years, understanding the molecular mechanisms involved in
intracellular cholesterol homeostasis has radically changed to include an
increasing number of structurally diverse receptors and carriers. The latest
additions have led to the implication of cholesterol in fundamental cell functions
such as cellular signaling and growth regulation. It appears that, at
least in some instances, adaptive regulation of cholesterol metabolism does
not protect cells indefinitely. Changes in this fine homeostatic regulation
may occur leading to pathologic consequences. The challenge of this book
has been to provide a useful point of reference on the mechanisms that
link cholesterol esters to cell growth and division. Particular attention has
been dedicated to the alterations in cholesterol esterification in two important
proliferative processes such as cancer and atherosclerosis.
The data presented in this book provide in vivo and in vitro evidence
of a strong relationship between cholesterol esterification and rate of cell
proliferation, and suggest that changes in the cholesterol esterification pathway
might represent fundamental events in developmental growth processes.
Although much progress has been made in tumor and atherosclerosis research,
and remarkable therapeutic successes have been achieved in both
these pathologies, several questions on the mechanisms underlying changes
in cholesterol metabolism and cell proliferation remain to be answered. Therefore,
the data acquire particular significance in view of the possibility that
the overall process of cholesterol esterification could play a key role in regulating
cell proliferation.
We hope that this book provides valuable information not only for
physicians, but also for teachers and students. As for the Editors, we would
like to look at this book as a milestone of a path started some seven years ago
when two friends, even though not so young any more, still deeply fascinated
by science and the potentiality of biology, put together their scientific
competence to face important matters such as the pharmacological control
of pathological proliferative processes from a novel perspective.
Alessandra Pani
Sandra Dessi
Brevi riflessioni in tema di quietanze a saldo miste a rinunzie ai diritti del lavoratore
No full textIl commento all’ordinanza in epigrafe si propone di esaminarne il testo, al fine di verificare la congruità della decisione della Corte di Cassazione rispetto ai principi generali del diritto del lavoro. Per centrare l’obiettivo l’autrice, dopo aver fatto un cenno alla controversia che ne costituisce l’oggetto, analizza in via generale la questione delle quietanze a saldo o liberatorie miste a rinunzie. Successivamente, si concentra sul provvedimento in commento e sulla posizione assunta dai giudici di legittimità in rapporto all’orientamento prevalente al riguardo.The note to the order in epigraph aims to examine the text, in order to verify the congruity of the decision of the Court of Cassation with the general principles of labor law. In order to achieve the objective, the author, after having reported the controversy that constitutes its object, analyzes in general the question of balance discharges or disclaimers mixed with renunciations. Subsequently, she focuses on the document in question and on the position taken by the judges of legitimacy in relation to the prevailing orientation in this regard
Low-Cost Geomatics Surveys for Emergency Interventions on Cultural Heritage. The Case of Historic Wall in Cagliari
No full textThe documentation and metric knowledge of cultural heritage is becoming an increasingly important need, especially concerning the state of degradation of some historical assets. In this context, the metric documentation of the investigated heritage becomes fundamental for a complete knowledge of the asset to support architects and engineers in the restoration process. Recently, methods and geomatics instrumentation have been developed for the survey of cultural heritage aiming at optimizing costs and time. For example, the Apple has integrated, into its devices, a LiDAR sensor capable of providing a 3D model of spaces and objects. The paper presents the studies of their potential about the study and metric documentation of cultural heritage, in particular in cases of extreme urgency and danger of the architectural asset where the speed of survey and non-contact with it becomes relevant. We focused on the case study of a perimeter wall of a historical building. The survey was performed with two fast and expeditious geomatics methods such as the Close Range Photogrammetry (CRP) and with the LiDAR Apple sensor of the iPad Pro. The wall was also surveyed with Terrestrial Laser Scanner methodology for the validation of the results
Experimental flutter testing of a low mass ratio NACA-16012 hydrofoil model
No full textThe steep increase in sailing speed experienced in the last decades, led yacht engineering to face fluid elastic instabilities issues resulting from the interaction of a light structure with the surrounding fluid flow at high speed. In this context, the authors of this paper decided to undertake an experimental campaign to test for flutter instability a low mass ratio hydrofoil model in CNR-INM water tank in Rome. The model is built as a segmented body to avoid structural participation of the components: this choice make the results prone to be employed for validation of reduced-order analytical or numerical models. The employed method, the final set-up and the testing procedure of the experimental campaign are detailed and the obtained measurements are presented and discussed. Beside the experimental campaign, the authors implemented an analytical reduce-order model to predict the flutter instability limit speed synthetizing the structure as a 2D spring-damper-mass system, and calculating the unsteadiness of the fluid loads generation by means of Theodorsen theory
Towards a New European Landscape: Countryside as Inhabited Ecosystem Model
Get PDFThe New European Bauhaus doesn't propose just a new way of interpreting health and welfare into a new sustainable productive paradigm but may well determine a deep re-establishment of our way of conceiving and inhabiting the European area. All along the Twentieth Century, cities have been the greatest human aspiration places but also consumption models of natural resources until the degree of "being human on earth" [1] reached a critical point. Meanwhile countryside has been "forgotten" although it is the place where human knowledge grows certainly more than in the cities [2]. The new Bauhaus deal, over the very pandemic period, has enabled to reflect on the manifold continental crises consequences but has also increased that human space re-establishing role of "design" starting from models radically different from the past. To this effect, the paper proposes two perspectives: Tracing into the multiple forms of historical European countryside-from the "inhabited" one [3] of the major continental plains to peripheral polyculture areas, from Mediterranean gardens and agricultural cities to multifunctional farmhouses-some paradigms which capture these new deep-changing energies. Interpreting European countryside as a "coevolution" field with cities and as a theatre of techno-ecological development enables to reformulate the human combination of producing/inhabiting into SDGs. Both perspectives will be illustrated through some modern and contemporary projects which were outstanding for their innovation with the aim of constructing a first state of art of countryside design into a new sustainable continental landscape vision
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