1,721,005 research outputs found
ONCOGENES AND GROWTH FACTORS IN OVARIAN EPITHELIAL TUMORS.
No full textThe present data underline the existence of over-expression of several oncogenes in common epithelial tumours. The detection of oncogene expression in ovarian tumours may be useful in predicting tumor prognosis, and in determining genetic relationships between histologically similar but clinically dissimilar tumor types
Joint analysis of cost and energy savings for preliminary design alternative assessment
Full text linkThe building sector plays a central role in addressing the problem of global energy consumption. Therefore, effective design measures need to be taken to ensure efficient usage and management of new structures. The challenging task for designers is to reduce energy demands while maintaining a high-quality indoor environment and low costs of construction and operations. This study proposes a methodological framework that enables decision-makers to resolve conflicts between energy demand and life cycle costs. A case study is analyzed to validate the proposed method, adopting different solutions for walls, roofs, floors, windows, window-to-wall ratios and geographical locations. Models are created on the basis of all the possible combinations between these elements, enriched by their thermal properties and construction/management costs. After the alternative models are defined, energy analyses are carried out for an estimation of consumption. By calculating the total cost of each model as the sum of construction, energy and maintenance costs, a joint analysis is carried out for variable life cycles. The obtained results from the proposed method confirm the importance of a preliminary assessment from both energy and cost points of view, and demonstrate the impact of considering different building life cycles on the choice of design alternatives
The worldwide physical height datum project
Full text linkThe definition of a common global vertical coordinate system is nowadays one of the key points in Geodesy. With the advent of GNSS, a coherent global height has been made available to users. The ellipsoidal height can be obtained with respect to a given geocentric ellipsoid in a fast and precise way using GNSS techniques. On the other hand, the traditional orthometric height is not coherent at global scale. Spirit levelling allows the estimation of height increments so that orthometric heights of surveyed points can be obtained starting from a benchmark of known orthometric heights. As it is well known, this vertical coordinate refers to the geoid, which is assumed to be coincident to the mean sea level. By means of a tide gauge, the mean sea level is estimated and thus a point of known orthometric height is defined. This assumption, which was acceptable in the past, became obsolete given the level of precision which is now required. Based on the altimetry observation, one can precisely quantify the existing discrepancy between geoid and mean sea level that can amount to 1 ÷ 2 m at global scale. Therefore, different tide gauges provide biased estimates of the geoid, given the discrepancy between this equipotential surface and the mean sea level. Also, in the last years, another vertical coordinate was used, the normal height that was introduced in the context of the Molodensky theory. In this paper, a review of the existing different height systems is given and the relationships among them are revised. Furthermore, an approach for unifying normal height referring to different tide gauges is presented and applied to the Italian test case. Finally, a method for defining a physical height system that is globally coherent is discussed in the context of the definition of the International Height Reference System/Frame, a project supported by the Global Geodetic Observing System of the International Association of Geodesy (IAG). This project was established in 2015 during the XXVI IAG General Assembly in Prague as described in IAG Resolution no. 1 that was presented and adopted there
A procedure for automating energy analyses in the bim context exploiting artificial neural networks and transfer learning technique
Full text linkOne of the main benefits of Building Information Modelling is the capability of improving the decision-making process thanks performing what-if tests on digital twins of the building to be realized. Pairing BIM models to Building Energy Models allows designers to determine in advance the energy consumption of the building, improving sustainability of the construction. The challenge is to consider as many elements involved in the energy balance as possible and shuffling their parameters within a certain range. In this work, the automatic creation of a relevant set of design options to be analyzed for searching the optimum has been carried out. Firstly, the usual workflow that would be applied manually has been automatically followed by running scripts and codes, depending just on the initial setup given by the user. Although the procedure is very resource consuming, the main advancement relies in the reduction of the manual intervention and the possibility of creating large datasets of design options, avoiding gross errors. Secondly, Artificial Neural Networks and Transfer Learning techniques are applied to speed up the process of dataset creation. With such approach, the same dataset has been created, with about 30% of initial data and without significant loss of accuracy
A web-based BIM-AR quality management system for structural elements
Full text linkThis paper investigates quality management (QM) during the execution phase of structural elements by proposing, developing, and testing a complete framework by integrating building information modeling (BIM) and augmented reality (AR) technology. QMduring execution is boosted by BIM-AR integration through a dedicated web-based system aimed at reducing the occurrence of omissions and negligence. With such a system, efficiency is improved by allowing the entering of inspection data directly in a shared digital environment, where people involved in QM have permanent access to updated information and inspection results, clearly organized, and entered in real time. The system has been developed in the asp.net framework using C# language where, by generating a web-based checklist and establishing its link to AR, it can enhance the process of information extraction from industry foundation class (IFC) 4D BIM models and the recording of inspection data. A test has been performed on a real case study in Budapest, to assess the effectiveness of the system in the field. Results demonstrate the following benefits brought by such a type of QM system: improved understanding of the design, access to information, and overview of the quality status of the project, leading to reductions in defects and reworking, as well as improved and quicker response and decision-making
Interoperability analyses of BIM platforms for construction management
Full text linkIt is incontrovertible that an exchange of files is essentially required at several stages of the workflow in the architecture, engineering, and construction (AEC) industry. Therefore, investigating and detecting the capabilities/inabilities of building information modeling (BIM) software packages with respect to interoperability can be informative to stakeholders who exchange data between various BIM packages. The work presented in this paper includes a discussion on the interoperability of different software platforms commonly used in the AEC industry. Although, in theory, flawless interoperability of some types of files between different BIM platforms is ensured, in practical applications, this is not always the case. Hence, this research aims to identify faults in data exchange by assessing different possible scenarios where a sample Industry Foundation Classes (IFC) four-dimensions (4D) BIM model and related Gantt charts are exchanged. Throughout the interoperability analysis of both IFC file and Gantt charts, the following checks were carried out: geometrical and nongeometrical information exchange through IFC files, 4D information correct readability, and presence of missing schedule information in Gantt charts after their import/export procedure. The results show that interoperability between the analyzed platforms is not always ensured, providing useful insight into realistic scenarios
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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