1,720,965 research outputs found
Clonazione terapeutica e trasferimento genico in cellule staminali: applicazioni cliniche e aspetti etici
No full textConsiderazioni etiche e giuridiche sull'impiego delle biotecnologie
No full textParere del Comitato Nazionale per la Bioetica sull'impiego delle biotecnologie. Vengono discussi gli aspetti etici e giuridici della tematica
Cellule staminali e genetica di cellule somatiche
No full textIn questo volume un folto numero di ricercatori protagonisti della rivoluzione biotecnologica, compreso lo scienziato che ha clonato Dolly, cercano di spiegare i risultati e gli obiettivi della ricerca assieme alle future applicazioni dell'ingegneria genetica. Scopriremo che prevalgono le buone intenzioni, la volontà di alleviare le sofferenze del genere umano e anche degli animali, nostri compagni nel difficile cammino terreno. E per questo ci riferiamo al mondo come ad un Eldorado, un luogo dal quale tuttavia, per ora, dobbiamo ritornare per confrontarci con quello che non è ancora stato fatto. Per ragionare sulle motivazioni, sull'etica e trovare giustificazioni valide ad un viaggio stimolante ma apparentemente senza ritorno
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Isolation from the horse genome of a new DNA transposon belonging to the Tigger family.
No full textTigger elements are human DNA transposons homologous to the pogo element of Drosophila melanogaster. They contain an open reading frame for a transposase very similar to the major mammalian centromere protein CENP-B. We found in the horse genome a DNA element ( Ecatig3) sharing 88% homology with human Tigger3. The presence of Tigger elements in the horse genome confirms previous data that date these elements before the divergence between Perissodactyla and Primates (80-90 Myr ago). Copy number evaluation indicates that the horse element is much more abundant than its human counterpart. Southern blot analysis demonstrates that Ecatig3 elements are extremely homogeneous; this may indicate that the evolution of this DNA transposon has been driven by some kind of selection and has not been neutral
The Generation of a Human Minichromosome Vector Containing a loxP Site.
No full textA human chromosome vector has been constructed by inserting a homologous recombination site in an artificially modified minichromosome
Isolation and mapping of a polymorphic DNA sequence (Lambda-DMC.34) on the chromosome 2 (D2S63)
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