1,721,007 research outputs found
Expression of the survivin, inhibitor protein of apoptosis, in cutaneous malignant melanoma: immunohistochemical study
No full textGoing Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Survivin and p53 expression in patients with Crohn's disease: an immunohistochemical study
No full textCrohn’s disease (CD) is characterized by acute phases of
patchy transmural inflammation, involving any part of the
intestinal tract with intervening periods of remission. It has
been well established that patients with Crohn’s disease are at
increased risk of developing intestinal adenocarcinoma. The
regulation of apoptotic cell death may have an important
effect on the pathogenesis and progression of colon cancer.
Disturbance of apoptosis is known to be very crucial in neoplastic
progression and transformation. Mutations in the
proapoptotic and tumor suppressor gene p53 are associated
with neoplasia in ulcerative colitis, but little is understood of
their significance in Crohn’s disease. Members of the inhibitor
of the apoptosis protein (IAP) family including survivin are
expressed in many tumors. It is known that well differentiated
adenocarcinoma tend to express higher level of survivin than
normal mucosa. Expression of survivin was observed in the
cytoplasm of adenoma with dysplasia and colonrectal carcinoma
cells. In order to explore the role of p53 and survivin as
marker of neoplasia in CD patient, the aim of this study was to
evaluate, by immunohistochemical analysis, the expression and
distribution of p53 and survivin immunoreactive cells in a
series of Crohn’s disease bioptic tissues with apparently normal
adjacent tissues. The immunohistochemical study showed an
increase in p53 and survivin expression. Our results suggest
that p53 and survivin overexpression in CD patients may predispose
the intestinal mucosa to dysplasia that may progress to
a higher grade of neoplasia overtime
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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