1,721,119 research outputs found
Organization and regulation of the electricty Supply Industry in Italy
The book describes the process of liberalization of the electricity Supply Industry in EU countries. The chapter written is focused on the Italian case
Economia e politica delle fonti rinnovabili e della cogenerazione
collana Economia e politica dell'energia e dell'ambient
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Predictive markers and driving factors behind Richter syndrome development
Transformation of chronic lymphocytic leukemia (CLL) to diffuse large B-cell lymphoma (DLBCL) is known as Richter syndrome (RS). In the entire CLL population, the cumulative prevalence of RS development steadily increases at a rate of 1% per year. Considering conventional predictors of CLL, patient subgroups at high risk of developing RS are characterized by the expression of CD38, absence of del13q14, and a lymph node size >3 cm. Novel risk factors for predicting RS development at CLL diagnosis have been recently identified and include: the host genotype of the CD38 locus and of other genes; telomere length of CLL cells; stereotyped B-cell receptor; and usage of specific immunoglobulin variable genes (IGHV4-39). Importantly, although some risk factors predict both CLL progression and transformation to RS, others (CD38 genotype, absence of del13q14, IGHV4-39 usage, stereotyped B-cell receptor) appear to specifically predict RS. The definition of RS encompasses at least two different conditions: DLBCLs that are clonally related to the pre-existing CLL (accounting for most cases), or DLBCL unrelated to the CLL clone. The transition from CLL to clonally related RS is accompanied by the acquisition of novel genetic alterations that may account for the chemorefractoriness of RS. Genome-wide studies that are currently ongoing are important for identifying novel molecular lesions implicated in RS that might represent a suitable target for future therapeutic strategies
Loco-regional and diffuse abdominal complications of hepatocellular carcinoma: imaging findings on contrast-enhanced CT and MR imaging.
Multidetector CT mutphasic investigation in the treatment planning of hepatocarcinoma nodules in cirrhotic liver: clinical results and assessment of therapeutic efficacy.
One size does not fit all: alcune riflessioni sulla proposta di riforma dei servizi pubblici locali in Italia
L'articolo analizza l'evoluzione dei modelli organizzativi per i servizi pubblici locali in Europa e discute alcune implicazioni delle proposte di riforma all'esame del Parlament
Differenziazione con RM delle strie perirettali fibrotiche dall’infiltrazione tumorale dopo radiochemioterapia neoadiuvante in pazienti con carcinoma rettale mediante sequenza SPIR con gadolinio
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