1,721,076 research outputs found
Comment on Two Time Scales and Violation of the Fluctuation-Dissipation Theorem in a Finite Dimensional Model for Structural Glasses
No full textAggregation of fibrils and plaques in amyloid molecular systems
No full textAmyloidlike proteins form highly organized aggregates, such as fibrils and plaques, preceded by the assembly of a wide range of unstructured oligomers and protofibrils. Despite their importance in a number of human neurodegenerative diseases, a comprehensive understanding of their kinetics and thermodynamics is still missing. We investigate, by computer simulations, a realistic model of amyloid molecules interacting via the experimentally determined Derjaguin-Landau-Verwey-Overbeek potential and derive its phase diagram. We show that fibrils and plaques, along with their precursors, correspond to different equilibrium and metastable thermodynamics phases and discuss the dynamical mechanisms leading to the nucleation and self-assembly of large scale structures
Cluster formulation of spin glasses and the frustrated percolation model: statics and dynamics
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Nonexponential relaxation in fully frustrated models
No full textWe study the dynamical properties of the fully frustrated Ising model. Due to the absence of disorder the model, contrary to spin glass, does not exhibit any Griffiths phase, which has been associated to nonexponential relaxation dynamics. Nevertheless, we find numerically that the model exhibits; a stretched exponential behavior below a temperature T-p corresponding to the percolation transition of the Kasteleyn-Fortuin clusters. We have also found that the critical behavior of these clusters for a fully frustrated q-state spin model at the percolation threshold is strongly affected by frustration. In fact while in the absence of frustration the q=1 limit gives random percolation. in the presence of frustration the critical behavior is in the same universality class of the ferromagnetic q=1/2-state Potts model
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